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Träfflista för sökning "WFRF:(Näsman P) srt2:(2010-2014)"

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1.	Almquist, T., et al. (author) Lipid-lowering treatment and inflammatory mediators in diabetes and chronic kidney disease 2014 In: European Journal of Clinical Investigation. - : Wiley. - 0014-2972 .- 1365-2362. ; 44:3, s. 276-284 Journal article (peer-reviewed)abstract Background: Inflammation may contribute to the high cardiovascular risk in diabetes mellitus (DM) and chronic kidney disease (CKD). Monocyte chemoattractant protein-1 (MCP-1) facilitates the recruitment of monocytes into atherosclerotic lesions and is involved in diabetic nephropathy. Interferon gamma (IFNγ) is important in atherosclerosis and increases the synthesis of chemokines including MCP-1. Lipid-lowering treatment (LLT) with statins may have anti-inflammatory effects, and ezetimibe cotreatment provides additional cholesterol lowering. Methods: After a placebo run-in period, the effects of simvastatin alone (S) or simvastatin + ezetimibe (S+E) were compared in a randomized, double-blind, cross-over study on inflammatory parameters. Eighteen DM patients with estimated glomerular filtration rate (eGFR) 15-59 mL/min × 1·73 m2 (CKD stages 3-4) (DM-CKD) and 21 DM patients with eGFR > 75 mL/min (DM only) were included. Results: At baseline, monocyte chemoattractant protein 1 (MCP-1) (P = 0·03), IFNγ (P = 0·02), tumour necrosis factor-α (TNFα) (P < 0·01) and soluble vascular adhesion molecule (sVCAM) (P = 0·001) levels were elevated in DM-CKD compared with DM-only patients. LLT with S and S+E reduced MCP-1 levels (P < 0·01 by anova) and IFNγ levels (P < 0·01) in DM-CKD patients but not in DM-only patients. Reductions were most pronounced with the combination treatment. Conclusions: DM patients with CKD stages 3-4 had increased inflammatory activity compared with DM patients with normal GFR. Lipid-lowering treatment decreased the levels of MCP-1 and IFNγ in DM patients with concomitant CKD, which may be beneficial with regard to the progression of both atherosclerosis and diabetic nephropathy.
2.	Holmberg, S, et al. (author) Valu 2010- SVT exit poll survey parliamentary election 2010 (Valu10). 2010 Reports (other academic/artistic)
3.	Holmberg, S, et al. (author) Valu 2014 - EU-parlamenytsvalet. 2014 Conference paper (other academic/artistic)
4.	Holmberg, S, et al. (author) Valu 2014 - SVT exit poll survey parliamentary election 2014. 2014 Reports (other academic/artistic)
5.	Holmberg, S, et al. (author) Valu 2014 - SVT:s vallokalundersökning riksdagsvalet 2014. 2014 Reports (other academic/artistic)
6.	Holmberg, S, et al. (author) Valu - hur väljer det svenska folket? 2014 Conference paper (other academic/artistic)
7.	Liwing, J., et al. (author) Is multiple myeloma a chronic disease? 2012 In: Haematologica. - : Fondazione Ferrata Storti. - 0390-6078 .- 1592-8721. ; 97, s. 345-346 Journal article (other academic/artistic)
8.	Liwing, J, et al. (author) Novel agents are beneficial for real life patients with multiple myeloma not eligible for high dose treatment 2011 Conference paper (other academic/artistic)
9.	Liwing, J, et al. (author) The best response during the 1st line of treatment is strongly correlated to longer time to progression in real life multiple myeloma patients 2011 Conference paper (other academic/artistic)
10.	Munck-Wikland, E, et al. (author) ["Epidemic" increase of tonsillar and base of tongue cancer. Explanation: parallel increase of HPV infections] 2010 In: Lakartidningen. - 0023-7205. ; 107:26-28, s. 1702-4 Journal article (peer-reviewed)

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Type of publication: conference paper (8); reports (6); journal article (6)

Type of content: other academic/artistic (16); peer-reviewed (4)

Author/Editor: Näsman, P (15); Holmberg, S. (9); Uttervall, K (7); Nahi, H (7); Andreasson, J. (6); Aschan, J (6); show more...; Liwing, J (6); Gustafsson, T. (5); GRUBER, A (3); Näsman, Per (2); Wännström, K. (2); Johansson, P. (1); Korhonen, Laura (1); Rydén, L. (1); Paul, E. (1); Malmberg, K (1); Hjemdahl, P (1); Olsson, R (1); Ljungman, P (1); Watz, E. (1); Axdorph-Nygell, U. (1); Ramqvist, T (1); Dalianis, T (1); Kukkonen, Jyrki P. (1); Norhammar, A. (1); Almquist, T (1); Mobarrez, F (1); Jacobson, S. H. (1); Johansson, Lisa (1); Näsman, Per, 1954- (1); Mellbin, L (1); Attner, P (1); Munck-Wikland, E (1); Ungerstedt, J. S. (1); Näsman, A (1); Ritsinger, V. (1); Wahlin, B. E. (1); Hamilton, E (1); Johansson, B.-M. (1); Näsman, Johnny (1); Hammerstedt, L (1); Sjöholm, K (1); Putula, Jaana (1); Turunen, Pauli M (1); Ra, Runar (1); Smardottir, MI (1); show less...

University: Royal Institute of Technology (18); Karolinska Institutet (4); Uppsala University (1); Linköping University (1)

Language: English (14); Swedish (6)

Research subject (UKÄ/SCB): Engineering and Technology (3); Medical and Health Sciences (2)

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