SwePub
Sök i SwePub databas

  Extended search

Träfflista för sökning "WFRF:(Morelli A) "

Search: WFRF:(Morelli A)

  • Result 1-10 of 57
Sort/group result
   
EnumerationReferenceCoverFind
1.
  • 2021
  • swepub:Mat__t
  •  
2.
  • Bravo, L, et al. (author)
  • 2021
  • swepub:Mat__t
  •  
3.
  • Tabiri, S, et al. (author)
  • 2021
  • swepub:Mat__t
  •  
4.
  • Glasbey, JC, et al. (author)
  • 2021
  • swepub:Mat__t
  •  
5.
  •  
6.
  • 2017
  • swepub:Mat__t
  •  
7.
  •  
8.
  •  
9.
  • de Rojas, I., et al. (author)
  • Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
  • 2021
  • In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 12:1
  • Journal article (peer-reviewed)abstract
    • Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical trials. We first perform a large genetic association study by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190). Here, we add six variants associated with Alzheimer’s disease risk (near APP, CHRNE, PRKD3/NDUFAF7, PLCG2 and two exonic variants in the SHARPIN gene). Assessment of the polygenic risk score and stratifying by APOE reveal a 4 to 5.5 years difference in median age at onset of Alzheimer’s disease patients in APOE ɛ4 carriers. Because of this study, the underlying mechanisms of APP can be studied to refine the amyloid cascade and the polygenic risk score provides a tool to select individuals at high risk of Alzheimer’s disease. © 2021, The Author(s).
  •  
10.
  •  
Skapa referenser, mejla, bekava och länka
  • Result 1-10 of 57
Type of publication
journal article (47)
research review (3)
conference paper (2)
Type of content
peer-reviewed (48)
other academic/artistic (4)
Author/Editor
Giommi, P. (8)
Vercellone, S. (8)
Longo, F. (7)
Colafrancesco, S. (7)
Bulgarelli, A. (7)
Donnarumma, I. (7)
show more...
Pacciani, L. (7)
Costa, E. (7)
Chen, S. (6)
Ferrari, A. (6)
Gianotti, F. (6)
Qureshi, A. (6)
Romano, M. (6)
Martin, J. (6)
Lakkis, Z (6)
Rottoli, M (6)
Moore, R. (6)
Giraudo, G. (6)
Sharma, N. (6)
Singh, R. (6)
Nowak, K. (6)
Costa, M. (6)
O'Brien, S. (6)
Abate, E. (6)
Lee, M (6)
Williams, J (6)
Ali, M (6)
Negoi, I (6)
Salem, H (6)
Singh, A (6)
Desai, A. (6)
Evans, J. (6)
Barbiellini, G. (6)
Morselli, A. (6)
Caraveo, P. (6)
Sharma, P. (6)
Santos, R. (6)
Giuliani, A. (6)
Conti, L. (6)
Picozza, P. (6)
Chen, A. W. (6)
Piano, G. (6)
Pittori, C. (6)
Verrecchia, F. (6)
Sherif, A. (6)
Khan, T. (6)
Pilia, M. (6)
Vallazza, E. (6)
Smith, J. (6)
Trifoglio, M. (6)
show less...
University
Karolinska Institutet (30)
Lund University (11)
Uppsala University (9)
Royal Institute of Technology (8)
Stockholm University (6)
Linköping University (6)
show more...
Umeå University (5)
University of Gothenburg (4)
Swedish University of Agricultural Sciences (3)
Jönköping University (1)
Mid Sweden University (1)
Chalmers University of Technology (1)
show less...
Language
English (57)
Research subject (UKÄ/SCB)
Medical and Health Sciences (23)
Natural sciences (15)
Social Sciences (2)
Engineering and Technology (1)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view