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- Axelsson, Bertil, et al.
(författare)
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Analgesic effect of paracetamol on cancer related pain in concurrent strong opioid therapy. A prospective clinical study
- 2008
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Ingår i: Acta Oncologica. - : Informa UK Limited. - 0284-186X .- 1651-226X. ; 47:5, s. 891-895
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Tidskriftsartikel (refereegranskat)abstract
- Introduction. In palliative cancer care, when approaching death, swallowing difficulties and the burden of tablet intake frequently makes us reconsider each individual drug prescribed. Through the last two decades the routine of always combining a strong opioid with paracetamol has been widely spread in Sweden. Clinical experience has challenged this routine as many patients seem to manage equally well without paracetamol. To find out whether this might be of clinical importance, we wanted to perform a more systematic registration. Material and methods. Thirty-four incurable cancer patients with well controlled pain (NRS 4), treated by specialised palliative home care teams, with ongoing medication with the strong opioid paracetamol combination was recruited to this prospective clinical study. The effect of completely stopping paracetamol medication was evaluated four days later at follow-up. Results. At follow-up nine patients (26%) felt more pain compared to when they entered the study, two patients (6%) felt less pain and 23 (68%) felt no difference. When asked about their preference about future paracetamol treatment 18 patients (53%) wanted to stop taking it, six patients (18%) wanted to continue with regular paracetamol medication as before, and ten patients (29%) wanted to take paracetamol as needed. No clinical predictors of paracetamol response could be identified. Discussion. The results of this study indicate that a critical evaluation, in every patient, of the subjective additive analgesic effect of paracetamol in concurrent strong opioid therapy is advisable and that stopping paracetamol medication not necessarily implies increased pain. Rather in some patients the cessation of paracetamol medication is experienced as a relief as pain control is maintained with a lesser tablet burden.
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- Eide, C, et al.
(författare)
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Mixed Reality : to apply for “urgent education/performance” or for rehearsal only?
- 2009
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Konferensbidrag (refereegranskat)abstract
- Background: The Swedish Armed Forces are in a new suit concerning peacekeeping missions abroad. In the future the Forces may have less Medical specialists that are conducive to the use of more Technical supporting system. Here we suggest a Mixed Reality supporting system for convoluted medicine technical performance. Mixed Reality involves the merging of real and virtual worlds. The user utilizes a head mounted or a handheld visual display presenting texts, virtual objects, animation sequences, audio and environmental features as incorporated into the real environments. Summary of work: We conducted an evaluation study in which ten participants used Mixed Reality technology, compared to written instructions with a picture as support for executing tasks. The tasks were to perform the procedures of ”power up” and to unitize a ventilator circuit assembly for the LSTAT® (Life Support for Trauma And Transport, a Platform for medical evacuation of a patient/wounded soldier.) Summary of results: The Mixed Reality technology was in general considered beneficial and there were favourable reactions in these tasks, compared to the written instructions.
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- Kamel, H., et al.
(författare)
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Characterization of ink adhesion failure; effect of pre-dampening of carbonate containing coatings
- 2008
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Ingår i: TAPPI Advanced Coating Fundamentals Symposium Proceedings. - : TAPPI Press. ; , s. 228-241
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Konferensbidrag (refereegranskat)abstract
- To attain an improved knowledge about ink adhesion during offset printing we have developed a laboratory procedure to measure adhesion failure between ink and coated paper during ink setting. This paper describes the technique and a special case, where a normal coating and a coating with excess dispersing agent, in the form of sodium polyacrylate, have been printed. Characterization of the areas where the adhesion had failed at the pull-off points after tack testing was done by determining "white" spots in the retained print using image analysis. The "white" spots represent areas where ink has detached from the coating after contact with a rubber coated cylinder. This area is referred to as adhesion failure area (AFA). A minimum in AFA at the point of maximum in tack force was found for both coatings where the print was applied onto dried coating. When the coatings, however, were pre-damped, AFA increased on the normal coating over a short time period, independent of the dampening level. For the coating with excess dispersant, on the other hand, the higher dampening level strongly increased the AFA. The strong impact of excess dispersing agent in this work may be explained by a number of related effects, including increased polarity of the coating surface, and an associated moisture layer, and an effective reduction of fine pores due to water-swelling polyacrylate that blocks these pores.
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