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Träfflista för sökning "WFRF:(Magi M) srt2:(2015-2019)"

Search: WFRF:(Magi M) > (2015-2019)

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Enumeration	Reference	Cover	Find
1.	2017 swepub:Mat__t
2.	Bonaca, MP, et al. (author) Long-term use of ticagrelor in patients with prior myocardial infarction 2015 In: The New England journal of medicine. - 1533-4406. ; 372:19, s. 1791-1800 Journal article (peer-reviewed)
3.	Clark, DW, et al. (author) Associations of autozygosity with a broad range of human phenotypes 2019 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 4957- Journal article (peer-reviewed)abstract In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction between close relatives is both rare and frequently associated with confounding social factors. Here, using genomic inbreeding coefficients (FROH) for >1.4 million individuals, we show that FROH is significantly associated (p < 0.0005) with apparently deleterious changes in 32 out of 100 traits analysed. These changes are associated with runs of homozygosity (ROH), but not with common variant homozygosity, suggesting that genetic variants associated with inbreeding depression are predominantly rare. The effect on fertility is striking: FROH equivalent to the offspring of first cousins is associated with a 55% decrease [95% CI 44–66%] in the odds of having children. Finally, the effects of FROH are confirmed within full-sibling pairs, where the variation in FROH is independent of all environmental confounding.
4.	Winkler, TW, et al. (author) Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study 2016 In: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404 .- 1553-7390. ; 12:6, s. e1006166- Journal article (peer-reviewed)
5.	Winkler, TW, et al. (author) The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study 2015 In: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404 .- 1553-7390. ; 11:10, s. e1005378- Journal article (peer-reviewed)
6.	Linner, RK, et al. (author) Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences 2019 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 51:2, s. 245- Journal article (peer-reviewed)
7.	Tin, A, et al. (author) Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels 2019 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 51:10, s. 1459- Journal article (peer-reviewed)
8.	Bentley, AR, et al. (author) Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids 2019 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 51:4, s. 636- Journal article (peer-reviewed)
9.	Evangelou, E, et al. (author) Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits 2018 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 50:12, s. 1755-1755 Journal article (peer-reviewed)
10.	Warren, HR, et al. (author) Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk 2017 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 49:3, s. 403-415 Journal article (peer-reviewed)

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Type of publication: journal article (53); conference paper (1); research review (1)

Type of content: peer-reviewed (53); other academic/artistic (2)

Author/Editor: Metspalu, A (18); Esko, T (17); Uitterlinden, AG (16); Psaty, BM (15); Gieger, C (15); Hayward, C. (15); show more...; van Duijn, CM (14); Smith, AV (14); Gudnason, V (14); Polašek, O. (14); Rudan, I. (14); Boerwinkle, E (13); Wareham, NJ (13); Milani, L (13); Langenberg, C. (12); Amin, N (12); Teumer, A (12); Lehtimaki, T. (12); Scott, RA (12); Elliott, Paul (12); Hottenga, JJ (11); Boomsma, DI (11); Hofman, A (11); Rotter, JI (11); Martin, NG (11); Launer, LJ (11); Franks, Paul W. (11); Vollenweider, P. (11); Campbell, H (11); Campbell, A (11); Wilson, JF (11); Metspalu, Andres (11); Peters, A (10); Mahajan, A. (10); Loos, RJF (10); Lind, Lars (10); Montgomery, GW (10); Laakso, Markku (10); Nolte, IM (10); Kutalik, Z. (10); Snieder, H. (10); Boehnke, Michael (10); Mohlke, Karen L (10); Rotter, Jerome I. (10); Stefansson, K (10); Kolcic, I. (10); Zhao, JH (10); Spector, TD (10); Loos, Ruth J F (10); Hayward, Caroline (10); show less...

University: Karolinska Institutet (45); Lund University (20); Uppsala University (18); Umeå University (15); University of Gothenburg (6); Stockholm School of Economics (2); show more...; Högskolan Dalarna (2); Stockholm University (1); Örebro University (1); Malmö University (1); Mid Sweden University (1); show less...

Language: English (56)

Research subject (UKÄ/SCB): Medical and Health Sciences (27); Natural sciences (4)

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