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- Alwis, Gayani, et al.
(author)
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Normative Calcaneal Quantitative Ultrasound Data as an Estimation of Skeletal Development in Swedish Children and Adolescents.
- 2010
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In: Calcified Tissue International. - : Springer Science and Business Media LLC. - 1432-0827 .- 0171-967X. ; 87, s. 493-506
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Journal article (peer-reviewed)abstract
- We present age- and gender-specific normative bone status data evaluated by quantitative ultrasound (QUS) in the calcaneus with the Lunar Achilles device and compare these estimates with bone mineral content (BMC) and bone mineral density (BMD) estimated by dual X-ray absorptiometry (DXA). Included were a sample of 518 population-based collected Swedish girls and 558 boys aged 6-19 years. QUS measurements included speed of sound (SOS), broadband ultrasound attenuation (BUA), and stiffness index (SI) in the calcaneus. DXA measurements included BMC and BMD in the femoral neck (FN), lumbar spine (L2-L4), and total body (TB). Height and weight were measured with standard equipment. Age, height, and weight were significantly associated with SOS, BUA, and SI. Compared to SOS, in both girls and boys there was a higher correlation between BUA and FN BMC (r = 0.71 and r = 0.73, respectively), FN BMD (r = 0.68 and r = 0.67, respectively), L2-L4 BMC (r = 0.70 and r = 0.64, respectively), L2-L4 BMD (r = 0.69 and r = 0.64, respectively), TB BMC (r = 0.76 and r = 0.75, respectively), and TB BMD (r = 0.74 and r = 0.74, respectively). The correlations between SOS and FN BMC (r = 0.38 and r = 0.52, respectively), FN BMD (r = 0.41 and r = 0.52, respectively), L2-L4 BMC (r = 0.31 and r = 0.40, respectively), L2-L4 BMD (r = 0.32 and r = 0.41, respectively), TB BMC (r = 0.42 and r = 0.49, respectively), and TB BMD (r = 0.48 and r = 0.54, respectively) were lower, although still significant (all P < 0.001). BUA seems to be the QUS parameter that best resembles the changes in BMC during growth.
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- Bolin, Niklas, 1977-
(author)
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Målsättning riksdagen : Ett aktörsperspektiv på nya partiers inträde i det nationella parlamentet
- 2012
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Doctoral thesis (other academic/artistic)abstract
- During much of the 20th century, the national party systems of Western Europe remained largely unchanged. However, beginning in the 1970s, these frozen party systems slowly started to melt. As the number of parties has increased, the question of what explains new party entrance has also attracted more scholarly interest. Despite this increased attention, the study of new political parties still suffers from a structuralist bias. The implication is that the fates of new parties are decided almost exclusively by external factors. Some scholars focus on the institutional environment; others emphasize sociological explanations, such as the formation of new cleavages in society. Yet such non-actor-centred perspectives risk being excessively deterministic. They also struggle to explain why some parties succeed in gaining entrance to legislatures while others, seemingly under the same external circumstances, fail. In this thesis, therefore, a new way to study parties and their path to parliament is proposed. Starting with the notion that external conditions alone cannot explain new party entrance, the thesis takes an agency-based perspective. Three sets of strategies are identified as being important means for a party to influence its chances of getting into parliament. They concern the party's resources, its political project and its external relations. In what ways can supply and management of resources, policies and relations with other parties affect the potential for becoming a parliamentary party? Through four in-depth case studies of new entrants into the Swedish national parliament, the Riksdag, the thesis concludes that there are some important commonalities in their paths to parliament. Especially with regard to their resources and their political project, the empirical evidence supports the initial premise: new party entrance is unthinkable without successful strategic behaviour.
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- Choong, Eva, et al.
(author)
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Sex difference in formation of propofol metabolites : a replication study
- 2013
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In: Basic & Clinical Pharmacology & Toxicology. - : Wiley. - 1742-7835 .- 1742-7843. ; 113:2, s. 126-131
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Journal article (peer-reviewed)abstract
- Women recover faster from propofol anaesthesia and have been described to have a higher incidence of awareness during surgery, compared to men - an effect that may be inherent in sex differences in propofol metabolism. In an observational study, 98 ASA I-II patients treated with continuous propofol infusion were recruited. The associations between sex and CYP2B6 and UGT1A9 polymorphisms with dose- and weight-adjusted area under the total plasma level time curves (AUC) for propofol, and its metabolites propofol glucuronide (PG), 4-hydroxypropofol (OHP) and hydroxyl glucuronide metabolites 4-hydroxypropofol-1-O-β-D-glucuronide (Q1G) and 4-hydroxypropofol-4-O-β-D-glucuronide (Q4G), were analysed. Significantly higher AUC of PG (1.3 times, p = 0.03), Q1G (2.9 times, p < 0.001), Q4G (2.4 times, p < 0.01) and OHP (4.6 times, p = 0.01) were found in women (n = 53) than in men (n = 45) after intravenous infusion of propofol using target-controlled infusion system. There was, however, no significant impact of gene polymorphisms on propofol biotransformation. The results, which are supported by a previous pilot study using a propofol bolus dose, suggest that, compared to men, more rapid propofol metabolism may occur in women - a factor that may contribute to the mentioned differences in the efficacy of propofol anaesthesia between male and female patients.
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- Finnveden, Göran, et al.
(author)
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Policy instruments towards a sustainable waste management
- 2013
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In: Sustainability. - Basel : MDPI AG. - 2071-1050. ; 5:3, s. 841-881
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Journal article (peer-reviewed)abstract
- The aim of this paper is to suggest and discuss policy instruments that could lead towards a more sustainable waste management. The paper is based on evaluations from a large scale multi-disciplinary Swedish research program. The evaluations focus on environmental and economic impacts as well as social acceptance. The focus is on the Swedish waste management system but the results should be relevant also for other countries. Through the assessments and lessons learned during the research program we conclude that several policy instruments can be effective and possible to implement. Particularly, we put forward the following policy instruments: “Information”; “Compulsory recycling of recyclable materials”; “Weight-based waste fee in combination with information and developed recycling systems”; “Mandatory labeling of products containing hazardous chemicals”, “Advertisements on request only and other waste minimization measures”; and “Differentiated VAT and subsidies for some services”. Compulsory recycling of recyclable materials is the policy instrument that has the largest potential for decreasing the environmental impacts with the configurations studied here. The effects of the other policy instruments studied may be more limited and they typically need to be implemented in combination in order to have more significant impacts. Furthermore, policy makers need to take into account market and international aspects when implementing new instruments. In the more long term perspective, the above set of policy instruments may also need to be complemented with more transformational policy instruments that can significantly decrease the generation of waste.
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- Haikonen, Kalle, et al.
(author)
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Characteristics of the Operational Noise from Full Scale Wave Energy Converters in the Lysekil Project : Estimation of Potential Environmental Impacts
- 2013
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In: Energies. - : MDPI AG. - 1996-1073. ; 6:5, s. 2562-2582
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Journal article (peer-reviewed)abstract
- Wave energy conversion is a clean electric power production technology. During operation there are no emissions in the form of harmful gases. However there are unsolved issues considering environmental impacts such as: electromagnetism; the artificial reef effect and underwater noise. Anthropogenic noise is increasing in the oceans worldwide and wave power will contribute to this sound pollution in the oceans; but to what extent? The main purpose of this study was to examine the noise emitted by a full scale operating Wave Energy Converter (WEC) in the Lysekil project at Uppsala University in Sweden. A minor review of the hearing capabilities of fish and marine mammals is presented to aid in the conclusions of impact from anthropogenic sound. A hydrophone was deployed to the seabed in the Lysekil research site park at distance of 20 and 40 m away from two operational WECs. The measurements were performed in the spring of 2011. The results showed that the main noise was a transient noise with most of its energy in frequencies below 1 kHz. These results indicate that several marine organisms (fish and mammals) will be able to hear the operating WECs of a distance of at least 20 m.
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- Haikonen, Kalle, 1978-, et al.
(author)
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Hydroacoustic measurements of the radiated noise from Wave Energy Converters in the Lysekil project and project WESA
- 2013
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In: Proceedings UA 2013. - 9786188072503 ; , s. 199-209
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Conference paper (peer-reviewed)abstract
- Field measurements of the hydroacoustic noise from Wave Energy Converters (WECs) in the Lysekil project at Uppsala University and the Project WESA (joint effort between Uppsala University (Lead Partner), Ålands Teknikkluster r.f. and University of Turku) are presented. Anthropogenic noise is increasing in the oceans world wide and wave energy conversion may contribute to this noise, but to what extent? The main objective in this study is to examine the noise from full scale operating WECs in the Lysekil and project WESA. Acoustic measurements were made in order to be able to estimate potential environmental impact. Submersible recording devices (SRD) were deployed at 1 m from WECs at a depth of approximately 24 meters. Both WECs are a full scale point absorber with a directly driven linear generator, placed on gravitation foundations at the seabed with a connected buoy at the surface that absorbs energy from the heaving waves. The SRDs used to measure the noise from the WECs, consists of a SM2-recorder from Wildlife Acoustics and hydrophones from High Tech Inc. (HTI 96 MIN and HTI 99 HF). Measurements at in the Lysekil project were carried out in the spring of 2013 and in the project WESA in Jan-Feb of 2012. Preliminary results show that the main operating noise radiated from the WEC are short transients with instant rise time when the translator moves past the stator and when the stator hits the end stop springs of the generator. Most of the power in the noise is between 20 – 1000 Hz.
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