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- Abdelaziz, Ahmed, et al.
(author)
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Survey on network virtualization using openflow : Taxonomy, opportunities, and open issues
- 2016
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In: KSII Transactions on Internet and Information Systems. - : Korean Society for Internet Information (KSII). - 1976-7277. ; 10:10, s. 4902-4932
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Journal article (peer-reviewed)abstract
- The popularity of network virtualization has recently regained considerable momentum because of the emergence of OpenFlow technology. It is essentially decouples a data plane from a control plane and promotes hardware programmability. Subsequently, OpenFlow facilitates the implementation of network virtualization. This study aims to provide an overview of different approaches to create a virtual network using OpenFlow technology. The paper also presents the OpenFlow components to compare conventional network architecture with OpenFlow network architecture, particularly in terms of the virtualization. A thematic OpenFlow network virtualization taxonomy is devised to categorize network virtualization approaches. Several testbeds that support OpenFlow network virtualization are discussed with case studies to show the capabilities of OpenFlow virtualization. Moreover, the advantages of popular OpenFlow controllers that are designed to enhance network virtualization is compared and analyzed. Finally, we present key research challenges that mainly focus on security, scalability, reliability, isolation, and monitoring in the OpenFlow virtual environment. Numerous potential directions to tackle the problems related to OpenFlow network virtualization are likewise discussed
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- Ademuyiwa, Adesoji O., et al.
(author)
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Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries
- 2016
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In: BMJ Global Health. - : BMJ Publishing Group Ltd. - 2059-7908. ; 1:4
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Journal article (peer-reviewed)abstract
- Background: Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries globally.Methods: Multicentre, international, prospective, cohort study. Self-selected surgical units performing emergency abdominal surgery submitted prespecified data for consecutive children aged <16 years during a 2-week period between July and December 2014. The United Nation's Human Development Index (HDI) was used to stratify countries. The main outcome measure was 30-day postoperative mortality, analysed by multilevel logistic regression.Results: This study included 1409 patients from 253 centres in 43 countries; 282 children were under 2 years of age. Among them, 265 (18.8%) were from low-HDI, 450 (31.9%) from middle-HDI and 694 (49.3%) from high-HDI countries. The most common operations performed were appendectomy, small bowel resection, pyloromyotomy and correction of intussusception. After adjustment for patient and hospital risk factors, child mortality at 30 days was significantly higher in low-HDI (adjusted OR 7.14 (95% CI 2.52 to 20.23), p<0.001) and middle-HDI (4.42 (1.44 to 13.56), p=0.009) countries compared with high-HDI countries, translating to 40 excess deaths per 1000 procedures performed.Conclusions: Adjusted mortality in children following emergency abdominal surgery may be as high as 7 times greater in low-HDI and middle-HDI countries compared with high-HDI countries. Effective provision of emergency essential surgery should be a key priority for global child health agendas.
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- Banerjee, R., et al.
(author)
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Realization of Hofstadter's butterfly and a one-way edge mode in a polaritonic system
- 2018
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In: Physical Review B. - : AMER PHYSICAL SOC. - 2469-9950 .- 2469-9969. ; 98:7
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Journal article (peer-reviewed)abstract
- We present a scheme to generate an artificial gauge field for the system of neutral bosons, represented by polaritons in micropillars arranged into a square lattice. The splitting between the two polarizations of the micropillars breaks the time-reversal symmetry (TRS) and results in the effective phase-dependent hopping between cavities. This can allow for engineering a nonzero flux on the plaquette, corresponding to an artificial magnetic field. Changing the phase, we observe a characteristic Hofstadter's butterfly pattern and the appearance of chiral edge states for a finite-size structure. For long-lived polaritons, we show that the propagation of wave packets at the edge is robust against disorder. Moreover, given the inherent driven-dissipative nature of polariton lattices, we find that the system can exhibit topological lasing, recently discovered for active ring cavity arrays. The results point to a static way to realize artificial magnetic field in neutral spinful systems, avoiding the periodic modulation of the parameters or strong spin-orbit interaction. Ultimately, the described system can allow for high-power topological single-mode lasing which is robust to imperfections.
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- Chin, K. L., et al.
(author)
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Impact of eplerenone on major cardiovascular outcomes in patients with systolic heart failure according to baseline heart rate
- 2019
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In: Clinical Research in Cardiology. - : Springer Science and Business Media LLC. - 1861-0684 .- 1861-0692. ; 108:7, s. 806-814
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Journal article (peer-reviewed)abstract
- BackgroundIncreased resting heart rate is a risk factor for cardiovascular mortality and morbidity. Mineralocorticoid receptor antagonists (MRAs) have been shown to improve cardiac sympathetic nerve activity, reduce heart rate and attenuate left ventricular remodelling. Whether or not the beneficial effects of MRA are affected by heart rate in heart failure patients with reduced ejection fraction (HFREF) is unclear.MethodsWe undertook a secondary analysis of data from the Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure study to assess if clinical outcomes, as well as the efficacy of eplerenone, varied according to heart rate at baseline.ResultsHigh resting heart rate of 80bpm and above predisposed patients to greater risk of all outcomes in the trial, regardless of treatment allocation. The beneficial effects of eplerenone were observed across all categories of heart rate. Eplerenone reduced the risk of primary endpoint, the composite of cardiovascular death and hospitalisation for heart failure, by 30% (aHR 0.70; 95% CI 0.54-0.91) in subjects with heart rate80bpm, and by 48% (aHR 0.52; 95% CI 0.33-0.81) in subjects with heart rate60bpm. Eplerenone also reduced the risks of hospitalisation for heart failure, cardiovascular deaths and all-cause deaths independently of baseline heart rate.ConclusionsBaseline heart rate appears to be an important predictor of major clinical outcome events in patients with HFREF, as has been previously reported. The benefits of eplerenone were preserved across all categories of baseline heart rate, without observed heterogeneity in the responses.
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