| 1. |
- Blomström-Lundqvist, C, et al.
(author)
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Cardioangiographic findings in patients with arrhythmogenic right ventricular dysplasia
- 1988
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In: British Heart Journal. - 0007-0769. ; 59:5, s. 556-563
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Journal article (peer-reviewed)abstract
- The dimension, contractility, and regional wall motion of the right and left ventricles were scored on the angiograms of 13 patients with arrhythmogenic right ventricular dysplasia. In 10 patients the right ventricle was enlarged, in eight the contractility of the right ventricle was reduced, and in all but one patient there were regional wall motion abnormalities of the right ventricle. The most common abnormality of regional wall motion was mild hypokinesia. There were bulging or dyskinetic areas in seven patients. Regional wall motion abnormalities of the left ventricle were found in five patients, two of whom also had bulging or dyskinetic areas. The reproducibility of right ventricular dimension, contractility, and regional wall motion scores was generally fair but varied unexpectedly both within and between two observers (Kendall's Tau 0.38-0.92). The score values of regional wall motion for some of the segments differed considerably within and between observers. One of the observers consistently gave higher scores than the other. These data suggest that a more objective approach is needed for evaluating angiographic changes in arrhythmogenic right ventricular dysplasia.
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| 2. |
- Olsson, Gustaf, et al.
(author)
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A Model Library for Dynamic Simulation of Activated Sludge Systems
- 1985
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In: Instrumentation and Control of Water and Wastewater Treatment and Transport Systems : Proceedings of the 4th IAWPRC Workshop Held in Houston and Denver, U.S.A., 27 April – 4 May 1985 - Proceedings of the 4th IAWPRC Workshop Held in Houston and Denver, U.S.A., 27 April – 4 May 1985. - 9780080325910 ; , s. 721-728
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Book chapter (peer-reviewed)abstract
- Research has been performed model the dynamics of different kinds of wastewater treatment systems. Plant models are built up from standard modules of subprocesses. Available model knowledge has been packaged into suitable software modules and a library of simulation models has been created. The paper describes this library and the kind of simulations that can be performed.
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| 3. |
- Olsson, Gustaf, et al.
(author)
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Evaluation of Wastewater Treatment Plant Operational Data by a Common Data Base System
- 1985
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In: Instrumentation and Control of Water and Wastewater Treatment and Transport Systems : Proceedings of the 4th IAWPRC Workshop Held in Houston and Denver, U.S.A., 27 April – 4 May 1985 - Proceedings of the 4th IAWPRC Workshop Held in Houston and Denver, U.S.A., 27 April – 4 May 1985. - 9780080325910 ; , s. 443-450
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Book chapter (peer-reviewed)abstract
- The development of a common data base system for wastewater treatment operating data evaluation is discussed. Data records from wastewater treatment plants which have been converted into standard files in a common data base are used as a case study. Advanced programs for data analysis and simulation have been used to evaluate the data in the common data base. The paper discusses software standardization problems and some of the typical results which can be obtained in the analysis of plant operational data.
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| 4. |
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| 5. |
- Olsson, Gustaf, et al.
(author)
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Modelling the Dynamics of Clarifier Behaviour in Activated Sludge Systems : Proceedings of the 4th IAWPRC Workshop Held in Houston and Denver, U.S.A., 27 April – 4 May 1985
- 1985
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In: Instrumentation and Control of Water and Wastewater Treatment and Transport Systems. - 9780080325910 ; , s. 405-412
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Book chapter (peer-reviewed)abstract
- Research was conducted to examine the transient performance of a final settler. Dynamical models of minimal order were derived based on effluent data collected from a pilot scale settler. Parameter values for the models were adjusted until satisfactory fits to the observed data were obtained. Results were compared to select those models with the simplest structures and the ability to predict the major aspects of observed performance. To take into consideration the time-varying character of settling properties, on-line recursive identification was used to update model parameters. Information from such updated models can be incorporated into schemes to control influent pumping and used to warn that those properties are deteriorating.
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| 6. |
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| 7. |
- Auer, R. N., et al.
(author)
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The distribution of hypoglycemic brain damage
- 1984
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In: Acta Neuropathologica. - 0001-6322. ; 64:3, s. 177-191
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Journal article (peer-reviewed)abstract
- Rats were exposed to insulin-induced hypoglycemia resulting in periods of cerebral isoelectricity ranging from 10 to 60 min. After recovery with glucose, they were allowed to wake up and survive for 1 week. Control rats were recovered at the stage of EEG slowing. After sub-serial sectioning, the number and distribution of dying neurons was assessed in each brain region. Acid fuchsin was found to stain moribund neurons a brilliant red. Brains from control rats showed no dying neurons. From 10 to 60 min of cerebral isoelectricity, the number of dying neurons per brain correlated positively with the number of minutes of cerebral isoelectricity up to the maximum examined period of 60 min. Neuronal necrosis was found in the major brain regions vulnerable to several different insults. However, within each region the damage was not distributed as observed in ischemia. A superficial to deep gradient in the density of neuronal necrosis was seen in the cerebral cortex. More severe damage revealed a gradient in relation to the subjacent white matter as well. The caudatoputamen was involved more heavily near the white matter, and in more severely affected animals near the angle of the lateral ventricle. The hippocampus showed dense neuronal necrosis at the crest of the dentate gyrus and a gradient of increasing selective neuronal necrosis medially in CA1. The CA3 zone, while relatively resistant, showed neuronal necrosis in relation to the lateral ventricle in animals with hydrocephalus. Sharp demarcations between normal and damaged neuropil were found in the hippocampus. The periventricular amygdaloid nuclei showed damage closest to the lateral ventricles. The cerebellum was affected first near the foramina of Luschka, with damage occurring over the hemispheres in more severely affected animals. Purkinje cells were affected first, but basket cells were damaged as well. Rare necrotic neurons were seen in brain stem nuclei. The spinal cord showed necrosis of neurons in all areas of the gray matter. Infarction was not seen in this study. The possibility is discussed that a neurotoxic substance borne in the tissue fluid and cerebrospinal fluid (CSF) contributes to the pathogenesis of neuronal necrosis in hypoglycemic brain damage.
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| 8. |
- Auer, R., et al.
(author)
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The dentate gyrus in hypoglycemia : Pathology implicating excititoxin-mediated neuronal necrosis
- 1985
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In: Acta Neuropathologica. - 0001-6322. ; 67:3-4, s. 279-288
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Journal article (peer-reviewed)abstract
- A detailed light- and electron-microscopic study of the damage to the rat dentate gyrus in hypoglycemia was undertaken, in view of the previously advanced hypothesis that hypoglycemic nerve cell injury is mediated by a released neurotoxin. The distribution of neuronal necrosis showed a relationship to the subarachnoid cisterns. Electron microscopy of the dentate granule cells and their apical dendrites revealed dendrosomal, axon-sparing neuronal pathology. Dentate granule cells were affected first in the dendrites in the outer layer of the stratum moleculare, sparing axons of passage and terminal boutons. Subsequently, the neuronal perikarya were affected, and Wallerian degeneration of axons followed. Cell membrane abnormalities preceded the appearance of mitochondrial flocculent densities and degradation of the cytoskeleton, and are suggested to be early lethal changes. The observed early dendrotoxic changes, and the dendrosomal, axon-sparing nature of the lesion implicate an excitotoxin-mediated neuronal necrosis in hypoglycemia.
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| 9. |
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| 10. |
- Berggren, H, et al.
(author)
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Myocardial Protective Effect of Maintained Beta-Blockade in Aorto-Coronary Bypass Surgery
- 1983
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In: Scandinavian Cardiovascular Journal. - : Informa Healthcare. - 1401-7431 .- 1651-2006. ; 17:1, s. 29-32
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Journal article (peer-reviewed)abstract
- Twenty-nine patients were randomly allocated to two groups before undergoing aorto-coronary bypass surgery. In one group the beta-blocking medication was withdrawn three days preoperatively, and in the other group it was maintained. The patients in the latter group were additionally given 100 mg metoprolol per os two hours before surgery. The degree of myocardial injury, as judged from cumulated activity of S-CK B, was less when the beta-blockade was maintained.
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