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Träfflista för sökning "WFRF:(Myhr Eriksson Kristina) srt2:(2015-2019)"

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1.	Hjorth-Hansen, Henrik, et al. (author) Safety and Efficacy of Addition of Pegylated Interferon alpha2b to Standard Dose Dasatinib in Newly Diagnosed Chronic Phase CML Patients 2015 In: Blood. - 0006-4971 .- 1528-0020. ; 126:23 Journal article (other academic/artistic)
2.	Juliusson, G., et al. (author) Prevalence and characteristics of survivors from acute myeloid leukemia in Sweden 2017 In: Leukemia. - : Nature Publishing Group. - 0887-6924 .- 1476-5551. ; 31:3, s. 728-731 Journal article (peer-reviewed)
3.	Juliusson, Gunnar, et al. (author) Prevalence and Characteristics of Survivors from Adult Acute Myeloid Leukemia (AML) in Sweden 2014 2015 In: Blood. - 0006-4971 .- 1528-0020. ; 126:23 Journal article (other academic/artistic)
4.	Lehmann, Sören, et al. (author) Early death rates remain high in high-risk APL : update from the Swedish Acute Leukemia Registry 1997-2013 2017 In: Leukemia. - : Nature Publishing Group. - 0887-6924 .- 1476-5551. ; 31:6, s. 1457-1459 Journal article (peer-reviewed)
5.	Machaczka, Maciej, et al. (author) Impact of imiglucerase supply shortage on clinical and laboratory parameters in norrbottnian patients with Gaucher disease type 3. 2015 In: Archivum Immunologiae et Therapiae Experimentalis. - : Springer Science and Business Media LLC. - 0004-069X .- 1661-4917. ; 63:1, s. 65-71 Journal article (peer-reviewed)abstract A viral contamination of the production plant producing imiglucerase (Cerezyme™) resulted in an unpredicted worldwide shortage of global supplies during 2009-2010. The aim of the study was to describe the effects of dose reduction of enzyme replacement therapy (ERT) in adults with Norrbottnian form of Gaucher disease type 3 (N-GD3). There were ten adults with N-GD3 treated with imiglucerase in the county of Norrbotten in June 2009. Analyzed variables included plasma chitotriosidase activity and concentration of CCL18/PARC, whole blood hemoglobin concentration (Hb) and platelet count (PLT), as well as patients' body weight, subjective complaints and health status measured by the EuroQoL-5D questionnaire. The median duration of ERT shortage lasted for 14 months (10-20 months). The median percentage reduction of imiglucerase dose was 36 % (26-59 %). Hb decreased in four patients, PLT decreased in three patients, chitotriosidase increased in three patients (max. +22 % of baseline), and CCL18/PARC increased in six patients (+14 % to +57 %). The body weight was moderately decreased in one patient. No new bone events were noted. Self-assessment of individual patient's health status was stable in all but one patient. Our results suggest that moderate reduction of ERT dosage lasting for relatively short period of time can lead to worsening in biomarkers of adults with N-GD3. However, this worsening is infrequently translated to clinical worsening of patients. It is possible that CCL18/PARC has a higher sensitivity than chitotriosidase in monitoring of ERT dosing in GD3.

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Type of publication: journal article (5)

Type of content: peer-reviewed (3); other academic/artistic (2)

Author/Editor: Myhr-Eriksson, Krist ... (5); Höglund, Martin (4); Lehmann, Sören (3); Antunovic, Petar (3); Möllgård, Lars (2); Uggla, Bertil, 1962- (2); show more...; Wennström, Lovisa (2); Garelius, Hege K. G. (2); Lazarevic, Vladimir (1); Juliusson, Gunnar (1); Abrahamsson, Jonas (1); Hägglund, Hans (1); Juliusson, G (1); Svenningsson, Per (1); Wåhlin, Anders (1); Wahlin, Anders (1); Vestergaard, Hanne (1); Richter, Johan (1); Porkka, Kimmo (1); Hjorth-Hansen, Henri ... (1); Garelius, Hege (1); Derolf, Asa Rangert (1); Mollgard, Lars (1); Uggla, Bertil (1); Lazarevic, V (1); Stentoft, Jesper (1); Mustjoki, Satu (1); Stenke, Leif (1); Dreimane, Arta (1); Lübking, Anna (1); Deneberg, Stefan (1); Derolf, Åsa Rangert (1); Strömberg, Ulla (1); Koskenvesa, Perttu (1); Markevarn, Berit (1); Gedde-Dahl, Tobias (1); Klimkowska, Monika (1); Machaczka, Maciej (1); Gjertsen, Bjorn (1); Gruber, Franz X. (1); Bjerrurn, Ole Weis (1); Wennstrom, Lovisa (1); Swedish AML Group, G ... (1); Swedish Childhood Le ... (1); Rangert-Derolf, Åsa (1); Lazarevic, Vladimir ... (1); Wåhlin, Anders C. E. (1); Juliusson, Gunnar J. (1); Kämpe Björkvall, Cec ... (1); Wieremiejczyk, Joann ... (1); show less...

University: Uppsala University (5); Karolinska Institutet (5); Örebro University (2); Linköping University (2); Umeå University (1); Lund University (1)

Language: English (5)

Research subject (UKÄ/SCB): Medical and Health Sciences (5)

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