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Träfflista för sökning "WFRF:(Simon JM) srt2:(1995-1999)"

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1.	ABE, O, et al. (author) EFFECTS OF RADIOTHERAPY AND SURGERY IN EARLY BREAST-CANCER - AN OVERVIEW OF THE RANDOMIZED TRIALS 1995 In: NEW ENGLAND JOURNAL OF MEDICINE. - 0028-4793. ; 333:22, s. 1444-1455 Journal article (other academic/artistic)
2.	Clarke, M, et al. (author) Ovarian ablation in early breast cancer: overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group 1996 In: Lancet (London, England). - 0140-6736. ; 348:9036, s. 1189-1196 Journal article (peer-reviewed)
3.	Dunham, I, et al. (author) The DNA sequence of human chromosome 22 1999 In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 402:6761, s. 489-495 Journal article (peer-reviewed)
4.	COLLINS, JE, et al. (author) A high-density YAC contig map of human chromosome 22 1995 In: Nature. - 0028-0836. ; 377:6547 Suppl, s. 367-379 Journal article (peer-reviewed)
5.	Simon, A, et al. (author) Cloning and characterization of two membrane proteins participating in retinoid transport and metabolism in the eye 1996 In: MOLECULAR BIOLOGY OF THE CELL. - 1059-1524. ; 7, s. 3461-3461 Conference paper (other academic/artistic)
6.	Simon, A, et al. (author) Intracellular localization and membrane topology of 11-cis retinol dehydrogenase in the retinal pigment epithelium suggest a compartmentalized synthesis of 11-cis retinaldehyde 1999 In: Journal of cell science. - : The Company of Biologists. - 0021-9533 .- 1477-9137. ; 112112 ( Pt 4):4, s. 549-558 Journal article (peer-reviewed)abstract 11-cis retinol dehydrogenase (EC 1.1.1.105) catalyses the last step in the biosynthetic pathway generating 11-cis retinaldehyde, the common chromophore of all visual pigments in higher animals. The enzyme is abundantly expressed in retinal pigment epithelium of the eye and is a member of the short chain dehydrogenase/reductase superfamily. In this work we demonstrate that a majority of 11-cis retinol dehydrogenase is associated with the smooth ER in retinal pigment epithelial cells and that the enzyme is an integral membrane protein, anchored to membranes by two hydrophobic peptide segments. The catalytic domain of the enzyme is confined to a lumenal compartment and is not present on the cytosolic aspect of membranes. Thus, the subcellular localization and the membrane topology of 11-cis retinol dehydrogenase suggest that generation of 11-cis retinaldehyde is a compartmentalized process.

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Result 1-6 of 6

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Type of publication: journal article (5); conference paper (1)

Type of content: peer-reviewed (4); other academic/artistic (2)

Author/Editor: Schumacher, M. (2); Brown, A. (2); Simon, R. (2); Jonat, W. (2); James, S. (2); Jackson, S. (2); show more...; Eriksson, U (2); Soderberg, M (2); Cross, M (2); Hill, C. (2); Collins, R (2); Nakamura, Y. (2); Martin, P. (2); Simon, A (2); Yoshida, M. (2); Abe, O (2); Abe, R (2); Enomoto, K (2); Kikuchi, K (2); Koyama, H (2); Nomura, Y (2); Uchino, J (2); Haybittle, JL (2); Davies, C (2); Harvey, VJ (2); Holdaway, TM (2); Kay, RG (2); Mason, BH (2); Forbes, JF (2); Jakesz, R (2); Yosef, HMA (2); Focan, C (2); Lobelle, JP (2); Peek, U (2); Oates, GD (2); Powell, J (2); Ragaz, J (2); Cirrincione, C (2); Norton, L (2); Weiss, RB (2); Baum, M (2); Cuzick, J (2); Houghton, J (2); Riley, D (2); Gordon, NH (2); Davis, HL (2); Naja, A (2); Dubois, JB (2); Delozier, T (2); Rambert, P (2); show less...

University: Karolinska Institutet (6)

Language: English (6)

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