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Träfflista för sökning "WFRF:(Lindman H.) srt2:(1996-1999)"

Search: WFRF:(Lindman H.) > (1996-1999)

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  • Billsten, P, et al. (author)
  • Adsorption of human carbonic anhydrase II onto silicon oxides surfaces : The effects of truncation in the N-terminal region
  • 1998
  • In: The Colloid Science of Lipids New Paradigms for Self-Assembly in Science and Technology. - 1435-1536 .- 0340-255X. - 9783798511125 - 9783798516557 ; 108, s. 161-165
  • Conference paper (peer-reviewed)abstract
    • The adsorption of human carbonic anhydrase II pseudo-wild type (HCAIIpwt) and an N-terminally truncated version thereof onto silica surfaces were studied. The amount adsorbed and the adsorption kinetics were measured using in situ ellipsometry. A substantial difference was seen between the two proteins. The adsorbed amount of the truncated version (2.53 mg/m2) indicates an end-on orientation, while the HCAIIpwt seems to adsorb side-on (1.84 mg/m2). It is suggested that the orientation effects arise from the truncation. The truncation is known to unfold the two most N-terminal helical segments, which could inhibit adsorption with the N-terminal region facing the surface, due to steric repulsion.
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  • Result 1-6 of 6

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