| 1. |
- Adcox, K, et al.
(author)
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Measurement of single electrons and implications for charm production in Au+Au collisions at root(NN)-N-S=130 GeV
- 2002
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In: Physical Review Letters. - 1079-7114. ; 88:19
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Journal article (peer-reviewed)abstract
- Transverse momentum spectra of electrons from Au+Au collisions at roots(NN) = 130 GeV have been measured at midrapidity by the PHENIX experiment at the Relativistic Heavy Ion Collider. The spectra show an excess above the background from photon conversions and light hadron decays. The electron signal is consistent with that expected from semileptonic decays of charm. The yield of the electron signal dN(e)/dy for p(T) > 0.8 GeV/c is 0.025 +/- 0.004(stat) +/- 0.010( syst) in central collisions, and the corresponding charm cross section is 380 +/- 60(stat) +/- 200(syst ) mub per binary nucleon-nucleon collision.
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| 2. |
- Abreu, P, et al.
(author)
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Measurement of the e(+)e(-)->gamma gamma(gamma) cross section at the LEP energies
- 1998
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In: PHYSICS LETTERS B. - : ELSEVIER SCIENCE BV. - 0370-2693. ; 433:3-4, s. 429-440
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Journal article (other academic/artistic)abstract
- The total and the differential cross-sections for the reaction e(+)e(-) --> gamma gamma(gamma) have been measured with the DELPHI detector at LEP at centre-of-mass energies from 130 to 183 GeV for an integrated luminosity of 78.19 pb(-1). The results agre
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| 3. |
- Abreu, P, et al.
(author)
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Single intermediate vector boson production in e(+)e(-) collisions at root s=183 and 189 GeV
- 2001
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In: PHYSICS LETTERS B. - : ELSEVIER SCIENCE BV. - 0370-2693. ; 515:3-4, s. 238-254
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Journal article (peer-reviewed)abstract
- The cross sections for the production of single charged and neutral intermediate vector bosons were measured using integrated luminosities of 52 pb(-1) and 154 pb(-1) collected by the experiment at centre-of-mass energies of 182.6 GeV and 188.6 GeV, respe
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| 4. |
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| 5. |
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| 6. |
- Adler, Sven
(author)
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Modelling distribution of common scoter (Melanitta nigra) by its predominant prey, the American razor clam (Ensis leei) and hydrodynamic parameters
- 2019
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In: Estuarine, Coastal and Shelf Science. - : Elsevier BV. - 0272-7714 .- 1096-0015. ; 225
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Journal article (peer-reviewed)abstract
- The non-breeding distribution of common scoter (Melanitta nigra), which occur in high densities offshore from the eastern Wadden Sea, has been well documented in recent decades, but factors influencing these patterns remain poorly known. We investigated the prey choice of 88 common scoter using stomach contents of beached birds collected over a period of 12 years. We then used benthos data and hydrodynamic parameters to model the June-September distribution patterns during the flightless period of common scoter based on transect count data off the north-eastern German Wadden Sea.Benthic fauna biomass in areas used by common scoter was higher than in areas where the species was absent. American razor clam (Ensis leei) invaded the Wadden Sea during the end of the 1970s and was the most common prey, both in benthos samples from below feeding common scoter and in stomach samples. The relatively high flesh to shell ratio of the American razor clam makes it the most attractive available prey item for common scoter.The abundance of American razor clams explained the distribution of scoter to a high degree, although the best model fit included negative effects of water depth and positive effects of bed shear stress intensity on scoter abundance. Our data show that the neobiotic American razor clams have become an important part of the diet of these sea ducks, whereas the cut trough shell (Spisula subtruncata) was of substantially lesser importance than expected from historical data. Our study shows the ability of a top avian predator to respond to novel developments in bivalve prey availability over periods of a few decades.
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| 7. |
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| 8. |
- Obieglo, K, et al.
(author)
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Chronic Gastrointestinal Nematode Infection Mutes Immune Responses to Mycobacterial Infection Distal to the Gut
- 2016
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In: Journal of immunology (Baltimore, Md. : 1950). - : The American Association of Immunologists. - 1550-6606 .- 0022-1767. ; 196:5, s. 2262-2271
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Journal article (peer-reviewed)abstract
- Helminth infections have been suggested to impair the development and outcome of Th1 responses to vaccines and intracellular microorganisms. However, there are limited data regarding the ability of intestinal nematodes to modulate Th1 responses at sites distal to the gut. In this study, we have investigated the effect of the intestinal nematode Heligmosomoides polygyrus bakeri on Th1 responses to Mycobacterium bovis bacillus Calmette–Guérin (BCG). We found that H. polygyrus infection localized to the gut can mute BCG-specific CD4+ T cell priming in both the spleen and skin-draining lymph nodes. Furthermore, H. polygyrus infection reduced the magnitude of delayed-type hypersensitivity (DTH) to PPD in the skin. Consequently, H. polygyrus–infected mice challenged with BCG had a higher mycobacterial load in the liver compared with worm-free mice. The excretory–secretory product from H. polygyrus (HES) was found to dampen IFN-γ production by mycobacteria-specific CD4+ T cells. This inhibition was dependent on the TGF-βR signaling activity of HES, suggesting that TGF-β signaling plays a role in the impaired Th1 responses observed coinfection with worms. Similar to results with mycobacteria, H. polygyrus–infected mice displayed an increase in skin parasite load upon secondary infection with Leishmania major as well as a reduction in DTH responses to Leishmania Ag. We show that a nematode confined to the gut can mute T cell responses to mycobacteria and impair control of secondary infections distal to the gut. The ability of intestinal helminths to reduce DTH responses may have clinical implications for the use of skin test–based diagnosis of microbial infections.
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| 9. |
- Hilletofth, Per
(author)
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Differentiation focused supply chain design
- 2012
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In: Industrial management & data systems. - : Emerald Group Publishing Limited. - 0263-5577 .- 1758-5783. ; 112:9, s. 1274-1291
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Journal article (peer-reviewed)abstract
- Purpose – The purpose of this paper is to develop a framework for differentiation focused supply chain design (SCD).Design/methodology/approach – This research uses a literature review and case study approach to develop a framework for differentiation focused SCD. The proposed framework has been developed based on the literature review and evaluated against the case study. The case study describes SCD at two Swedish companies; one from the appliance industry and the other from the furniture industry, both having a significant international presence. Empirical data have been collected, mainly from in-depth and semi-structured interviews with key persons representing senior and middle management in the case companies.Findings – This research suggests that differentiation-focused SCD can be organized into a five-stage process. It is essential that this process is aligned with new product development (NPD), so they exchange information, and operate based on the same segmentation model. The main benefits of a differentiated supply chain are enhanced competitiveness, as supply chain management (SCM) changes from being a cost center to being a value generating function, and increased profitability, by allowing differentiated customer needs to be satisfied cost-efficiently. To succeed with developing a differentiated supply chain, logisticians must be extensively involved with both the NPD process and the strategic marketing process.Research limitations/implications – Current models of SCD are simplistic and not well developed. By combining theory with practical applications, this research provides researchers and decision makers with detailed tools for developing a differentiation-focused SCD process. The research is explorative in nature therefore empirical data from similar and other research settings should be gathered to reinforce the validity of the findings.Practical implications – This research provides knowledge and insights on how a differentiated supply chain may be developed. The main implication is that SCD needs to be closely aligned with NPD and marketing in order to gain competitive advantage. Companies may also be able to employ labor closer to the consumption market by focusing on supply chain differentiation.Originality/value – This research contributes by developing a process for differentiation-focused SCD, and by demonstrating the main benefits and requirements of a differentiated supply chain.
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| 10. |
- Walser, Marion, 1961, et al.
(author)
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Local overexpression of GH and GH/IGF1 effects in the adult mouse hippocampus.
- 2012
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In: The Journal of endocrinology. - 1479-6805. ; 215:2, s. 257-68
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Journal article (peer-reviewed)abstract
- GH therapy improves hippocampal functions mainly via circulating IGF1. However, the roles of local GH and IGF1 expression are not well understood. We investigated whether transgenic (TG) overexpression in the adult brain of bovine GH (bGH) under the control of the glial fibrillary acidic protein (GFAP) promoter affected cellular proliferation and the expression of transcripts known to be induced by systemic GH in the hippocampus. Cellular proliferation was examined by 5-bromo-2'-deoxyuridine immunohistochemistry. Quantitative PCR and western blots were performed. Although robustly expressed, bGH-Tg did not increase either cell proliferation or survival. However, bGH-Tg modestly increased Igf1 and Gfap mRNAs, whereas other GH-associated transcripts were unaffected, i.e. the GH receptor (Ghr), IGF1 receptor (Igf1r), 2',3'-cyclic nucleotide 3'-phosphodiesterase (Cnp), ionotropic glutamate receptor 2a (Nr2a (Grin2a)), opioid receptor delta (Dor), synapse-associated protein 90/postsynaptic density-95-associated protein (Sapap2 (Dlgap2)), haemoglobin beta (Hbb) and glutamine synthetase (Gs (Glul)). However, IGF1R was correlated with the expression of Dor, Nr2a, Sapap2, Gs and Gfap. In summary, although local bGH expression was robust, it activated local IGF1 very modestly, which is probably the reason for the low response of previous GH-associated response parameters. This would, in turn, indicate that hippocampal GH is less important than endocrine GH. However, as most transcripts were correlated with the expression of IGF1R, there is still a possibility for endogenous circulating or local GH to act via IGF1R signalling. Possible reasons for the relative bio-inactivity of bGH include the bell-shaped dose-response curve and cell-specific expression of bGH.
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