| 1. |
- Poley, L., et al.
(author)
-
The ABC130 barrel module prototyping programme for the ATLAS strip tracker
- 2020
-
In: Journal of Instrumentation. - : IOP PUBLISHING LTD. - 1748-0221 .- 1748-0221. ; 15:9
-
Journal article (peer-reviewed)abstract
- For the Phase-II Upgrade of the ATLAS Detector [1], its Inner Detector, consisting of silicon pixel, silicon strip and transition radiation sub-detectors, will be replaced with an all new 100% silicon tracker, composed of a pixel tracker at inner radii and a strip tracker at outer radii. The future ATLAS strip tracker will include 11,000 silicon sensor modules in the central region (barrel) and 7,000 modules in the forward region (end-caps), which are foreseen to be constructed over a period of 3.5 years. The construction of each module consists of a series of assembly and quality control steps, which were engineered to be identical for all production sites. In order to develop the tooling and procedures for assembly and testing of these modules, two series of major prototyping programs were conducted: an early program using readout chips designed using a 250 nm fabrication process (ABCN-250) [2, 3] and a subsequent program using a follow-up chip set made using 130 nm processing (ABC130 and HCC130 chips). This second generation of readout chips was used for an extensive prototyping program that produced around 100 barrel-type modules and contributed significantly to the development of the final module layout. This paper gives an overview of the components used in ABC130 barrel modules, their assembly procedure and findings resulting from their tests.
|
|
| 2. |
|
|
| 3. |
|
|
| 4. |
- Da Silva Santos, J. M., et al.
(author)
-
Subarcsecond Imaging of a Solar Active Region Filament With ALMA and IRIS
- 2022
-
In: Frontiers in Astronomy and Space Sciences. - : Frontiers Media SA. - 2296-987X. ; 9
-
Journal article (peer-reviewed)abstract
- Quiescent filaments appear as absorption features on the solar disk when observed in chromospheric lines and at continuum wavelengths in the millimeter (mm) range. Active region (AR) filaments are their small-scale, low-altitude analogues, but they could not be resolved in previous mm observations. This spectral diagnostic can provide insight into the details of the formation and physical properties of their fine threads, which are still not fully understood. Here, we shed light on the thermal structure of an AR filament using high-resolution brightness temperature (Tb) maps taken with ALMA Band 6 complemented by simultaneous IRIS near-UV spectra, Hinode/SOT photospheric magnetograms, and SDO/AIA extreme-UV images. Some of the dark threads visible in the AIA 304 Å passband and in the core of Mg ii resonance lines have dark (Tb << 5,000 K) counterparts in the 1.25 mm maps, but their visibility significantly varies across the filament spine and in time. These opacity changes are possibly related to variations in temperature and electron density in filament fine structures. The coolest Tb values (<< 5,000 K) coincide with regions of low integrated intensity in the Mg ii h and k lines. ALMA Band 3 maps taken after the Band 6 ones do not clearly show the filament structure, contrary to the expectation that the contrast should increase at longer wavelengths based on previous observations of quiescent filaments. The ALMA maps are not consistent with isothermal conditions, but the temporal evolution of the filament may partly account for this.
|
|
| 5. |
- Ludwig, Sebastian, et al.
(author)
-
Transcatheter Mitral Valve Replacement versus Medical Therapy for Secondary Mitral Regurgitation: A Propensity Score-Matched Comparison.
- 2023
-
In: Circulation. Cardiovascular interventions. - 1941-7632. ; 16:6
-
Journal article (peer-reviewed)abstract
- Background: Transcatheter mitral valve replacement (TMVR) is an emerging therapeutic alternative for patients with secondary mitral regurgitation (MR). Outcomes of TMVR versus guideline-directed medical therapy (GDMT) have not been investigated for this population. This study aimed to compare clinical outcomes of patients with secondary MR undergoing TMVR versus GDMT alone. Methods: The CHOICE-MI registry included patients with MR undergoing TMVR using dedicated devices. Patients with MR etiologies other than secondary MR were excluded. Patients treated with GDMT alone were derived from the control arm of the COAPT trial. We compared outcomes between the TMVR and GDMT groups, using propensity score (PS)-matching to adjust for baseline differences. Results: After PS-matching, 97 patient pairs undergoing TMVR (72.9±8.7 years, 60.8% male, transapical access 91.8%) versus GDMT (73.1±11.0 years, 59.8% male) were compared. At 1 and 2 years, residual MR was ≤1+ in all patients of the TMVR group compared to 6.9% and 7.7%, respectively, in those receiving GDMT alone (both p<0.001). The 2-year rate of HF hospitalization was significantly lower in the TMVR group (32.8% vs. 54.4%, HR 0.59, 95% CI 0.35-0.99; p=0.04). Among survivors, a higher proportion of patients were in NYHA functional class I or II in the TMVR group at 1 year (78.2% vs. 59.7%, p=0.03) and at 2 years (77.8% vs. 53.2%, p=0.09). Two-year mortality was similar in the two groups (TMVR vs. GDMT, 36.8% vs. 40.8%, HR 1.01, 95% CI 0.62-1.64; p=0.98). Conclusions: In this observational comparison, over 2-year follow-up, TMVR using mostly transapical devices in patients with secondary MR was associated with significant reduction of MR, symptomatic improvement, less frequent hospitalizations for HF and similar mortality compared with GDMT.
|
|
| 6. |
|
|
