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Träfflista för sökning "WFRF:(Pierard D.) srt2:(2010-2014)"

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1.	Everard, A., et al. (author) Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status 2014 In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 5:5648 Journal article (peer-reviewed)abstract Obesity is associated with a cluster of metabolic disorders, low-grade inflammation and altered gut microbiota. Whether host metabolism is controlled by intestinal innate immune system and the gut microbiota is unknown. Here we report that inducible intestinal epithelial cell-specific deletion of MyD88 partially protects against diet-induced obesity, diabetes and inflammation. This is associated with increased energy expenditure, an improved glucose homeostasis, reduced hepatic steatosis, fat mass and inflammation. Protection is transferred following gut microbiota transplantation to germ-free recipients. We also demonstrate that intestinal epithelial MyD88 deletion increases anti-inflammatory endocannabinoids, restores antimicrobial peptides production and increases intestinal regulatory T cells during diet-induced obesity. Targeting MyD88 after the onset of obesity reduces fat mass and inflammation. Our work thus identifies intestinal epithelial MyD88 as a sensor changing host metabolism according to the nutritional status and we show that targeting intestinal epithelial MyD88 constitutes a putative therapeutic target for obesity and related disorders.
2.	Kristensen, SD, et al. (author) 2014 ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and management: The Joint Task Force on non-cardiac surgery: cardiovascular assessment and management of the European Society of Cardiology (ESC) and the European Society of Anaesthesiology (ESA) 2014 In: European journal of anaesthesiology. - 1365-2346. ; 31:10, s. 517-573 Journal article (peer-reviewed)
3.	Kristensen, SD, et al. (author) 2014 ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and management: The Joint Task Force on non-cardiac surgery: cardiovascular assessment and management of the European Society of Cardiology (ESC) and the European Society of Anaesthesiology (ESA) 2014 In: European heart journal. - : Oxford University Press (OUP). - 1522-9645 .- 0195-668X. ; 35:35, s. 2383-2431 Journal article (peer-reviewed)
4.	Poldermans, D, et al. (author) Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery: the Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Non-cardiac Surgery of the European Society of Cardiology (ESC) and endorsed by the European Society of Anaesthesiology (ESA) 2010 In: European journal of anaesthesiology. - 1365-2346. ; 27:2, s. 92-137 Journal article (peer-reviewed)
5.	Vahanian, A., et al. (author) Guidelines on the management of valvular heart disease (version 2012): The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) 2012 In: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. - : Oxford University Press (OUP). - 1873-734X. ; 42:4 Journal article (other academic/artistic)
6.	Vahanian, A., et al. (author) Guidelines on the management of valvular heart disease (version 2012): The Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) 2012 In: European heart journal. - : Oxford University Press (OUP). - 1522-9645 .- 0195-668X. ; 33:19, s. 2451-96 Journal article (peer-reviewed)

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Result 1-6 of 6

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Type of publication: journal article (6)

Type of content: peer-reviewed (5); other academic/artistic (1)

Author/Editor: Iung, B (5); Pierard, L (5); Price, S (4); Knuuti, J. (4); Funck-Brentano, C. (4); De Hert, S (3); show more...; Gorenek, B (3); Schuler, G. (2); Evangelista, A. (2); Filippatos, G (2); Piazza, N (2); Ford, I. (2); Swedberg, Karl, 1944 (2); Lip, G. Y. (2); Roffi, M (2); Tendera, M (2); Pocock, S. (2); Walther, T. (2); McDonagh, T (2); Baron-Esquivias, G (2); Sechtem, U (2); Andreotti, F (2); Huber, K (2); Reiner, Z (2); Hoeft, A (2); Luescher, TF (2); Vahanian, A (2); Kirchhof, P. (2); Saraste, A. (2); Schwitter, J. (2); Baumgartner, H (2); Falk, V (2); De Bonis, M (2); Lancellotti, P (2); Rosenhek, R (2); Windecker, S (2); Dean, V (2); Bunc, M (2); Habib, G (2); Bax, J J (2); Kolh, P (2); Torbicki, A (2); Claeys, M. J. (2); Anker, S (2); Sirnes, PA (2); Stepinska, J (2); Fagard, R. (2); Ceconi, C (2); Hoes, A (2); Pepper, J. (2); show less...

University: University of Gothenburg (3); Karolinska Institutet (3)

Language: English (6)

Research subject (UKÄ/SCB): Medical and Health Sciences (3)

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