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- West, Jay B., et al.
(author)
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Comparison and evaluation of retrospective intermodality image registration techniques
- 1997
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In: SPIE - The International Society for Optical Engineering. - : SPIE - International Society for Optical Engineering. ; , s. 332-347
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Conference paper (peer-reviewed)abstract
- All retrospective image registration methods have attached to them some intrinsic estimate of registration error. However, this estimate of accuracy may not always be a good indicator of the distance between actual and estimated positions of targets within the cranial cavity. This paper describes a project whose principal goal is to use a prospective method based on fiducial markers as a ’gold standard’ to perform an objective, blinded evaluation of the accuracy of several retrospective image-to-image registration techniques. Image volumes of three modalities – CT, MR, and PET – were taken of patients undergoing neurosurgery at Vanderbilt University Medical Center. These volumes had all traces of the fiducial markers removed, and were provided to project collaborators outside Vanderbilt, who then performed retrospective registrations on the volumes, calculating transformations from CT to MR and/or from PET to MR, and communicated their transformations to Vanderbilt where the accuracy of each registration was evaluated. In this evaluation the accuracy is measured at multiple ’regions of interest,’ i.e. areas in the brain which would commonly be areas of neurological interest. A region is defined in the MR image and its centroid C is determined. Then the prospective registration is used to obtain the corresponding point C’ in CT or PET. To this point the retrospective registration is then applied, producing C’ in MR. Statistics are gathered on the target registration error (TRE), which is the disparity between the original point C and its corresponding point C’. A second goal of the project is to evaluate the importance of correcting geometrical distortion in MR images, by comparing the retrospective TRE in the rectified images, i.e., those which have had the distortion correction applied, with that of the same images before rectification. This paper presents preliminary results of this study along with a brief description of each registration technique and an estimate of both preparation and execution time needed to perform the registration.
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- Aitken, Candice L., et al.
(author)
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Comparison of three methods used for fusion of SPECT-CT images of liver matastases
- 1998
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In: Fusion98, International Conference on Multisource-Mulltisensor Information Fusion. - : CSREA Press. - 1892512009 ; , s. 435-442
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Conference paper (peer-reviewed)abstract
- We compare three methods for fusing SPECT-CT images: ImageMatch - an automatic three-dimensional/two-dimensional method developed by Focus Imaging; IBM Visualization Data Explorer - a three-diemensional interactive method developed by Internation Business Machines, Inc.; and qsh - an interactive three-dimensional/two-dimensional method developed at New York University. While many fusion methods have proved successful for registering brain images, most methods have been less successful for thoracic and abdominal images. We use images of liver metastases obtained with a radiolabeled breast tumor-directed antibody to illustrate the strengths and weakness of the methods reviewed. The images used are typical clinical images from eigth patients. We conclude that an optimal image fusion program should combine the strengths of each of the methods reviewed.
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- Beadle, H.W.P., et al.
(author)
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Location Aware Mobile Computing
- 1997
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In: Proceedings of ICT '97. - : IEEE. ; , s. 1319-1324
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Conference paper (peer-reviewed)
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- Beadle, H.W.P., et al.
(author)
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Using location and environment awareness in mobile communications
- 1997
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In: Proceedings of the International Conference on Information, Communications and Signal Processing, ICICS. - : IEEE. ; , s. 1781-1785
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Conference paper (peer-reviewed)abstract
- We are investigating the use of badge based wearable computers to create highly mobile location and environment aware systems. When coupled to intelligent servers the badges provide an unparalleled platform for human centred information environments. This paper describes the architecture of the badge, its distributed computing environment, and presents initial results of application development trials conducted by a class of telecommunications students at KTH.
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- Farrell, Edward J., et al.
(author)
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Graphical 3D medical image registration and quantification
- 1997
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In: Journal of medical systems. - 0148-5598 .- 1573-689X. ; 21:3, s. 155-172
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Journal article (peer-reviewed)abstract
- We present a graphical three-dimensional method that facilitates image registration and fusion, and provides quantitative geometric and volume information. In particular it enhances the use of functional (radiopharmaceutical) imaging {(SPECT}, {PET)} which, though a powerful clinical tool, has the disadvantage of low spatial resolution and ill-defined boundaries. Registration between functional images and structural images {(MRI}, {CT)} can augment the anatomical context of these functional images.
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- Galvin, J. M., et al.
(author)
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Warping CT scans from nontreatment to treatment position
- 1997
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In: Radiation oncology investigations (Print). - 1065-7541 .- 1520-6823. ; 5:4, s. 206-212
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Journal article (peer-reviewed)abstract
- This paper describes a cost-effective technique that optimally utilizes all available diagnostic studies for three-dimensional treatment planning. A simulator unit modified to produce cross-sectional images {(simulator-CT} unit) is used to create a reference data set with the patient in the treatment position. Registration software (qsh) brings other diagnostic studies into agreement with this reference data set. Two cases are presented as examples of the use of this technique. Registration of abdominal scans from the same patient demonstrates the warping of a nontreatment position study to the treatment position. The second case is based on paired data sets through the head, in which the diagnostic study was obtained by using a gantry tilt to follow the base of the skull and to avoid sections passing through the teeth. The registration software provides a method for combining diagnostic studies into a single "master" data set. The success of the transformation depends on the operator's ability to identify corresponding anatomic landmarks for different data sets and on the magnitude of the variation in the patient's position from one procedure to the next. Limitations in image quality and the number of cross-sections obtainable from a {simulator-CT} unit can be partially overcome by using the described technique. Thus, the information contained in nontreatment position diagnostic tests can be used accurately for treatment planning at limited cost.
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