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- Tran, Ngoc Hieu, et al.
(author)
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Genetic profiling of Vietnamese population from large-scale genomic analysis of non-invasive prenatal testing data
- 2020
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In: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 10:1
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Journal article (peer-reviewed)abstract
- The under-representation of several ethnic groups in existing genetic databases and studies have undermined our understanding of the genetic variations and associated traits or diseases in many populations. Cost and technology limitations remain the challenges in performing large-scale genome sequencing projects in many developing countries, including Vietnam. As one of the most rapidly adopted genetic tests, non-invasive prenatal testing (NIPT) data offers an alternative untapped resource for genetic studies. Here we performed a large-scale genomic analysis of 2683 pregnant Vietnamese women using their NIPT data and identified a comprehensive set of 8,054,515 single-nucleotide polymorphisms, among which 8.2% were new to the Vietnamese population. Our study also revealed 24,487 disease-associated genetic variants and their allele frequency distribution, especially 5 pathogenic variants for prevalent genetic disorders in Vietnam. We also observed major discrepancies in the allele frequency distribution of disease-associated genetic variants between the Vietnamese and other populations, thus highlighting a need for genome-wide association studies dedicated to the Vietnamese population. The resulted database of Vietnamese genetic variants, their allele frequency distribution, and their associated diseases presents a valuable resource for future genetic studies.
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2. |
- Dempsey, Tina, et al.
(author)
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Endotracheal intubation performance at a large obstetric hospital delivery room, Hanoi, Vietnam
- 2022
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In: Resuscitation Plus. - : Elsevier. - 2666-5204. ; 12
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Journal article (peer-reviewed)abstract
- Introduction: Intrapartum-related events account for nearly 700,000 neonatal deaths globally yearly. Endotracheal intubation is a cornerstone in preventing many of these deaths, but it is a difficult skill to acquire. Previous studies have described intubation performances in high-income coun-tries, but data from low-and middle-income countries are lacking. We aimed to assess the performance of delivery room intubation in a lower middle -income country.Methods: This prospective observational study was conducted at the Phu San Hanoi Hospital, Vietnam, from September 2020 to January 2021. Video cameras were positioned above the resuscitation tables and data were extracted using adopted software (NeoTapAS). All neonates requiring positive pressure ventilation were included. Our main variables of interest were time to first intubation attempt, first intubation attempt duration, and successful first intubation attempt.Results: 18,107 neonates were born during the five months. Of these, 75 (0.4%) received positive pressure ventilation, and 36 (0.2%) required endotracheal intubation of whom 24 were captured on video. The median time to the first intubation attempt was 252 seconds (range 91-771 sec-onds), the median first attempt duration was 49 seconds (range 10-105 seconds), and the first attempt success rate was 75%.Conclusion: Incidences of positive pressure ventilation and endotracheal intubation were low in comparison to global estimates. Three out of four intubations were successful at the first attempt and the procedural duration was often longer than recommended. Future studies should focus on how to achieve and maintain intubation skills and could include considering alternative devices for airway management at birth.
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3. |
- Dempsey, Tina, et al.
(author)
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Incidence of Intrapartum-Related Events at the Largest Obstetric Hospital in Hanoi, Vietnam : A Retrospective Study
- 2022
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In: Children. - : MDPI AG. - 2227-9067. ; 9:3
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Journal article (peer-reviewed)abstract
- Every year, 2.4 million neonates die during their first month of life and even more suffer permanent injury. The main causes are intrapartum-related events, prematurity, and infection, with sub-Saharan Africa and southern Asia being the worst affected regions. With a focus on intrapartum-related events, we aimed to assess the neonatal demographic characteristics, clinical management, and outcomes among neonates born at the largest obstetric hospital in Hanoi, Vietnam. This was a retrospective cross-sectional study that included all the inborn neonates in November 2019, which was selected as a representative month. A total of 4554 neonates were born during the study period. Of these, 1.0% (n = 44) were stillbirths, 0.15% (n = 7) died in hospital, 0.61% (n = 28) received positive pressure ventilation at birth, and 0.15% (n = 7) were diagnosed with hypoxic ischemic encephalopathy. A total of 581 (13%) neonates were admitted to the neonatal unit, among which the most common diagnoses were prematurity (37%, n = 217) and infection (15%, n = 89). Except for the intrapartum-related events, our findings are consistent with the previously documented data on neonatal morbidity. The intrapartum-related events, however, were surprisingly low in number even in comparison to high-income countries. Research on the current clinical practice at Phu San Hanoi Hospital may bring further clarity to identify the success factors.
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4. |
- Abbafati, Cristiana, et al.
(author)
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- 2020
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Journal article (peer-reviewed)
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5. |
- Luu, Chinh, et al.
(author)
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Framework of Spatial Flood Risk Assessment for a Case Study in Quang Binh Province, Vietnam
- 2020
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In: Sustainability. - Switzerland : MDPI. - 2071-1050. ; 12:7, s. 1-17
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Journal article (peer-reviewed)abstract
- Vietnam has been extensively affected by floods, suffering heavy losses in human life andproperty. While the Vietnamese government has focused on structural measures of flood defence such as levees and early warning systems, the country still lacks flood risk assessment methodologies and frameworks at local and national levels. In response to this gap, this study developed a flood risk assessment framework that uses historical flood mark data and a high- resolution digital elevation model to create an inundation map, then combined this map with exposure and vulnerability data to develop a holistic flood risk assessment map. The case study is the October 2010 flood event in Quang Binh province, which caused 74 deaths, 210 injuries, 188,628 flooded properties, 9019 ha of submerged and damaged agricultural land, and widespread damages to canals, levees, and roads. The final flood risk map showed a total inundation area of 64348 ha, in which 8.3% area of low risk, 16.3% area of medium risk, 12.0% area of high risk, 37.1% area of very high risk, and 26.2% area of extremely high risk. The holistic flood risk assessment map of QuangBinh province is a valuable tool and source for flood preparedness activities at the local scale.
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6. |
- Rydstrom, Helle, et al.
(author)
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THE LGBT MOVEMENT IN VIETNAM1
- 2023
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In: Routledge Handbook of Civil and Uncivil Society in Southeast Asia. - London : Routledge. - 9781000840995 - 9780367422011 ; , s. 223-241
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Book chapter (peer-reviewed)abstract
- This chapter examines mobilisation around sexuality and gender identity in Southeast Asia through an examination of how the lesbian, gay, bisexual, and transgender (LGBT) movement in Vietnam has pursued full recognition and equal rights for all, regardless of sexuality and gender. As the chapter details, the Vietnamese LGBT movement is composed of informal activist groups and networks as well as formally registered, nation-wide associations. The LGBT movement in Vietnam has been galvanised by moral and financial support provided by international non-governmental organisations (NGOs), aid agencies, and representations (e.g. embassies) which include equal rights in their platforms. Over the years, the movement has successfully managed to change public opinion and legislation on sexuality and gender, yet the path to full recognition of LGBT people in Vietnam has been and remains fraught with challenges.
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7. |
- Rydström, Helle, et al.
(author)
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Feminism in Vietnam: Women’s Studies, Gender Research, and Intersections
- 2022
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In: Routledge Handbook of Contemporary Vietnam. - London : Routledge.
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Book chapter (peer-reviewed)abstract
- In this chapter we approach inequalities between women and men in Vietnam through the lens of feminism. We address the manner in which feminism is understood, observing intellectual currents that resonate with global trends in some respects and those reflecting conditions more specific to Vietnam in others. Affinities with global currents, for example, are seen in the ways in which Vietnamese intellectuals have understood the longstanding societal and political goal of reaching ‘equality between men and women’ (nam nữ bình quyền), in which we observe a shift from focusing explicitly on women—in the tradition of women’s studies, to a greater focus on relations between women, men, and other groups—in the tradition of gender studies, and still more recently to an approach that highlights intersectionality, i.e. one focused on intersections of gender and other socially defining parameters such as age, ethnicity, sexuality, masculinity, disability, and class and their implications for individuals, groups, and at a societal level. Whereas the specific meanings of feminism, gender, and intersectionality in Vietnam reflect conditions, experiences, and tensions that are more specific and even to specific regions and identities within it.
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8. |
- Rydström, Helle, et al.
(author)
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The Triple Crisis of Vulnerability : Gendered Violence, Climate Catastrophes and COVID-19 in Asia
- 2021
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Conference paper (peer-reviewed)abstract
- In this presentation we focus on men’s violence against the female population both during and in the wake of climate disasters in the Philippines and Vietnam. We examine the legal framework which has been ratified in the two countries to protect individual’s right to live a life without being abused and; how various types of organizations work to prevent and combat specific kinds of violence in the domestic sphere. In doing so, the presentation highlights the extent to which two rapidly changing Southeast Asian societies have implemented violence preventive legislation and, moreover, how local organizations and agencies maneuver on the plateau of civil society to engage in a perpetual process of demarcating the boundaries of social engagement and responsibility. Furthermore, against the backdrop of the heightened alert of COVID-19 situation, there was an increase in reported incidents of VAWG as observed in almost all countries affected by the pandemic. The pandemic is accentuating and heightening the intersectional pre-existing inequalities that have given rise to specific risks and vulnerabilities.
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