| 1. |
- Dominguez Perez, Sophia, et al.
(author)
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Neuropsychological and Neuroanatomical Features of Patients with Behavioral/Dysexecutive Variant Alzheimer's Disease (AD) : A Comparison to Behavioral Variant Frontotemporal Dementia and Amnestic AD Groups
- 2022
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In: Journal of Alzheimer's Disease. - 1387-2877. ; 89:2, s. 641-658
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Journal article (peer-reviewed)abstract
- Background: An understudied variant of Alzheimer's disease (AD), the behavioral/dysexecutive variant of AD (bvAD), is associated with progressive personality, behavior, and/or executive dysfunction and frontal atrophy. Objective: This study characterizes the neuropsychological and neuroanatomical features associated with bvAD by comparing it to behavioral variant frontotemporal dementia (bvFTD), amnestic AD (aAD), and subjects with normal cognition. Methods: Subjects included 16 bvAD, 67 bvFTD, 18 aAD patients, and 26 healthy controls. Neuropsychological assessment and MRI data were compared between these groups. Results: Compared to bvFTD, bvAD showed more significant visuospatial impairments (Rey Figure copy and recall), more irritability (Neuropsychological Inventory), and equivalent verbal memory (Philadelphia Verbal Learning Test). Compared to aAD, bvAD indicated more executive dysfunction (F-letter fluency) and better visuospatial performance. Neuroimaging analysis found that bvAD showed cortical thinning relative to bvFTD posteriorly in left temporal-occipital regions; bvFTD had cortical thinning relative to bvAD in left inferior frontal cortex. bvAD had cortical thinning relative to aAD in prefrontal and anterior temporal regions. All patient groups had lower volumes than controls in both anterior and posterior hippocampus. However, bvAD patients had higher average volume than aAD patients in posterior hippocampus and higher volume than bvFTD patients in anterior hippocampus after adjustment for age and intracranial volume. Conclusion: Findings demonstrated that underlying pathology mediates disease presentation in bvAD and bvFTD.
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| 2. |
- Gehrmann, Sebastian, et al.
(author)
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GEMv2: Multilingual NLG Benchmarking in a Single Line of Code
- 2022
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In: Proceedings of the 2022 Conference on Empirical Methods in Natural Language Processing: System Demonstrations. - : Association for Computational Linguistics (ACL). ; , s. 266-281
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Conference paper (peer-reviewed)abstract
- Evaluations in machine learning rarely use the latest metrics, datasets, or human evaluation in favor of remaining compatible with prior work. The compatibility, often facilitated through leaderboards, thus leads to outdated but standardized evaluation practices. We pose that the standardization is taking place in the wrong spot. Evaluation infrastructure should enable researchers to use the latest methods and what should be standardized instead is how to incorporate these new evaluation advances.We introduce GEMv2, the new version of the Generation, Evaluation, and Metrics Benchmark which uses a modular infrastructure for dataset, model, and metric developers to benefit from each other’s work. GEMv2 supports 40 documented datasets in 51 languages, ongoing online evaluation for all datasets, and our interactive tools make it easier to add new datasets to the living benchmark.
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| 3. |
- Mikkola, Daniel, et al.
(author)
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The velocity distribution of white dwarfs in Gaia EDR3
- 2022
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In: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 512:4, s. 6201-6216
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Journal article (peer-reviewed)abstract
- Using a penalized maximum likelihood, we estimate, for the first time, the velocity distribution of white dwarfs in the solar neighbourhood. Our sample consists of 129 675 white dwarfs within 500 pc in Gaia Early Data Release 3. The white dwarf velocity distributions reveal a similar structure to the rest of the solar neighbourhood stars, reflecting that white dwarfs are subject to the same dynamical processes. In the velocity distribution for three magnitude-binned subsamples, we, however, find a novel structure at (U, V) = (7,-19) km s-1 in fainter samples, potentially related to the Coma Berenices stream. We also see a double-peaked feature in U-W at U ≈-30 km s-1 and in V-W at V ≈-20 km s-1 for fainter samples. We determine the velocity distribution and velocity moments as a function of absolute magnitude for two samples based on the bifurcation identified in Gaia Data Release 2 in the colour-magnitude diagram. The brighter, redder sequence has a larger velocity dispersion than the fainter, bluer sequence across all magnitudes. It is hard to reconcile this kinematic difference with a bifurcation caused purely by atmospheric composition, while it fits neatly with a significant age difference between the two sequences. Our results provide novel insights into the kinematic properties of white dwarfs and demonstrate the power of analytical techniques that work for the large fraction of stars that do not have measured radial velocities in the current era of large-scale astrometric surveys.
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| 4. |
- Ripepi, Vincenzo, et al.
(author)
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The VMC survey - XLVIII. Classical cepheids unveil the 3D geometry of the LMC
- 2022
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In: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 512:1, s. 563-582
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Journal article (peer-reviewed)abstract
- We employed the VISTA near-infrared YJKssurvey of the Magellanic System (VMC) to analyse the Y, J, and Ks light curves of δCepheid stars (DCEPs) in the Large Magellanic Cloud (LMC). Our sample consists of 4408 objects accounting for 97 per cent of the combined list of OGLE IV and Gaia DR2 DCEPs. We determined a variety of period-luminosity (PL) and period-Wesenheit PW relationships for Fundamental (F) and First Overtone (1O) pulsators. We discovered for the first time a break in these relationships for 1O DCEPs at P= 0.58 d. We derived relative individual distances for DCEPs in the LMC with a precision of ∼1 kpc, calculating the position angle of the line of nodes and inclination of the galaxy: θ = 145.6 ± 1.0 deg and i = 25.7 ± 0.4 deg. The bar and the disc are seen under different viewing angles. We calculated the ages of the pulsators, finding two main episodes of DCEP formation lasting ∼40 Myr which happened 93 and 159 Myr ago. Likely as a result of its past interactions with the SMC, the LMC shows a non-planar distribution, with considerable structuring: the bar is divided into two distinct portions, the eastern and the western displaced by more than 1 kpc from each other. Similar behaviour is shown by the spiral arms. The LMC disc appears 'flared' and thick, with a disc scale height of h ∼0.97 kpc. This feature can be explained by strong tidal interactions with the Milky Way and/or the Small Magellanic Cloud or past merging events with now disrupted LMC satellites.
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