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- Koide, T., et al.
(author)
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Circulating catecholamines modulate ischemic brain damage
- 1986
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In: Journal of Cerebral Blood Flow and Metabolism. - : SAGE Publications. - 0271-678X .- 1559-7016. ; 6:5, s. 559-565
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Journal article (peer-reviewed)abstract
- In search of factors influencing the outcome of an ischemic insult, we induced 10 min of forebrain ischemia in rats and assessed neuronal necrosis by quantitative histopathology after 1 week of recovery. Procedures for inducing ischemia included bilateral carotid artery clamping and reduction of blood pressure to 40–50 mm Hg by bleeding. To facilitate rapid lowering of blood pressure, a ganglionic blocker, trimethaphan (TMP), was administered at the onset of ischemia. Omission of the ganglionic blocker proved to markedly ameliorate neuronal damage. Similarly favorable effects were obtained when a mixture of adrenaline and noradrenaline (1 μg kg−1 min−1 each) was infused during the early recirculation period in animals previously given TMP. Infusion of noradrenaline alone also ameliorated the damage, though the efficacy was somewhat less. The results suggest that catecholamines, released as a response to stress, ameliorate ischemic brain damage.
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- Thorsson, Pontus, 1974
(author)
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A parametric method to synthesize wind turbine sounds
- 2019
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In: Proceedings of the International Congress on Acoustics. - 2226-7808 .- 2415-1599. ; 2019-September, s. 1675-1682
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Conference paper (peer-reviewed)abstract
- The annoyance to wind turbine sound is today well known. There is no doubt that increased sound pressure level causes in general an increased annoyance. However, when it comes to additional descriptors of the wind turbine sound, such as e g equivalent frequency spectrum or amplitude modulation, there is no consensus on what parameters that are most important. In the research project Wind Turbine Noise Effects on Sleep (WiTNES) there was a need for 8 hour long sound signals from wind turbines that were completely free of extraneous sounds. Recordings from reality are difficult to maintain free from disturbances. Instead a parametric synthesis method was developed that is capable of creating wind turbine sounds of arbitrary length. The sounds can be designed in terms of equivalent frequency spectrum, what frequency bands that have amplitude modulation as well as frequency dependent amplitude modulation strength and variation. Recordings of wind turbine sounds at immission distances from different wind turbine types were used to find relevant values for the parameters. This paper describes the synthesis method and some examples of input parameters.
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