| 1. |
- Bondesson, Susanne M., et al.
(author)
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Hospital utilization and costs for spinal cord stimulation compared with enhanced external counterpulsation for refractory angina pectoris
- 2013
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In: Journal of Evaluation In Clinical Practice. - : Wiley-Blackwell. - 1356-1294 .- 1365-2753. ; 19:1, s. 139-147
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Journal article (peer-reviewed)abstract
- Rationale, aims and objectives The aim of this study was to compare acute hospital utilization and costs for patients with refractory angina pectoris undergoing spinal cord stimulation (SCS) versus enhanced external counterpulsation (EECP). Method Seventy-three persons were included in this register study. The acute hospital utilization and costs for SCS and EECP were followed over a period from 12 months before treatment to 24 months after treatment using Patient Administrative Support in Skåne for publicly organized care. Results SCS was significantly more expensive than EECP (P < 0.001). Both SCS and EECP entailed fewer days of hospitalization for coronary artery disease in the 12-month follow-up compared with the 12 months preceding treatment. Patients treated with EECP showed an association between reduced hospital admissions and an improved Canadian Cardiovascular Society classification class compared with 1 year before treatment. A significant reduction in cost was seen in both the SCS group (P = 0.018 and P = 0.001, respectively) and the EECP group (P = 0.002 and P = 0.045, respectively) during 12 and 24 months of follow-up compared with before treatment. There were no significant differences between the groups for hospitalization days or admissions, including costs, at the different follow-ups. Conclusions Cost-effective treatment modalities such as SCS and EECP are valuable additions to medical and revascularization therapy in patients with refractory angina pectoris. Pre-existing conditions and the patient's preferences should be taken in consideration when clinicians choose between treatments for this group of patients.
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| 2. |
- Bonaglia, Stefano, et al.
(author)
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Effect of reoxygenation and Marenzelleria spp. bioturbation on Baltic Sea sediment metabolism
- 2013
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In: Marine Ecology Progress Series. - : Inter Research. - 0171-8630 .- 1616-1599. ; 482, s. 43-55
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Journal article (peer-reviewed)abstract
- Nutrient reduction and the improvement of bottom water oxygen concentrations are thought to be key factors in the recovery of eutrophic aquatic ecosystems. The effects of reoxygenation and bioturbation of natural hypoxic sediments in the Baltic Sea were studied using a mesocosm experiment. Anoxic sediment box cores were collected from 100 m depth in Kanholmsfjärden (Stockholm Archipelago) and maintained in flow-through mesocosms with 3 treatments: (1) hypoxic: supplied with hypoxic water; (2) normoxic: supplied with oxic water; and (3) Marenzelleria: supplied with oxic water and the polychaete Marenzelleria spp. (2000 ind. m–2). After a 7 wk long conditioning period, net fluxes of dissolved O2, CH4, Fe2+, Mn2+, NH4+, NO2-, NO3-, PO43- and H4SiO4, and rates of nitrate ammonification (DNRA), denitrification and anammox were determined. Phosphate was taken up by the sediment in all treatments, and the uptake was highest in the normoxic treatment with Marenzelleria. Normoxic conditions stimulated the denitrification rate by a factor of 5. Denitrification efficiency was highest under normoxia (50%), intermediate in bioturbated sediments (16%), and very low in hypoxic sediments (4%). The shift from hypoxic to normoxic conditions resulted in a significantly higher retention of NH4+, H4SiO4 and Mn2+ in the sediment, but the bioturbation by Marenzelleria reversed this effect. Results from our study suggest that bioturbation by Marenzelleria stimulates the exchange of solutes between sediment and bottom water through irrigation and enhances bacterial sulfate reduction in the burrow walls. The latter may have a toxic effect on nitrifying bacteria, which, in turn, suppresses denitrification rates.
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| 3. |
- Bondesson, Susanne, et al.
(author)
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Effects on blood pressure in patients with refractory angina pectoris after enhanced external counterpulsation
- 2010
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In: Blood Pressure. - : Informa UK Limited. - 0803-7051 .- 1651-1999. ; 19:5, s. 287-294
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Journal article (peer-reviewed)abstract
- Objective. Enhanced external counterpulsation (EECP) is a non-invasive technique that has been shown to reduce the frequency and severity of angina pectoris. Little is known how EECP affects the blood pressure. Methods. 153 patients with refractory angina were treated with either EECP or retained on their pharmacological treatment (reference group). Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP) and heart rate were measured pre- and post-treatment and at 12 months follow-up. Results. EECP treatment altered the blood pressure in patients with refractory angina pectoris. A decrease in the blood pressure was more common in the EECP group compared with the reference group. In the reference group, an increase in the blood pressure was more common. A correlation between a decrease in blood pressure after EECP treatment and a higher baseline MAP, SBP and DBP was seen. No such correlation was seen in the reference group. The blood pressure response did not persist at 12 months follow-up. Conclusion. EECP treatment affects the blood pressure in patients with refractory angina pectoris. The decreased blood pressure may be a result of an improved exercise capacity, an improved endothelial function and vasoreactivity in general.
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| 4. |
- Bondesson, Susanne, et al.
(author)
-
Hospital utilization and costs for spinal cord stimulation compared with enhanced external counterpulsation for refractory angina pectoris
- 2013
-
In: Journal of Evaluation in Clinical Practice. - : Wiley-Blackwell Publishing Ltd. - 1356-1294 .- 1365-2753. ; 19:1, s. 139-147
-
Journal article (peer-reviewed)abstract
- Rationale, aims and objectives The aim of this study was to compare acute hospital utilization and costs for patients with refractory angina pectoris undergoing spinal cord stimulation (SCS) versus enhanced external counterpulsation (EECP). Method Seventy-three persons were included in this register study. The acute hospital utilization and costs for SCS and EECP were followed over a period from 12 months before treatment to 24 months after treatment using Patient Administrative Support in Skåne for publicly organized care. Results SCS was significantly more expensive than EECP (P < 0.001). Both SCS and EECP entailed fewer days of hospitalization for coronary artery disease in the 12-month follow-up compared with the 12 months preceding treatment. Patients treated with EECP showed an association between reduced hospital admissions and an improved Canadian Cardiovascular Society classification class compared with 1 year before treatment. A significant reduction in cost was seen in both the SCS group (P = 0.018 and P = 0.001, respectively) and the EECP group (P = 0.002 and P = 0.045, respectively) during 12 and 24 months of follow-up compared with before treatment. There were no significant differences between the groups for hospitalization days or admissions, including costs, at the different follow-ups. Conclusions Cost-effective treatment modalities such as SCS and EECP are valuable additions to medical and revascularization therapy in patients with refractory angina pectoris. Pre-existing conditions and the patient's preferences should be taken in consideration when clinicians choose between treatments for this group of patients.
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| 5. |
- Brandtler, Johan, et al.
(author)
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Framväxten av obestämd artikel i svenska
- 2010
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In: Svensson och Svenskan - Med sinnen känsliga för språk. - 9789163356841 ; , s. 24-36
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Book chapter (other academic/artistic)
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| 6. |
- Liberg, Benny, et al.
(author)
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Motor imagery in bipolar depression with slowed movement.
- 2013
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In: The Journal of nervous and mental disease. - 1539-736X. ; 201:10, s. 885-93
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Journal article (peer-reviewed)abstract
- We hypothesized that motor retardation in bipolar depression is mediated by disruption of the pre-executive stages of motor production. We used functional magnetic resonance imaging to investigate neural activity during motor imagery and motor execution to elucidate whether brain regions that mediate planning, preparation, and control of movement are activated differently in subjects with bipolar depression (n = 9) compared with healthy controls (n = 12). We found significant between-group differences. During motor imagery, the patients activated the posterior medial parietal cortex, the posterior cingulate cortex, the premotor cortex, the prefrontal cortex, and the frontal poles more than the controls did. Activation in the brain areas involved in motor selection, planning, and preparation was altered. In addition, limbic and prefrontal regions associated with self-reference and the default mode network were altered during motor imagery in bipolar depression with motor retardation.
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| 7. |
- Lonne-Rahm, Sol-Britt, et al.
(author)
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Adult atopic dermatitis patients and physical exercise : a Swedish questionnaire study.
- 2014
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In: Acta Dermato-Venereologica. - : Medical Journals Sweden AB. - 0001-5555 .- 1651-2057. ; 94:2, s. 185-7
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Journal article (peer-reviewed)abstract
- Physical activity promotes health and prevents disease. When patients with atopic dermatitis (AD) undertake exercise, the itch often gets worse due to sweating, and this may reduce their engagement in physical exercise. The aim of this study was to determine the level of physical exercise in patients with AD compared with a control group from a normal population. Our hypothesis was that patients with AD have a lower level of physical exercise due to their skin disease. A total of 110 patients with AD and 196 subjects from a normal population, age range 20-34 years, answered a questionnaire. Eleven patients with AD underwent an in-depth interview. The patients with AD had the same level of physical exercise and attitude to physical exercise as the normal population. Therefore, our hypothesis could not be confirmed. In conclusion, the skin symptoms of AD do not appear to be an obstacle to moderate physical exercise.
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| 8. |
- Papush, Liana
(author)
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Silicon cycling in the Baltic Sea : Trends and budget of dissolved silica
- 2011
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Doctoral thesis (other academic/artistic)abstract
- The dissolved silicon (DSi) has a crucial role for growth of a large group of primary producers – diatoms and, hence, impact on functioning of the aquatic food web. This thesis contributes to an increased understanding of the modifications of the DSi cycling in the Baltic Sea. The results provide new information about spatial and temporal changes in DSi concentrations and nutrient ratios for the period 1970-2001 as well as during the 20th century.For the period 1970-2001, the declining DSi trends were found at the majority of monitoring stations all over the Baltic Sea. This decrease is assumed to be mainly due to the ongoing eutrophication. It is supported by the increasing trends of inorganic nitrogen and phosphorus. The trends have implications for the nutrient ratios, DSi:DIN and DSi:DIP, which are important indicators of the state of an ecosystem. The long-term retrospective DSi budget has shown that the DSi concentrations before major hydrological alterations and eutrophication were about twice the present ones. This decrease is related to both eutrophication and anthropogenic perturbations in the catchment.The occurrence of DSi concentrations close to the potentially limiting levels has been also analysed. While DSi concentrations are still high in the northern regions of the Baltic, other areas may be at risk of developing Si limitation if the decrease in DSi concentrations persists. The results depict the Baltic Sea journey from being water body with DSi levels sufficient to support diatom production to one that may experience Si limitation and its adverse ecological consequences.
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| 9. |
- Shakeri Yekta, Sepehr, et al.
(author)
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A model study of the effects of sulfide-oxidizing bacteria (Beggiatoa spp.) on phosphorus retention processes in hypoxic sediments : implications for phosphorus management in the Baltic Sea
- 2011
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In: Boreal environment research. - : Boreal Environment Research Publishing Board. - 1239-6095 .- 1797-2469. ; 16:3, s. 167-184
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Journal article (peer-reviewed)abstract
- Ongoing eutrophication increases phosphorus storage in surficial sediments of the Baltic Sea which can then be released during hypoxic/anoxic events. Such sediments are suitable habitats for sulfide-oxidizing bacteria, Beggiatoa spp. The objective of this paper is to investigate the effects of these bacteria on the P retention processes in hypoxic sediments using a diagenetic model. This model simulates interactions of the processes controlling P mobility in the sediments with redox reactions from the Beggiatoa metabolism. Modeling results demonstrate that P retention capability is limited when dissolved iron is mineralized as iron sulfides in the sediments. In this regard, sulfide consumption by Beggiatoa spp. potentially decreases the rate of iron sulfide formation and consequently increases the P retention capability in local-scale sediment.
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| 10. |
- Stigebrandt, Anders, 1942, et al.
(author)
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A new Phosphorus Paradigm for the Baltic Proper
- 2014
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In: Ambio. - : Springer Science and Business Media LLC. - 0044-7447 .- 1654-7209. ; 43:5, s. 634-643
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Journal article (peer-reviewed)abstract
- The external phosphorus (P) loading has been halved, but the P content in the water column and the area of anoxic bottoms in Baltic proper has increased during the last 30 years. This can be explained by a temporary internal source of dissolved inorganic phosphorus (DIP) that is turned on when the water above the bottom sediment becomes anoxic. A load-response model, explaining the evolution from 1980 to 2005, suggests that the average specific DIP flux from anoxic bottoms in the Baltic proper is about 2.3 g P m-2 year-1. This is commensurable with fluxes estimated in situ from anoxic bottoms in the open Baltic proper and from hydrographic data in the deep part of Bornholm Basin. Oxygenation of anoxic bottoms, natural or manmade, may quickly turn off the internal P source from anoxic bottoms. This new P-paradigm should have far-reaching implications for abatement of eutrophication in the Baltic proper.
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