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Träfflista för sökning "WFRF:(Matic Ivan) srt2:(2002-2004)"

Search: WFRF:(Matic Ivan) > (2002-2004)

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1.
  • Denamur, Erick, et al. (author)
  • High frequency of mutator strains among human uropathogenic Escherichia coli isolates.
  • 2002
  • In: Journal of Bacteriology. - 0021-9193 .- 1098-5530. ; 184:2, s. 605-9
  • Journal article (peer-reviewed)abstract
    • By using a panel of 603 commensal and pathogenic Escherichia coli and Shigella isolates, we showed that mutation rates of strains vary considerably among different ecotypes. Uropathogenic strains had the highest frequency of mutators, while strains from patients with bacteremia had the lowest mutation rates. No correlation between the mutation rates and antibiotic resistance was observed among the studied strains.
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2.
  • Giraud, Antoine, et al. (author)
  • Mutator bacteria as a risk factor in treatment of infectious diseases.
  • 2002
  • In: Antimicrobial Agents and Chemotherapy. - 0066-4804 .- 1098-6596. ; 46:3, s. 863-5
  • Journal article (peer-reviewed)abstract
    • We show in a gnotobiotic mouse model that, in addition to direct selection of antibiotic-resistant bacteria, some antibiotic treatments also select for mutator alleles. Because of these mutator alleles' high mutation rates, the initial treatment failure increases the probability of failures in subsequent treatments with other drugs.
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