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Search: WFRF:(Reisner Walter) > (2007)

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  • Reisner, Walter, et al. (author)
  • Nanoconfinement-enhanced conformational response of single DNA molecules to changes in ionic environment
  • 2007
  • In: Physical Review Letters. - 1079-7114. ; 99:5
  • Journal article (peer-reviewed)abstract
    • We show that the ionic environment plays a critical role in determining the configurational properties of DNA confined in silica nanochannels. The extension of DNA in the nanochannels increases as the ionic strength is reduced, almost tripling over two decades in ionic strength for channels around 100x100 nm in dimension. Surprisingly, we find that the variation of the persistence length alone with ionic strength is not enough to explain our results. The effect is due mainly to increasing self-avoidance created by the reduced screening of electrostatic interactions at low ionic strength. To quantify the increase in self-avoidance, we introduce a new parameter into the de Gennes theory: an effective DNA width that gives the increase in the excluded volume due to electrostatic repulsion.
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  • Result 1-3 of 3
Type of publication
conference paper (2)
journal article (1)
Type of content
peer-reviewed (3)
Author/Editor
Tegenfeldt, Jonas (3)
Beech, Jason (3)
Kristensen, Anders (3)
Flyvbjerg, Henrik (3)
Reisner, Walter (3)
Larsen, Niels (2)
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Larsen, Niels B. (1)
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University
Lund University (3)
Language
English (3)
Research subject (UKÄ/SCB)
Natural sciences (3)
Year
2007 (3)Undo refine

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