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1.	Storeng, KT, et al. (author) Action to protect the independence and integrity of global health research 2019 In: BMJ global health. - : BMJ. - 2059-7908. ; 4:3, s. e001746- Journal article (other academic/artistic)
2.	Nevens, Frederik, et al. (author) A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis. 2016 In: The New England journal of medicine. - 1533-4406. ; 375:7, s. 631-43 Journal article (peer-reviewed)abstract Primary biliary cholangitis (formerly called primary biliary cirrhosis) can progress to cirrhosis and death despite ursodiol therapy. Alkaline phosphatase and bilirubin levels correlate with the risk of liver transplantation or death. Obeticholic acid, a farnesoid X receptor agonist, has shown potential benefit in patients with this disease.
3.	Tada, Hayato, et al. (author) Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history. 2015 In: European Heart Journal. - : Oxford University Press (OUP). - 1522-9645 .- 0195-668X. Journal article (peer-reviewed)abstract Genetic risk scores (GRSs) have been associated with coronary heart disease (CHD) in large studies. We asked whether expanding an established 27-variant GRS (GRS27) to a 50-variant GRS (GRS50) improved CHD prediction and whether GRSs are independent of self-reported family history of CHD.
4.	Melander, Olle, et al. (author) Low-Density Lipoprotein Particle Number Is Associated With Cardiovascular Events Among Those Not Classified Into Statin Benefit Groups 2015 In: Journal of the American College of Cardiology. - : Elsevier BV. - 0735-1097. ; 65:23, s. 2571-2573 Journal article (other academic/artistic)
5.	Shiffman, Dov, et al. (author) LDL subfractions are associated with incident cardiovascular disease in the Malmö Prevention Project Study 2017 In: Atherosclerosis. - : Elsevier BV. - 0021-9150. ; 263, s. 287-292 Journal article (peer-reviewed)abstract Background and aims After assessing the risk for cardiovascular disease (CVD) based on traditional risk factors, decisions concerning lipid lowering therapy might remain uncertain. To investigate whether lipoprotein subfraction levels could aid these decisions, we assessed the association between lipoprotein subfractions and CVD, after adjustment for traditional risk factors including standard lipids. Methods Using a case-cohort design, participants were randomly drawn from the Malmö Prevention Project (MPP), a population-based prospective study of 18,240 participants, and supplemented with additional incident CVD events (5764 participants, 1784 CVD events). Results Low density lipoprotein particle number (LDL-P) and individual subfractions ranging in size from very-small to large were associated with CVD (continuous p value (pcont) < 0.001) while adjusting for age, sex, hypertension, smoking, and diabetes. After further adjustment for LDL-C, HDL-C, and triglycerides, very small LDL subfraction (b) (LDL-VS (b)) remained associated with CVD (HR = 1.23, 95% CI, 1.06 to 1.43 for top vs. bottom quartile, pcont = 0.03). Among participants with low/intermediate risk [without diabetes and with LDL-C <3.36 mmol/L (<130 mg/dL)], the fully adjusted HR for LDL-small (top vs. bottom quartile) was 1.48 (95% CI 1.02 to 2.17, pcont = 0.03). Among those with very-high risk (>20% 10-year risk of CVD), LDL-VS(a) and LDL-VS(b) were associated with CVD in fully adjusted models (HR = 1.37, 95% CI 1.12 to 1.67 and HR = 1.28, 95% CI 1.07 to 1.53, respectively, pcont≤0.03). Conclusions Smaller LDL particles are associated with incident CVD independently of traditional risk factors, including standard lipids, in participants with low/intermediate and very-high risk, who might benefit from improved risk assessment.
6.	Shiffman, Dov, et al. (author) Use of low density lipoprotein particle number levels as an aid in statin treatment decisions for intermediate risk patients: A cost-effectiveness analysis 2016 In: BMC Cardiovascular Disorders. - : Springer Science and Business Media LLC. - 1471-2261. ; 16:1 Journal article (peer-reviewed)

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Result 1-6 of 6

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Type of publication: journal article (6)

Type of content: peer-reviewed (4); other academic/artistic (2)

Author/Editor: Melander, Olle (4); Doherty, T. (1); Strong, A. (1); Ahmad, A. (1); Atkins, S. (1); Schwarz, T. (1); show more...; Guichard, A. (1); Paul, E. (1); Hussain, S. (1); Kumar, P. (1); Wallace, L. (1); Cislaghi, B (1); Francis, JM (1); Mohammed, S (1); Norheim, OF (1); Biermann, O (1); Marschall, Hanns-Ulr ... (1); Marchal, B (1); Lonnroth, K (1); Greco, G. (1); Nilsson, Peter M (1); Dixon, J (1); Parker, M (1); Fischer, S. (1); Sarkar, N (1); Chapman, R. (1); Gordeev, VS (1); Hasselberg, M (1); Trauner, Michael (1); Hammarberg, K. (1); Palmer, J (1); Pai, M (1); Nelson, E. (1); Invernizzi, Pietro (1); Kathiresan, Sekar (1); Gautier, L. (1); Arthur, J (1); Delvaux, T (1); Van Belle, S (1); Seeley, J (1); Manzoor, M (1); Krauss, Ronald M. (1); Mendenhall, E (1); Abimbola, S (1); Filippi, V (1); Floreani, Annarosa (1); Shapiro, David (1); Burgess, R (1); George, A (1); Yakob, B. (1); show less...

University: Lund University (4); University of Gothenburg (1); Karolinska Institutet (1)

Language: English (6)

Research subject (UKÄ/SCB): Medical and Health Sciences (5)

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