| 1. |
- Accomando, E., et al.
(author)
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Physics with e + e - linear colliders
- 1998
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In: Physics Reports. - 0370-1573. ; 299:1, s. 1-78
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Journal article (peer-reviewed)abstract
- The physics potential of e + e - linear colliders is summarized in this report. These machines are planned to operate in the first phase at a center-of-mass energy of 500 GeV, before being scaled up to about 1 TeV. In the second phase of the operation, a final energy of about 2 TeV is expected. The machines will allow us to perform precision tests of the heavy particles in the Standard Model, the top quark and the electroweak bosons. They are ideal facilities for exploring the properties of Higgs particles, in particular in the intermediate mass range. New vector bosons and novel matter particles in extended gauge theories can be searched for and studied thoroughly. The machines provide unique opportunities for the discovery of particles in supersymmetric extensions of the Standard Model, the spectrum of Higgs particles, the supersymmetric partners of the electroweak gauge and Higgs bosons, and of the matter particles. High precision analyses of their properties and interactions will allow for extrapolations to energy scales close to the Planck scale where gravity becomes significant. In alternative scenarios, i.e. compositeness models, novel matter particles and interactions can be discovered and investigated in the energy range above the existing colliders up to the TeV scale. Whatever scenario is realized in Nature, the discovery potential of e + e - linear colliders and the high precision with which the properties of particles and their interactions can be analyzed, define an exciting physics program complementary to hadron machines.
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| 2. |
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| 3. |
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| 4. |
- Gadea, A., et al.
(author)
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Spectroscopy at N=Z with EUROBALL III
- 1999
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In: AIP Conference Proceedings. - : AIP. - 1551-7616 .- 0094-243X. ; 495, s. 195-198
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Conference paper (peer-reviewed)abstract
- A complete study of the nuclear structure by means of gamma spectroscopy requires, in addition to the high resolution gamma measurement and accurate DCO's or angular distributions, the information concerning the Electric or Magnetic character of the transition. This information for transitions in nuclei far from stability valley is now reachable in the new generation of Ge-arrays based in composite detectors. EUROBALL III is a good example with the high polarization sensitivity of the 90 degrees ring of Clovers. The Polarization correlations PCO's measured in coincidence with the Cluster detectors permits to investigate transitions in weakly populated nuclei. In this contribution we present results on medium mass N=Z nuclei measured with EUROBALL III coupled with light particle ancillary detectors.
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| 5. |
- De Angelis, G., et al.
(author)
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Collective Excitations in the Vicinity of N=Z
- 1999. - 1 SUPPL. 1
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In: Proceedings INPC 1998. - 0375-9474. ; 654, s. 659-662
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Conference paper (peer-reviewed)abstract
- In our contribution to the INPC98 conference we reported on the experimental investigation of high spin collective states in medium and heavy mass N≈Z nuclei at LNL. The main purpose is to set light on the role of the proton-neutron interaction in the collective behavior of the nucleus. In medium mass N=Z nuclei, in contrast with the stable nuclei, valence protons and neutrons occupy the same orbitals and one may expect a reinforcement of neutron-proton T=0 (np) pairing correlations[1]. In this interesting subject, the medium mass N=Z=36 72Kr has been studied and completely reported in [2]. In this proceedings we will concentrate in unpublished results concerning the onset of collectivity on nearly spherical nuclei in the 100Sn region. In nuclei with Z=50 and Z=49 dipole bands have been found indicating the presence of "Magnetic Rotation" [3].
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| 6. |
- de, Angelis G, et al.
(author)
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T=0 pairing correlations and band crossing phenomena in N=Z nuclei
- 1998
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In: NUCLEAR PHYSICS A. - : ELSEVIER SCIENCE BV. ; 630:1-2, s. 426C-433C
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Journal article (other academic/artistic)abstract
- The structure of the N=Z nuclei Zn-60, Ga-62, Ge-64 and Kr-72 has been investigated at GASP spectrometer through the S-32 + Ca-40 and Ca-40 + Ca-40 reactions at 140 and 160 MeV, respectively, using reaction channel selection with the ISIS Si-ball. The hig
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| 7. |
- Marques, F. M., et al.
(author)
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Neutrons from the breakup of C-19
- 1996
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In: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - 0370-2693. ; 381:4, s. 407-412
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Journal article (peer-reviewed)abstract
- Neutrons arising from the breakup of a 30 MeV/nucleon C-19 beam on a tantalum target have been measured using the 98 element array DEMON. A narrow, forward peaked neutron angular distribution, with a corresponding momentum spread considerably smaller than those measured simultaneously for N-21, O-22 and F-24 was observed for charged fragments with Z
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| 8. |
- Carella, A.M., et al.
(author)
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Mobilization of Philadelphia-negative peripheral blood progenitor cells with chemotherapy and rhuG-CSF in chronic myelogenous leukaemia patients with a poor response to interferon-alpha
- 1998
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In: British Journal of Haematology. - : Wiley. - 0007-1048 .- 1365-2141. ; 101:1, s. 111-8
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Journal article (peer-reviewed)abstract
- The purpose of this cooperative study was to evaluate the quantity and quality of Ph1-negative progenitor cells mobilized in the peripheral blood of patients with chronic myelogenous leukaemia soon after aplasia induced by chemotherapy. 32 patients ineligible for allografting who were cytogenetically refractory to interferon-alpha (IFN-alpha) were entered into this study. The chronic phase varied widely, with a median duration of 17 months (range 3-90 months). All patients were treated with intensive conventional chemotherapy regimens and recombinant human granulocyte colony-stimulating factor (rhuG-CSF, lenograstim). Peripheral blood progenitor cells (PBPC) were harvested by leukaphereses during early recovery from chemotherapy-induced aplasia. A total of 119 leukaphereses were performed. Median numbers of CD34+ cells and CFU-GM collected were 2.04 x 10(6)/kg and 2 9 x 10(4)/kg, respectively. There was a significant correlation between white cell count and number of CD34+ cells in the leukaphereses (P = 0.0001, r2 = 0.41, n = 104). A strict correlation between the number of CD34+ cells and CFU-GM in the leukapheretic product (P = 0.0001, r2 = 0.39, n = 110) was observed. 21% of evaluable patients (6/29) achieved a complete cytogenetic remission in the leukapheretic product and the other four patients achieved a major cytogenetic response for an overall response of 35% (10/22 patients). To date, 16 patients have been autografted and are alive. Five of them are Ph1-negative (three patients) or partially Ph1-negative (two patients). In conclusion, despite the high-risk characteristics of this study population, Ph1-negative PBPC were successfully mobilized in more than one-quarter of patients using a chemotherapy plus rhuG-CSF regimen. The importance of this achievement is increased by the current lack of other practical methods of rescuing Ph-negative cells in such patients.
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| 9. |
- de, Angelis G, et al.
(author)
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Band crossing phenomena in N = Z nuclei - A probe to T = 0 pairing correlations?
- 1997
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In: ACTA PHYSICA HUNGARICA NEW SERIES-HEAVY ION PHYSICS. - : AKADEMIAI KIADO. ; 6:1-4, s. 269-273
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Journal article (other academic/artistic)abstract
- The structure of the N = Z nuclei Zn-60, Ga-62, Ge-64 and Kr-72 has been investigated at GASP. Total Routhian surface (TRS) calculations have been performed for the N = 36, 38 and 40 Kr isotones. In the case of Kr-72 the four quasi-particle g(9/2) alignme
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| 10. |
- Padilla, C. A., et al.
(author)
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Purification from placenta, amino acid sequence, structure comparisons and cDNA cloning of human glutaredoxin
- 1995
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In: European Journal of Biochemistry. - : Wiley-Blackwell. - 0014-2956 .- 1432-1033. ; 227:1-2, s. 27-34
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Journal article (peer-reviewed)abstract
- Glutaredoxin is generally a glutathione-dependent hydrogen donor for ribonucleotide reductase and also catalyses general glutathione (GSH)-disulfide-oxidoreduction reactions in the presence of NADPH and glutathione reductase. A Glutaredoxin from human placenta was purified to homogeneity, as judged by SDS/PAGE and IEF (12 kDa). Purification was monitored by the activity with hydroxyethyl disulfide as a substrate. Values of pI for glutaredoxin were obtained by IEF; the pI of the protein shifted from 7.3 in its fully reduced state to 9.0 in the oxidized state after treatment with excess hydroxyethyl disulfide. The glutaredoxin preparation showed GSH-dependent hydrogen-donor activity with recombinant mouse ribonucleotide reductase, it exhibited dehydroascorbate reductase activity as well as hydroxyethyl-disulfide-reducing activity. The amino acid sequence (residues 3-104) of glutaredoxin was determined by peptide sequencing and residues 1, 2 and 105 by cDNA sequence analysis. The glutaredoxin sequence comprised the classical active site for glutaredoxins -Cys22-Pro-Tyr-Cys25- and three additional half-cystine residues; two of these in positions 78 and 82. The sequence was similar to other known mammalian glutaredoxins (about 80% identities), with important differences such as one additional Cys residue (Cys7) and no Met residue. The sequence of human glutaredoxin was compared to that of Escherichia coli glutaredoxin with known three-dimensional structure in solution to identify conserved residues and predict a structure from alignment. In particular the GSH-binding site of glutaredoxin was conserved between all molecules. A cDNA that encodes the entire glutaredoxin gene (grx) and flanking sequences was isolated from a human spleen cDNA library. The nucleotide sequence of this cDNA (0.8 kb) was determined, including the complete grx gene.
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