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1.	Jakobsson, P-J, et al. (author) Characterization of extracellular histidyl-tRNA synthetase in myositis 2016 In: Scandinavian Journal of Rheumatology. - : BMJ PUBLISHING GROUP. - 0300-9742 .- 1502-7732. ; 75, s. 736-737 Journal article (other academic/artistic)
2.	Ålander, J., et al. (author) Microsomal glutathione transferase 1 exhibits one-third-of-the-sites-reactivity towards glutathione 2009 In: Archives of Biochemistry and Biophysics. - : Elsevier BV. - 0003-9861 .- 1096-0384. ; 487:1, s. 42-48 Journal article (peer-reviewed)abstract The trimeric membrane protein microsomal glutathione transferase 1 (MGST1) possesses glutathione transferase and peroxidase activity. Previous data indicated one active site/trimer whereas structural data suggests three GSH-binding sites. Here we have determined ligand interactions of MGST1 by several techniques. Nanoelectrospray mass spectrometry of native MGST1 revealed binding of three GSH molecules/trimer and equilibrium dialysis showed three product molecules/trimer (K(d) = 320 +/- 50 mu M). All three product molecules Could be competed out with GSH. Reinvestigation of GSH-binding showed one high affinity site per trimer, consistent with earlier data. Using single turnover stopped flow kinetic measurements, Kd could be determined for a low affinity GSH-binding site (2.5 +/- 0.5 mu M). Thus we can reconcile previous observations and show here that MGST1 contains three active sites with different affinities for GSH and that only the high affinity site is catalytically competent.
3.	Estelius, J, et al. (author) Mass spectrometry-based analysis of cerebrospinal fluid from arthritis patients-immune-related candidate proteins affected by TNF blocking treatment 2019 In: Arthritis research & therapy. - : Springer Science and Business Media LLC. - 1478-6362. ; 21:1, s. 60- Journal article (peer-reviewed)
4.	Fernandes-Cerqueira, C, et al. (author) Extracellular Histidyl-tRNA Synthetase in Myositis 2016 In: ARTHRITIS & RHEUMATOLOGY. - 2326-5191. ; 68 Conference paper (other academic/artistic)
5.	Lengqvist, J, et al. (author) Robustness and accuracy of high speed LC-MS separations for global peptide quantitation and biomarker discovery 2009 In: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. - : Elsevier BV. - 1873-376X. ; 877:13, s. 1306-1316 Journal article (peer-reviewed)
6.	Ossipova, E., et al. (author) Exploring cerebrospinal fluid proteome in fibromyalgia 2018 In: Annals of the Rheumatic Diseases. - : BMJ Publishing Group Ltd. - 0003-4967 .- 1468-2060. ; 77, s. 1643-1644 Journal article (other academic/artistic)
7.	Berg, L., et al. (author) Characterizing the effects of epigenetic regulation in assays using peripheral blood mononuclear cells from patients with inflammatory diseases 2016 In: Scandinavian Journal of Rheumatology. - 0300-9742 .- 1502-7732. ; 45, s. 44-45 Journal article (other academic/artistic)
8.	Eriksson, H, et al. (author) Assessment of two quantitative methods for analyzing the membrane proteome of human adrenal tumor tissue 2006 In: MOLECULAR & CELLULAR PROTEOMICS. - 1535-9476. ; 5:10, s. S190-S190 Conference paper (other academic/artistic)
9.	Lengqvist, J, et al. (author) Detection of a receptor-ligand non-covalent complex using a triple quadrupole mass spectrometer 2002 In: Rapid communications in mass spectrometry : RCM. - : Wiley. - 0951-4198. ; 16:20, s. 2003-2006 Journal article (other academic/artistic)
10.	Lengqvist, J, et al. (author) Electrospray mass spectrometry for the direct accurate mass measurement of ligands in complex with the retinoid X receptor alpha ligand binding domain 2005 In: Journal of the American Society for Mass Spectrometry. - : American Chemical Society (ACS). - 1044-0305. ; 16:10, s. 1631-1640 Journal article (peer-reviewed)

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Type of publication: journal article (19); conference paper (8)

Type of content: peer-reviewed (16); other academic/artistic (11)

Author/Editor: Griffiths, WJ (6); Perlmann, T (5); Jakobsson, PJ (5); Lewensohn, R. (3); Morgenstern, R (3); Nordlund, P (3); show more...; Berg, L (2); Gudmundsson, GH (2); Grunewald, J (2); Agerberth, B (2); Eriksson, H (2); Kultima, Kim (2); Fernandes-Cerqueira, ... (2); Notarnicola, A (2); Lampa, J (2); Jornvall, H (2); Larsson, A (2); Albrecht, I (2); Fathi, M (2); Yang, Y. (1); Chen, T. (1); Bergh, J (1); Adams, C. (1); Larsson, Rolf (1); Gustafsson, Mats (1); Ramos, A. (1); Khademi, M. (1); Wagner, J. (1); Skuladottir, GV (1); Emami Khoonsari, Pay ... (1); Chen, D (1); Willson, TM (1); Sundstrom, M (1); Lundberg, IE (1); Viktorsson, K. (1); Kosek, Eva (1); Lundberg, I (1); Rönnelid, Johan (1); Jansson, A (1); Gunnarsson, I (1); Ronnelid, J (1); Wigren, E (1); Zubarev, R (1); Chen, LY (1); Eriksson, S. (1); Arenas, E (1); Surova, O (1); Rodriguez, FJ (1); Alander, J (1); Svenungsson, E (1); show less...

University: Karolinska Institutet (27); Royal Institute of Technology (3); Uppsala University (3); Swedish University of Agricultural Sciences (1)

Language: English (27)

Research subject (UKÄ/SCB): Medical and Health Sciences (6); Natural sciences (1)

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