| 1. |
- Skands, Peter, et al.
(author)
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SUSY Les Houches accord: interfacing SUSY spectrum calculators, decay packages, and event generators
- 2004
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In: Journal of High Energy Physics. - 1029-8479. ; :7
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Journal article (peer-reviewed)abstract
- An accord specifying a unique set of conventions for supersymmetric extensions of the Standard Model together with generic file structures for 1) supersymmetric model specifications and input parameters, 2) electroweak scale supersymmetric mass and coupling spectra, and 3) decay tables is presented, to provide a universal interface between spectrum calculation programs, decay packages, and high energy physics event generators.
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| 2. |
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| 3. |
- Boudrioua, A., et al.
(author)
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Nonlinear optical properties of (H+,He+)-implanted planar waveguides in z-cut lithium niobate : annealing effect
- 2001
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In: Journal of the Optical Society of America. B, Optical physics. - 0740-3224 .- 1520-8540. ; 18:12, s. 1832-1840
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Journal article (peer-reviewed)abstract
- Reflection second-harmonic generation from the polished waveguide end face was used to investigate the nonlinear properties of LiNbO3-implanted waveguides fabricated by use of 2-MeV He+ and 1.5-Mev H+ beams. Results were compared with waveguides obtained by protonic exchange in benzoic acid, In contrast to the exchanged sample where the nonlinearity is strongly reduced, the implanted samples showed that the guiding region presents rather the same response as the substrate. The area where the optical barrier is located showed a strongly enhanced second-harmonic signal that was likely to be due to structural modifications in this area. Moreover, the investigation of the annealing effect showed strong interaction of protons with the lattice compared with that of He+ ions.
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| 4. |
- Dedes, A, et al.
(author)
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Effect of large supersymmetric phases on Higgs production
- 2000
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In: PHYSICAL REVIEW LETTERS. - : AMERICAN PHYSICAL SOC. - 0031-9007. ; 84:1, s. 22-25
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Journal article (peer-reviewed)abstract
- If the soft supersymmetry (SUSY) breaking masses and couplings are complex and cancellations do take place in the SUSY induced contributions to the fermionic electric dipole moments, then the CP-violating soft phases can drastically modify much of the kno
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| 5. |
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| 6. |
- Dedes A., Moretti S.
(author)
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New Faces of Supersymmetry: effects of large phases on Higgs production
- 2000
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In: Phys. Rev. Lett.. ; 84, s. 22-25
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Journal article (peer-reviewed)abstract
- If the soft Supersymmetry (SUSY) breaking masses and couplings are complex and cancelations do take place in the SUSY induced contributions to the fermionic Electric Dipole Moments (EDMs), then the CP-violating soft phases can drastically modify much of t
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| 7. |
- Tomasetti, M, et al.
(author)
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α-tocopheryl succinate and TRAIL selectively synergise in induction of apoptosis in human malignant mesothelioma cells
- 2004
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In: British Journal of Cancer. - : Springer Science and Business Media LLC. - 0007-0920 .- 1532-1827. ; 90:8, s. 1644-1653
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Journal article (peer-reviewed)abstract
- Malignant mesothelioma (MM) is a fatal type of neoplasia with poor therapeutic prognosis, largely due to resistance to apoptosis. We investigated the apoptotic effect of α-tocopheryl succinate (α-TOS), a strong proapoptotic agent, in combination with the immunological apoptogen TNF-related apoptosis-inducing ligand (TRAIL) on both MM and nonmalignant mesothelial cells, since MM cells show low susceptibility to the clinically intriguing TRAIL. All MM cell lines tested were sensitive to α-TOS-induced apoptosis, and exerted high sensitivity to TRAIL in the presence of subapoptotic doses of the vitamin E analogue. Neither TRAIL or α-TOS alone or in combination caused apoptosis in nonmalignant mesothelial cells. Isobologram analysis of the cytotoxicity assays revealed a synergistic interaction between the two agents in MM cells and their antagonistic effect in nonmalignant mesothelial cells. TRAIL-induced apoptosis and its augmentation by α-TOS were inhibited by the caspase-8 inhibitor Z-IETD-FMK and the pan-caspase inhibitor Z-VAD-FMK. Activation of caspase-8 was required to induce apoptosis, which was amplified by α-TOS via cytochrome c release following Bid cleavage, with ensuing activation of caspase-9. Enhancement of TRAIL-induced apoptosis in MM cells by α-TOS was also associated with upregulation of the TRAIL cognate death receptors DR4 and DR5. Our results show that α-TOS and TRAIL act in synergism to kill MM cells via mitochondrial pathway, and are nontoxic to nonmalignant mesothelial cells. These findings are indicative of a novel strategy for treatment of thus far fatal MM.
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