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| 2. |
- Cardell, L O, et al.
(author)
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Genes regulating molecular and cellular functions in noninfectious nonallergic rhinitis.
- 2009
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In: Allergy. - : Wiley. - 1398-9995 .- 0105-4538. ; 64:9, s. 1301-8
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Journal article (peer-reviewed)abstract
- Chronic noninfectious, nonallergic rhinitis (NINAR) is a complex syndrome with a principally unknown pathophysiology. New technology has made it possible to examine differentially expressed genes and according to network theory, genes connected by their function that might have key roles in the disease.
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| 3. |
- Lagergren, Fredrik, et al.
(author)
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Net primary production and light use efficiency in a mixed coniferous forest in Sweden
- 2005
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In: Plant, Cell and Environment. - : Wiley. - 0140-7791 .- 1365-3040. ; 28:3, s. 412-423
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Journal article (peer-reviewed)abstract
- Simple light use efficiency (epsilon) models of net primary production (NPP) have recently been given great attention (NPP = epsilon x absorbed photosynthetically active radiation). The underlying relationships have, however, not been much studied on a time step less than a month. In this study daily NPP was estimated as the sum of net ecosystem exchange (NEE) and heterotrophic respiration (R-h) of a mixed pine and spruce forest in Sweden. NEE was measured by eddy correlation technique and R-h was estimated from measurements of forest floor respiration (R-f) and the root share of R-f. The total yearly NPP was on average 810 g C m(-2) year(-1) for 3 years and yearly epsilon was between 0.58 and 0.71 g C MJ(-1), which is high in comparison with other studies. There was a seasonal trend in epsilon with a relatively constant level of approximately 0.90 g C MJ(-1) from April to September Daily NPP did not increase for daily intercepted radiation above 6 MJ m(-2) d(-1), indicating that between-years variation in NPP is not directly dependent on total Q(i). The light was most efficiently used at an average daytime temperature of around 15 degreesC. At daytime vapour pressure deficit above 1400 Pa epsilon was reduced by approximately 50%.
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| 6. |
- Lundblad, Martin, et al.
(author)
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Chronic intermittent L-DOPA treatment induces changes in dopamine release
- 2009
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In: Journal of Neurochemistry. - : Wiley. - 0022-3042 .- 1471-4159. ; 108:4, s. 998-1008
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Journal article (peer-reviewed)abstract
- 3,4-Dihydroxyphenyl-l-alanine (l-DOPA)-induced dyskinesia often develops as a side effect of chronic l-DOPA therapy. This study was undertaken to investigate dopamine (DA) release upon l-DOPA treatment. Chronoamperometric measurements were performed in unilaterally DA-depleted rats, chronically treated with l-DOPA, resulting in dyskinetic and non-dyskinetic animals. Normal and lesioned l-DOPA naïve animals were used as controls. Potassium-evoked DA releases were significantly reduced in intact sides of animals undertaken chronic l-DOPA treatment, independent on dyskinetic behavior. Acute l-DOPA further attenuated the amplitude of the DA release in the control sides. In DA-depleted striata, no difference was found in potassium-evoked DA releases, and acute l-DOPA did not affect the amplitude. While immunoreactivity to serotonin uptake transporter was higher in lesioned striata of animals displaying dyskinetic behavior, no correlation could be documented between serotonin transporter-positive nerve fiber density and the amplitude of released DA. In conclusions, the amplitude of potassium-evoked DA release is attenuated in intact striatum after chronic intermittent l-DOPA treatment. No change in amplitude was found in DA-denervated sides of either dyskinetic or non-dyskinetic animals, while release kinetics were changed. This indicates the importance of studying DA release dynamics for the understanding of both beneficial and adverse effects of l-DOPA replacement therapy.
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