| 1. |
- de Jong, R. S., et al.
(author)
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4MOST : Project overview and information for the First Call for Proposals
- 2019
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In: The Messenger. - : European Southern Observatory. - 0722-6691. ; 175, s. 3-11
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Journal article (other academic/artistic)abstract
- We introduce the 4-metre Multi-Object Spectroscopic Telescope (4MOST), a new high-multiplex, wide-field spectroscopic survey facility under development for the four-metre-class Visible and Infrared Survey Telescope for Astronomy (VISTA) at Paranal. Its key specifications are: a large field of view (FoV) of 4.2 square degrees and a high multiplex capability, with 1624 fibres feeding two low-resolution spectrographs (R = λ/Δλ ~ 6500), and 812 fibres transferring light to the high-resolution spectrograph (R ~ 20 000). After a description of the instrument and its expected performance, a short overview is given of its operational scheme and planned 4MOST Consortium science; these aspects are covered in more detail in other articles in this edition of The Messenger. Finally, the processes, schedules, and policies concerning the selection of ESO Community Surveys are presented, commencing with a singular opportunity to submit Letters of Intent for Public Surveys during the first five years of 4MOST operations.
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| 2. |
- Navarrini, A., et al.
(author)
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Design of PHAROS2 Phased Array Feed
- 2018
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In: 2018 2nd URSI Atlantic Radio Science Meeting, AT-RASC 2018.
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Conference paper (peer-reviewed)abstract
- We describe the design and architecture of PHAROS2, a cryogenically cooled 4-8 GHz Phased Array Feed (PAF) demonstrator with digital beamformer for radio astronomy application. The instrument will be capable of synthesizing four independent single-polarization beams by combining 24 active elements of an array of Vivaldi antennas. PHAROS2, the upgrade of PHAROS (PHased Arrays for Reflector Observing Systems), features: a) commercial cryogenic LNAs with state-of-the-art performance, b) a 'Warm Section' for signal filtering, conditioning and single downconversion to select a≈275 MHz: Intermediate Frequency (IF) bandwidth within the 4-8 GHz Radio Frequency (RF) band, c) an IF signal transportation by analog WDM (Wavelength Division Mutiplexing) fiber-optic link, and d) a FPGA-based Italian Tile Processing Module (iTPM) digital backend. PHAROS2 will be mounted at the primary focus of the 76-m diameter Lovell radio telescope (Jodrell Bank Observatory, UK) for technical and scientific validation.
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| 3. |
- Carrillo, I., et al.
(author)
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Is the Milky Way still breathing? RAVE-Gaia streaming motions
- 2018
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In: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 475:2, s. 2679-2696
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Journal article (peer-reviewed)abstract
- We use data from the Radial Velocity Experiment (RAVE) and the Tycho-Gaia astrometric solution (TGAS) catalogue to compute the velocity fields yielded by the radial (V-R), azimuthal (V-phi), and vertical (V-z) components of associated Galactocentric velocity. We search in particular for variation in all three velocity components with distance above and below the disc midplane, as well as how each component of V-z (line-of-sight and tangential velocity projections) modifies the obtained vertical structure. To study the dependence of velocity on proper motion and distance, we use two main samples: a RAVE sample including proper motions from the Tycho-2, PPMXL, and UCAC4 catalogues, and a RAVE-TGAS sample with inferred distances and proper motions from the TGAS and UCAC5 catalogues. In both samples, we identify asymmetries in V-R and V-z. Below the plane, we find the largest radial gradient to be partial derivative V-R/partial derivative R = -7.01 +/- 0.61 km s(-1) kpc(-1), in agreement with recent studies. Above the plane, we find a similar gradient with partial derivative V-R/partial derivative R = -9.42 +/- 1.77 km s(-1) kpc(-1). By comparing our results with previous studies, we find that the structure in V-z is strongly dependent on the adopted proper motions. Using the Galaxia Milky Way model, we demonstrate that distance uncertainties can create artificial wave-like patterns. In contrast to previous suggestions of a breathing mode seen in RAVE data, our results support a combination of bending and breathing modes, likely generated by a combination of external or internal and external mechanisms.
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| 4. |
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| 5. |
- Antoja, T., et al.
(author)
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Asymmetric metallicity patterns in the stellar velocity space with RAVE
- 2017
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In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 601
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Journal article (peer-reviewed)abstract
- Context. The chemical abundances of stars encode information on their place and time of origin. Stars formed together in e.g. a cluster, should present chemical homogeneity. Also disk stars influenced by the effects of the bar and the spiral arms might have distinct chemical signatures depending on the type of orbit that they follow, e.g. from the inner versus outer regions of the Milky Way.Aims. We explore the correlations between velocity and metallicity and the possible distinct chemical signatures of the velocity over-densities of the local Galactic neighbourhood.Methods. We use the large spectroscopic survey RAVE and the Geneva Copenhagen Survey. We compare the metallicity distribution of regions in the velocity plane (upsilon(R), upsilon(phi)) with that of their symmetric counterparts (-upsilon(R), upsilon(phi)). We expect similar metallicity distributions if there are no tracers of a sub-population (e.g. a dispersed cluster, accreted stars), if the disk of the Galaxy is axisymmetric, and if the orbital effects of the bar and the spiral arms are weak.Results. We find that the metallicity-velocity space of the solar neighbourhood is highly patterned. A large fraction of the velocity plane shows differences in the metallicity distribution when comparing symmetric upsilon(R) regions. The typical differences in the median metallicity are of 0 : 05 dex with statistical significant of at least 95% confidence, and with values up to 0 : 6 dex. For stars with low azimuthal velocity v(phi), the ones moving outwards. These include stars in the Hercules and Hyades moving groups and other velocity branch-like structures. For higher v(phi), the stars moving inwards have higher metallicity than those moving outwards. We have also discovered a positive gradient in v(phi) with resp ect to metallicity at high metallicities, apart from the two known positive and negative gradients for the thick and thin disks.Conclusions. The most likely interpretation of the metallicity asymmetry is that it is mainly due to the orbital effects of the Galactic bar and the radial metallicity gradient of the disk. We present a simulation that supports this idea.
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| 6. |
- Carrillo, I., et al.
(author)
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Kinematics with GAIA DR2 : The force of a dwarf
- 2019
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In: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 1365-2966 .- 0035-8711. ; 490:1, s. 797-812
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Journal article (peer-reviewed)abstract
- We use Gaia DR2 astrometric and line-of-sight velocity information combined with two sets of distances obtained with a Bayesian inference method to study the 3D velocity distribution in the Milky Way disc. We search for variations in all Galactocentric cylindrical velocity components (Vφ, VR, and Vz) with Galactic radius, azimuth, and distance from the disc mid-plane. We confirm recent work showing that bulk vertical motions in the R–z plane are consistent with a combination of breathing and bending modes. In the x–y plane, we show that, although the amplitudes change, the structure produced by these modes is mostly invariant as a function of distance from the plane. Comparing to two different Galactic disc models, we demonstrate that the observed patterns can drastically change in short time intervals, showing the complexity of understanding the origin of vertical perturbations. A strong radial VR gradient was identified in the inner disc, transitioning smoothly from 16 km s−1 kpc−1 at an azimuth of 30◦ < φ < 45◦ ahead of the Sun-Galactic centre line to −16 km s−1 kpc−1 at an azimuth of −45◦ < φ < −30◦ lagging the solar azimuth. We use a simulation with no significant recent mergers to show that exactly the opposite trend is expected from a barred potential, but overestimated distances can flip this trend to match the data. Alternatively, using an N-body simulation of the Sagittarius dwarf–Milky Way interaction, we demonstrate that a major recent perturbation is necessary to reproduce the observations. Such an impact may have strongly perturbed the existing bar or even triggered its formation in the last 1–2 Gyr.
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| 7. |
- Navarrete-Miguel, M., et al.
(author)
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Quantum chemistry of the excited state : Recent trends in methods developments and applications
- 2019
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In: Photochemistry. - Cambridge : Royal Society of Chemistry. - 1465-1947. - 9781788013369 ; , s. 28-77
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Book chapter (peer-reviewed)abstract
- Advances (2016-2017) in Quantum Chemistry of the Excited State (QCEX) are presented in this book chapter focusing firstly on developments of methodology and excited-state reaction-path computational strategies and secondly on the applications of QCEX to study light-matter interaction in distinct fields of biology, (nano)-technology, medicine and the environment. We highlight in this contribution developments of static and dynamic electron-correlation methods and methodological approaches to determine dynamical properties, recent examples of the roles of conical intersections, novel DNA spectroscopy and photochemistry findings, photo-sensitisation mechanisms in biological structures and the current knowledge on chemi-excitation mechanisms that give rise to light emission (in the chemiluminescence and bioluminescence phenomena).
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| 8. |
- Bignon, E., et al.
(author)
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Ibuprofen and ketoprofen potentiate UVA-induced cell death by a photosensitization process
- 2017
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In: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 7
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Journal article (peer-reviewed)abstract
- Nonsteroidal 2-arylproprionic acids are widely used, over-the-counter, anti-inflammatory drugs. Photosensitivity is a commonly overlooked adverse effect of these drugs. Based on the combined use of cell viability assays and molecular modeling, we prove and rationalize the photochemical pathways triggering photosensitization for two drugs, ibuprofen and ketoprofen. As its parent compound benzophenone, ketoprofen produces singlet oxygen, upon triplet manifold population. However, ibuprofen and ketoprofen photodissociate and hence may generate two highly reactive radicals. The formation of metastable aggregates between the two drugs and B-DNA is also directly probed by molecular dynamics. Our approach characterizes the coupled influence of the drug's intrinsic photochemistry and the interaction pattern with DNA. The photosensitization activity of nonsteroidal 2-arylproprionic acids, being added to gels and creams for topical use, should be crucially analyzed and rationalized to enact the proper preventive measures.
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| 9. |
- Martinez-Ramirez, Daniel, et al.
(author)
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Efficacy and Safety of Deep Brain Stimulation in Tourette Syndrome : The International Tourette Syndrome Deep Brain Stimulation Public Database and Registry
- 2018
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In: JAMA Neurology. - : American Medical Association. - 2168-6149 .- 2168-6157. ; 75:3, s. 353-359
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Journal article (peer-reviewed)abstract
- IMPORTANCE Collective evidence has strongly suggested that deep brain stimulation (DBS) is a promising therapy for Tourette syndrome.OBJECTIVE To assess the efficacy and safety of DBS in a multinational cohort of patients with Tourette syndrome.DESIGN, SETTING, AND PARTICIPANTS The prospective International Deep Brain Stimulation Database and Registry included 185 patients with medically refractory Tourette syndrome who underwent DBS implantation from January 1, 2012, to December 31, 2016, at 31 institutions in 10 countries worldwide.EXPOSURES Patients with medically refractory symptoms received DBS implantation in the centromedian thalamic region (93 of 163 [57.1%]), the anterior globus pallidus internus (41 of 163 [25.2%]), the posterior globus pallidus internus (25 of 163 [15.3%]), and the anterior limb of the internal capsule (4 of 163 [2.5%]).MAIN OUTCOMES AND MEASURES Scores on the Yale Global Tic Severity Scale and adverse events.RESULTS The International Deep Brain Stimulation Database and Registry enrolled 185 patients (of 171 with available data, 37 females and 134 males; mean [SD] age at surgery, 29.1 [10.8] years [range, 13-58 years]). Symptoms of obsessive-compulsive disorder were present in 97 of 151 patients (64.2%) and 32 of 148 (21.6%) had a history of self-injurious behavior. The mean (SD) total Yale Global Tic Severity Scale score improved from 75.01 (18.36) at baseline to 41.19 (20.00) at 1 year after DBS implantation (P<.001). The mean (SD) motor tic subscore improved from 21.00 (3.72) at baseline to 12.91 (5.78) after 1 year (P <.001), and the mean (SD) phonic tic subscore improved from 16.82 (6.56) at baseline to 9.63 (6.99) at 1 year (P <.001). The overall adverse event rate was 35.4%(56 of 158 patients), with intracranial hemorrhage occurring in 2 patients (1.3%), infection in 4 patients with 5 events (3.2%), and lead explantation in 1 patient (0.6%). The most common stimulation-induced adverse effects were dysarthria (10 [6.3%]) and paresthesia (13 [8.2%]).CONCLUSIONS AND RELEVANCE Deep brain stimulationwas associated with symptomatic improvement in patients with Tourette syndrome but also with important adverse events. A publicly available website on outcomes of DBS in patients with Tourette syndrome has been provided.
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| 10. |
- Monari, Giacomo, et al.
(author)
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Tracing the Hercules stream with Gaia and LAMOST : new evidence for a fast bar in the Milky Way
- 2017
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In: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966 .- 1745-3925 .- 1745-3933. ; 466:1, s. l113-L117
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Journal article (peer-reviewed)abstract
- The length and pattern speed of the Milky Way bar are still controversial. Photometric and spectroscopic surveys of the inner Galaxy, as well as gas kinematics, favour a long and slowly rotating bar, with corotation around a Galactocentric radius of 6 kpc. On the other hand, the existence of the Hercules stream in local velocity space favours a short and fast bar with corotation around 4 kpc. This follows from the fact that the Hercules stream looks like a typical signature of the outer Lindblad resonance of the bar. As we showed recently, reconciling this local stream with a slow bar would need to find a yet unknown alternative explanation, based, for instance, on the effect of spiral arms. Here, by combining the TGAS catalogue of the Gaia DR1 with LAMOST radial velocities, we show that the position of Hercules in velocity space as a function of radius in the outer Galaxy indeed varies exactly as predicted by fast bar models with a pattern speed no less than 1.8 times the circular frequency at the Sun's position.
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