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1.	Abu-Youssef, Morsy A. M., et al. (author) Synthesis, Crystal Structure, Quantum Chemical Calculations, DNA Interactions, and Antimicrobial Activity of [Ag(2-amino-3-methylpyridine)2]NO3 and [Ag(pyridine-2-carboxaldoxime)NO3] 2010 In: Inorganic Chemistry. - : American Chemical Society (ACS). - 0020-1669 .- 1520-510X. ; 49:21, s. 9788-9797 Journal article (peer-reviewed)abstract [Ag(2-amino-3-methylpyridine)2]NO3 (1) and [Ag(pyridine-2-carboxaldoxime)NO3] (2) were prepared from corresponding ligands and AgNO3 in water/ethanol solutions, and the products were characterized by IR, elemental analysis, NMR, and TGA. The X-ray crystal structures of the two compounds show that the geometry around the silver(I) ion is bent for complex 1 with nitrate as an anion and trigonal planar for complex 2 with nitrate coordinated. ESI-MS results of solutions of 2 indicate the independent existence in solution of the [Ag(pyridine-2-carboxaldoxime)]+ ion. The geometries of the complexes are well described by DFT calculations using the ZORA relativistic approach. The compounds were tested against 14 different clinically isolated and four ATCC standard bacteria and yeasts and also compared with 17 commonly used antibiotics. Both 1 and 2 exhibited considerable activity against S. lutea, M. lutea, and S. aureus and against the yeast Candida albicans, while 2-amino-3-methylpyridine is slightly active and pyridine-2-carboxaldoxime shows no antimicrobial activity. In addition, the interaction of these metal complexes with DNA was investigated. Both 1 and 2 bind to DNA and reduce its electrophoretic mobility with different patterns of migration, while the ligands themselves induce no change.
2.	Knoll, Greg A, et al. (author) Effect of sirolimus on malignancy and survival after kidney transplantation: systematic review and meta-analysis of individual patient data. 2014 In: BMJ: British Medical Journal. - : BMJ. - 1756-1833. ; 349, s. 6679-6679 Journal article (peer-reviewed)abstract To examine risk of malignancy and death in patients with kidney transplant who receive the immunosuppressive drug sirolimus.

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Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Abu-Youssef, Morsy A ... (1); Langer, Vratislav, 1 ... (1); Öhrström, Lars, 1963 (1); Soliman, S.M. (1); Gohar, Yousry M. (1); Hasanen, Ahmed A. (1); show more...; Makhyoun, Mohamed (1); Zaky, Amira H. (1); Ekberg, Henrik (1); Watson, Christopher (1); Ducharme, Robin (1); Bernasconi, Corrado (1); Tedesco-Silva, Helio (1); Vítko, Stefan (1); Glotz, Denis (1); Fergusson, Dean A. (1); Knoll, Greg A (1); Kokolo, Madzouka B (1); Mallick, Ranjeeta (1); Beck, Andrew (1); Buenaventura, Chieny ... (1); Barsoum, Rashad (1); Blydt-Hansen, Tom D (1); Felipe, Claudia R (1); Firth, John (1); Gallon, Lorenzo (1); Gelens, Marielle (1); Gossmann, Jan (1); Guba, Markus (1); Morsy, Ahmed Ali (1); Salgo, Rebekka (1); Scheuermann, Earnst ... (1); show less...

University: Lund University (1); Chalmers University of Technology (1)

Language: English (2)

Research subject (UKÄ/SCB): Medical and Health Sciences (2); Natural sciences (1)

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