| 1. |
- Smith, Jennifer A, et al.
(author)
-
Genome-wide association study identifies 74 loci associated with educational attainment
- 2016
-
In: Nature (London). - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 533:7604, s. 539-542
-
Journal article (peer-reviewed)abstract
- Educational attainment is strongly influenced by social and other environmental factors, but genetic factors are estimated to account for at least 20% of the variation across individuals. Here we report the results of a genome-wide association study (GWAS) for educational attainment that extends our earlier discovery sample of 101,069 individuals to 293,723 individuals, and a replication study in an independent sample of 111,349 individuals from the UK Biobank. We identify 74 genome-wide significant loci associated with the number of years of schooling completed. Single-nucleotide polymorphisms associated with educational attainment are disproportionately found in genomic regions regulating gene expression in the fetal brain. Candidate genes are preferentially expressed in neural tissue, especially during the prenatal period, and enriched for biological pathways involved in neural development. Our findings demonstrate that, even for a behavioural phenotype that is mostly environmentally determined, a well-powered GWAS identifies replicable associated genetic variants that suggest biologically relevant pathways. Because educational attainment is measured in large numbers of individuals, it will continue to be useful as a proxy phenotype in efforts to characterize the genetic influences of related phenotypes, including cognition and neuropsychiatric diseases.
|
|
| 2. |
- Lee, James J, et al.
(author)
-
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
- 2018
-
In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 50:8, s. 1112-1121
-
Journal article (peer-reviewed)abstract
- Here we conducted a large-scale genetic association analysis of educational attainment in a sample of approximately 1.1million individuals and identify 1,271independent genome-wide-significant SNPs. For the SNPs taken together, we found evidence of heterogeneous effects across environments. The SNPs implicate genes involved in brain-development processes and neuron-to-neuron communication. In a separate analysis of the X chromosome, we identify 10independent genome-wide-significant SNPs and estimate a SNP heritability of around 0.3% in both men and women, consistent with partial dosage compensation. A joint (multi-phenotype) analysis of educational attainment and three related cognitive phenotypes generates polygenic scores that explain 11-13% of the variance in educational attainment and 7-10% of the variance in cognitive performance. This prediction accuracy substantially increases the utility of polygenic scores as tools in research.
|
|
| 3. |
- Björk, Jennie, et al.
(author)
-
The What, Who, When, Where, and How of Idea Assessment.
- 2016
-
Conference paper (other academic/artistic)abstract
- In contemporary innovation management literature there is limitedcomprehensive understanding regarding how different domains andfactors affect and bias early assessment of new product/service ideas.This paper aims at reviewing domains that previous research hasidentified affecting the evaluation of an idea and compiles them into aconceptual framework, and to test this framework among leading expertsand practitioners in the field of idea management. Empirical findings fromtwo workshops indicate that the identified domains in the framework areindeed relevant, but that additional aspect are highlighted and recognized by practitioners. We note that a proactive and deliberate approach to idea assessment needs to be carefully designed, attending to all factors in the presented framework in a comprehensive manner, while taking the organization's specific innovation needs and demands into account.
|
|
| 4. |
|
|
| 5. |
- Engen, Marit, et al.
(author)
-
Casting for service innovation : The roles of frontline employees
- 2018
-
In: Creativity and Innovation Management. - Hoboken, New Jersey, USA : John Wiley & Sons. - 0963-1690 .- 1467-8691. ; 27:3, s. 255-269
-
Journal article (peer-reviewed)abstract
- The purpose of this paper is to explore the roles of frontline employees (FLEs) in service innovation processes and how they contribute to these roles. In the literature, FLEs are argued to play an important role in service innovation; however, neither the potential types of roles nor what taking on these potential roles means to FLEs, have previously been studied. This study investigates FLEs' actions in different types of service innovation processes. Based on analyses of eight different service business units, FLEs are identified as having either of two sets of roles: (1) leading roles as idea creators, developers and implementers, or (2) supporting roles as problem reporters, advisors and executors. The analysis provides managers with guidelines which can help them to better utilize FLEs as contributors to service innovation, either as leading or supporting actors. These imply different management challenges, which are discussed. Advice on how to tackle these challenges is given on the basis of the findings.
|
|
| 6. |
- Engen, Marit, et al.
(author)
-
Exploring the role of frontline employees as innovators
- 2015
-
In: Service Industries Journal. - : Informa UK Limited. - 0264-2069 .- 1743-9507. ; 35:6, s. 303-324
-
Journal article (peer-reviewed)abstract
- This article aims for a deeper understanding of front-line employees (FLEs) and their boundary-spanning role in service organizations’ innovation processes from the vantage points of creativity and service innovation theory. It explores in particular FLEs’ processes of creativity by focusing on how ideas emerge and how these ideas are further managed in the organizations’ innovation processes. It draws on an in-depth empirical study of three units at a large spa and resort hotel. The article demonstrates how FLEs’ ideas are related to the assimilation and utilization of knowledge gained in the customer–supplier interface. Furthermore, it introduces the concept of ‘management by weaving’, which encompasses the middle managers’ roles in the complexity of leading diverse innovation processes in the service organization. By having the roles of facilitator, gatekeeper, and translator, middle managers hold the key position for letting FLEs play the role as innovators.
|
|
| 7. |
- Kristensson, Per, et al.
(author)
-
Introduction
- 2019. - 1
-
In: Service innovation for sustainable business<em> </em>. - New Jersey : World Scientific. - 9789813273375 - 9789813273382 ; , s. 1-14
-
Book chapter (peer-reviewed)
|
|
| 8. |
- Kristensson, Per, et al.
(author)
-
Servitization goes to the psychologist
- 2019
-
In: Service Innovation for Sustainable Business. - New Jersey : World Scientific. - 9789813273382 - 9789813273375 ; , s. 163-177
-
Book chapter (other academic/artistic)abstract
- The following sections are included: Introduction The Platform to Servitization Five Techniques to Start and Perpetuate Change Perpetuating the Change Using the Five Techniques in Change Projects References
|
|
| 9. |
|
|
| 10. |
- Magnusson, Peter, 1960-, et al.
(author)
-
Exploring patients as contributors to service innovation in primary healthcare.
- 2017
-
Conference paper (other academic/artistic)abstract
- This paper investigates the contribution of involving patients for ideation of service innovation in the healthcare context by addressing the following two main research questions: (Q1) What can patients contribute with when invited to contribute with new ideas for improving primary care? and (Q2) How should patient involvement be managed – should they be involved with, or without, healthcare employee involvement? The research questions were addressed by a one-year longitudinal study of ‘innovation groups’ aimed at creating ideas to improve primary care centers. A longitudinal quasi-experimental approach was deployed consisting of three different settings with varying composition of the innovation group: 1) only healthcare employees, 2) only patients, 3) a mix of healthcare employees and patients. In total 180 ideas for service innovation were reported and assessed by four experienced experts using a web-based questionnaire including 8 assessment dimensions and a free text space, inviting the experts to comment on the idea. In addition, individual interviews were conducted which served the purpose of exploring healthcare employees’ value creation when generating ideas together with patients. The study shows that patient involvement during service innovation ideation brings a patient perspective to healthcare. The findings reveal that patient–healthcare employee interactions positively contribute to healthcare employees’ use knowledge as they started to refocus their ideas more towards the patient perspective. Further the study contributes by showing that patient involvement needs to be a focused and dedicated activity towards innovation as, for example, an innovation group, to bring a patient perspective during idea creation.
|
|
