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Träfflista för sökning "WFRF:(Lee MJ) srt2:(2020-2024)"

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1.	Jakobsson, J., et al. (author) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 2021 In: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 17:1, s. 1-382 Journal article (peer-reviewed)
2.	2021 swepub:Mat__t
3.	Brauer, M, et al. (author) Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021 2024 In: Lancet (London, England). - : Elsevier B.V.. - 1474-547X .- 0140-6736. ; 403:10440, s. 2162-2203 Journal article (peer-reviewed)
4.	Niemi, MEK, et al. (author) 2021 swepub:Mat__t
5.	Kanai, M, et al. (author) 2023 swepub:Mat__t
6.	Naghavi, M, et al. (author) Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021 2024 In: Lancet (London, England). - 1474-547X .- 0140-6736. ; 403:10440, s. 2100-2132 Journal article (peer-reviewed)
7.	Bhattacharjee, NV, et al. (author) Global fertility in 204 countries and territories, 1950-2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 2024 In: Lancet (London, England). - 1474-547X .- 0140-6736. ; 403:10440, s. 2057-2099 Journal article (peer-reviewed)
8.	2021 swepub:Mat__t
9.	Tabiri, S, et al. (author) 2021 swepub:Mat__t
10.	Campbell, PJ, et al. (author) Pan-cancer analysis of whole genomes 2020 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 578:7793, s. 82- Journal article (peer-reviewed)abstract Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale1–3. Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4–5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter4; identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation5,6; analyses timings and patterns of tumour evolution7; describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity8,9; and evaluates a range of more-specialized features of cancer genomes8,10–18.

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Result 1-10 of 140

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Type of publication: journal article (132); conference paper (1)

Type of content: peer-reviewed (117); other academic/artistic (16)

Author/Editor: Negoi, I (39); Fischer, F (37); Jonas, JB (37); Postma, MJ (35); Kim, YJ (34); Kisa, A (34); show more...; Mohammed, S (34); Arabloo, J (33); Mokdad, AH (33); Rawaf, S (33); Shaikh, MA (33); Hosseinzadeh, M (32); Mestrovic, T (32); Waheed, Y (32); Olagunju, AT (31); Samy, AM (31); Andrei, CL (30); Banach, M (30); Chattu, VK (30); Hay, SI (30); Jozwiak, JJ (30); Lee, PH (30); Singh, JA (30); Tovani-Palone, MR (30); Gupta, R. (29); Butt, ZA (29); Chu, DT (29); Diaz, D (29); Kisa, S (29); Sathian, B (29); Ibitoye, SE (28); Koyanagi, A (28); Krishan, K (28); Menezes, RG (28); Monasta, L (28); Rawaf, DL (28); Rezaei, N (27); Aljunid, SM (27); Ilesanmi, OS (27); Ilic, MD (27); Lasrado, S (27); Naghavi, M (27); Padubidri, JR (27); Alvis-Guzman, N (26); Basu, S (26); Islam, SMS (26); Mansournia, MA (26); Mirrakhimov, EM (26); Sahebkar, A (26); Shiri, R (26); show less...

University: Karolinska Institutet (138); Uppsala University (29); Lund University (24); University of Gothenburg (17); Umeå University (10); Högskolan Dalarna (10); show more...; Stockholm University (5); Örebro University (4); University of Skövde (4); Jönköping University (3); Kristianstad University College (1); Luleå University of Technology (1); Linköping University (1); Swedish University of Agricultural Sciences (1); show less...

Language: English (140)

Research subject (UKÄ/SCB): Medical and Health Sciences (59); Social Sciences (4); Natural sciences (3)

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