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| 3. |
- Varli, IH, et al.
(author)
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The Stockholm classification of stillbirth
- 2008
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In: Acta obstetricia et gynecologica Scandinavica. - : Wiley. - 1600-0412 .- 0001-6349. ; 87:11, s. 1202-1212
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Journal article (peer-reviewed)
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- Emmoth, Birger, et al.
(author)
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In-situ measurements of carbon and deuterium deposition using the fast reciprocating probe in TEXTOR
- 2009
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In: Journal of Nuclear Materials. - : Elsevier BV. - 0022-3115 .- 1873-4820. ; 390-91, s. 179-182
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Journal article (peer-reviewed)abstract
- Silicon samples were exposed in the scrape-off layer of the TEXTOR plasma using a fast reciprocating probe, with the aim of studying carbon deposition and deuterium retention during Dynamic Ergodic Divertor (DED) operation. Separate samples were exposed for 300 ms at the flat-top phase of neutral beam heated discharges. The exposure conditions were varied on a shot-to-shot basis by external magnetic perturbations generated by the DED in the m/n = 3/1, DC regime, base configuration. Nuclear Reaction Analysis (NRA) was used to characterise collector sample surfaces after their exposure. Enhanced concentrations of both carbon and deuterium (C 3-10 x 10(16) at./cm(2), D 8-60 x 10(15) at./cm(2)) were found. The D/C ratio was less than unity which indicates that most of the carbon and deuterium were co-deposited. Carbon e-folding lengths of about 2 cm were found on both toroidal sides of the probe independent of DED perturbations.
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| 7. |
- Friberg, L. E., et al.
(author)
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An agonist-antagonist interaction model for prolactin release following risperidone and paliperidone treatment
- 2009
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In: Clinical Pharmacology and Therapeutics. - : Springer Science and Business Media LLC. - 0009-9236 .- 1532-6535. ; 85:4, s. 409-417
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Journal article (peer-reviewed)abstract
- A mechanistic pharmacokinetic/pharmacodynamic model is presented, characterizing the time course of prolactin in healthy as well as schizophrenic subjects following the administration of various doses and formulations of the antipsychotic drugs risperidone and paliperidone. Prolactin concentrations from nine studies (1,462 subjects) were analyzed in NONMEM. A competitive agonist-antagonist interaction model described the competition between these drugs and dopamine for the D(2) receptors that regulate prolactin release. Tolerance development was explained by a feedback loop with prolactin stimulating dopamine release, whereas models wherein tolerance is described in terms of depletion of a prolactin pool did not explain the data well. The diurnal prolactin rhythm was described by a two-period cosine function. Baseline prolactin was health-status dependent and higher in women than in men, although the drug-induced release was less than proportional to baseline. This quantitative mechanism-based model is the first to describe prolactin release in patients, and it confirms that paliperidone and risperidone have similar potencies for prolactin release.
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| 9. |
- Kreter, A., et al.
(author)
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Fuel retention in carbon materials under ITER-relevant mixed species plasma conditions
- 2009
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In: Physica scripta. T. - : Institute of Physics Publishing (IOPP). - 0281-1847 .- 0031-8949 .- 1402-4896. ; T138, s. 014012-
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Journal article (peer-reviewed)abstract
- Samples of CFC NB41 and fine-grain graphite ATJ have been exposed to PISCES plasmas containing (i) pure deuterium, (ii) deuterium and beryllium, (iii) deuterium, beryllium and helium, and (iv) deuterium, beryllium and argon. Thermal desorption spectrometry (TDS) and nuclear reaction analysis (NRA) have been used to measure the amount and distribution of retained deuterium in the samples. For the case of pure deuterium plasma, parametric studies of deuterium retention in NB41 have been done with variations of the incident deuterium fluence (Phi = 1 x 10(25)-5 x 10(26) m(-2)), ion energy (E-i = 20-120 eV) and sample surface temperature (T-s = 370-820 K). It has been found, that for T-s = 470K the retention scales as Phi(0.35). For T-s = 820K the retention saturates at a level of similar to 10(21) Dm(-2). The retention increases with E-i and drops with higher T-s. At T-s = 720 K, the beryllium seeding results in a building of a protective beryllium carbide layer, which appears to prevent the in-bulk diffusion of deuterium, thus reducing the retention. Admixture of Ar and, in the case of low E-i, He leads to a significant reduction of the retention.
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