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1.	Kamnaing, P, et al. (author) Trypanocidal diarylheptanoids from Aframomum letestuianum K. Schum (Zingiberaceae). 2003 In: Journal of Natural Products. - : American Chemical Society (ACS). - 0163-3864 .- 1520-6025. ; 66:3, s. 364-367 Journal article (peer-reviewed)abstract Three new diarylheptanoids, (4Z,6E)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-4,6-dien-3-one, letestuianin A (1), (4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-4,6-dien-3-one, letestuianin B (2), and 1,7-bis(4-hydroxyphenyl)heptan-3,5-dione, letestuianin C (3), as well as the known (4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-4,6-dien-3-one (5) were isolated from Aframomum letestuianum. The known flavonoids 3-acetoxy-5,7,4'-trihydroxyflavanone, 3-acetoxy-7-methoxy-5,4'-dihydroxyflavanone, 7-methoxy-3,5,4'-trihydroxyflavone, and 3,3',4',5,7-pentahydroxyflavan were also obtained from this plant. Their structures were determined using a combination of 1D and 2D NMR techniques. The four diarylheptanoids were tested for growth inhibitory activity in vitro versus bloodstream forms of African trypanosomes. IC50 values in the range of 1-3 g/mL were found for compounds 3 and 5.
2.	Gafvels, M, et al. (author) Targeted deletion of the intronless sterol 12 alpha hydroxylase (CYP8B1) gene in mice leads to loss of cholic acid production but upregulated bile acid synthesis. 2001 In: HEPATOLOGY. - 0270-9139. ; 34:4, s. 353A-353A Conference paper (other academic/artistic)
3.	Li-Hawkins, J, et al. (author) Cholic acid mediates negative feedback regulation of bile acid synthesis in mice 2002 In: The Journal of clinical investigation. - 0021-9738. ; 110:8, s. 1191-1200 Journal article (peer-reviewed)
4.	Tefs, K, et al. (author) Characterization of plasminogen variants in healthy subjects and plasminogen mutants in patients with inherited plasminogen deficiency by isoelectric focusing gel electrophoresis 2004 In: Thrombosis and haemostasis. - 0340-6245. ; 92:2, s. 352-357 Journal article (peer-reviewed)
5.	Alberti, S, et al. (author) Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice 2001 In: The Journal of clinical investigation. - 0021-9738. ; 107:5, s. 565-573 Journal article (peer-reviewed)
6.	Steffensen, KR, et al. (author) Gene expression profiling in adipose tissue indicates different transcriptional mechanisms of liver X receptors alpha and beta, respectively 2003 In: Biochemical and biophysical research communications. - : Elsevier BV. - 0006-291X. ; 310:2, s. 589-593 Journal article (peer-reviewed)
7.	Stulnig, TM, et al. (author) Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue 2002 In: Molecular pharmacology. - : American Society for Pharmacology & Experimental Therapeutics (ASPET). - 0026-895X .- 1521-0111. ; 62:6, s. 1299-1305 Journal article (peer-reviewed)
8.	Toresson, G, et al. (author) Purification of functional full-length liver X receptor beta produced in Escherichia coli 2004 In: Protein expression and purification. - : Elsevier BV. - 1046-5928. ; 35:2, s. 190-198 Journal article (peer-reviewed)

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Result 1-8 of 8

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Type of publication: journal article (7); conference paper (1)

Type of content: peer-reviewed (7); other academic/artistic (1)

Author/Editor: Gustafsson, JA (4); Bjorkhem, I (3); Steffensen, KR (3); Dahlman-Wright, K (3); Schuster, G (3); Schuster, GU (3); show more...; Eggertsen, G (2); Gafvels, M (2); Olin, M (2); Andersson, U (2); Stulnig, TM (2); Li-Hawkins, J (2); Lund, E. (1); Seregard, S (1); Bengtsson, M (1); Ziegler, M. (1); Angelin, B (1); Sterner, Olov (1); Nilsson, M (1); Gao, H. (1); Parini, P (1); Diczfalusy, U (1); Pettersson, S (1); Rudling, M (1); Alberti, S (1); Feltkamp, D (1); Reimers, M (1); Toresson, G (1); Russell, DW (1); Schuster, V (1); Lund, EG (1); Russell, D (1); Ljunggren, J (1); Hugle, B. (1); Kamnaing, P (1); Tsopmo, Apollinaire (1); Tanifum, E A (1); Tchuendem, M H K (1); Tane, P (1); Ayafor, J F (1); Rattendi, D (1); Iwu, M M (1); Schuster, B (1); Bacchi, C (1); Luchtman-Jones, L (1); Tefs, K (1); Georgieva, M (1); Tait, CR (1); show less...

University: Karolinska Institutet (7); Lund University (1)

Language: English (8)

Research subject (UKÄ/SCB): Natural sciences (1)

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