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Träfflista för sökning "WFRF:(Li XZ) srt2:(1999)"

Search: WFRF:(Li XZ) > (1999)

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1.
  • Li, XZ, et al. (author)
  • HREM study and structure modeling of the η′ phase, the hardening precipitates in commercial Al-Zn-Mg alloys
  • 1999
  • In: Acta Materialia. - 1359-6454. ; 47:9, s. 2651-2659
  • Journal article (peer-reviewed)abstract
    • The structure of the η′ phase, one of the most important age-hardening precipitates in commercial Al-Zn-Mg alloys, has been studied at the atomic level by means of high-resolution electron microscopy (HREM). A structural model of the η′ phase has been constructed on the basis of the structural characteristics in the observed images and the structure of the η-MgZn2 phase. Image simulation of this model shows a good agreement between calculated and experimental images. Comparison of this model with the early existing model on the basis of the X-ray diffraction is also given.
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2.
  • Zhang, B, et al. (author)
  • Discovery of a small molecule insulin mimetic with antidiabetic activity in mice
  • 1999
  • In: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 284:5416, s. 974-977
  • Journal article (peer-reviewed)abstract
    • Insulin elicits a spectrum of biological responses by binding to its cell surface receptor. In a screen for small molecules that activate the human insulin receptor tyrosine kinase, a nonpeptidyl fungal metabolite (L-783,281) was identified that acted as an insulin mimetic in several biochemical and cellular assays. The compound was selective for insulin receptor versus insulin-like growth factor I (IGFI) receptor and other receptor tyrosine kinases. Oral administration of L-783,281 to two mouse models of diabetes resulted in significant lowering in blood glucose levels. These results demonstrate the feasibility of discovering novel insulin receptor activators that may lead to new therapies for diabetes.
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  • Result 1-2 of 2
Type of publication
journal article (2)
Type of content
peer-reviewed (2)
Author/Editor
Zhang, Y. (1)
Zhang, B. (1)
Zierath, JR (1)
Wallenberg, LR (1)
Hansen, V (1)
Li, XZ (1)
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Mao, XZ (1)
Li, ZH (1)
Moller, DE (1)
Gjønnes, J (1)
Salituro, G (1)
Smith, RG (1)
Griffin, P (1)
Szalkowski, D (1)
Royo, I (1)
Vilella, D (1)
Diez, MT (1)
Pelaez, F (1)
Ruby, C (1)
Kendall, RL (1)
Calaycay, J (1)
Heck, JV (1)
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University
Lund University (1)
Karolinska Institutet (1)
Language
English (2)
Research subject (UKÄ/SCB)
Natural sciences (1)
Year
1999 (2)Undo refine

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