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Träfflista för sökning "WFRF:(Sundin Anders) srt2:(1995-1999)"

Search: WFRF:(Sundin Anders) > (1995-1999)

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  • Sundin, Johanna, et al. (author)
  • High yield direct 76Br-bromination of monoclonal antibodies using Cloramine-T
  • 1999
  • In: Nuclear Medicine and Biology. - 0969-8051 .- 1872-9614. ; 26:8, s. 923-929
  • Journal article (peer-reviewed)abstract
    • Monoclonal antibody (MAb) A33 was labeled with the positron emitter 76Br (T(1/2) = 16.2 h). Direct labeling was done using the conventional chloramine-T method. After optimization of the labeling conditions, a maximum yield (mean +/- max error) of 77 +/- 2% was obtained at pH 6.8. In vitro binding of 76Br-A33 to SW1222 colonic cancer cells showed that the immunoreactivity was retained. Also, the MAbs 38S1 and 3S193 and the peptide hEGF were 76Br-labeled, resulting in labeling yields (mean +/- max error) of 75 +/- 3%, 63 +/- 4%, and 73 +/- 0.1%, respectively. We conclude that antibodies and peptides can be labeled conveniently with 76Br for the purpose of whole-body tumour imaging by positron emission tomography.
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  • Result 1-10 of 61
Type of publication
journal article (52)
conference paper (7)
other publication (1)
book chapter (1)
Type of content
peer-reviewed (53)
other academic/artistic (8)
Author/Editor
Sundin, Anders (55)
Långström, Bengt (16)
Lundqvist, Hans (15)
Carlsson, Jörgen (14)
Bergström, Mats (11)
Tolmachev, Vladimir (10)
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Ahlström, Håkan (9)
Magnusson, Anders (9)
Bergman, Antonina (8)
Eriksson, Barbro (7)
Sperling, Lena (7)
Öberg, Kjell (6)
Akselsson, Roland (5)
Engström, Tomas, 195 ... (5)
Kadefors, Roland, 19 ... (4)
Hansson, Gert-Åke (4)
Eriksson, B (3)
Johansson, C. (3)
Gedda, Lars (3)
Langstrom, Bengt (3)
Hansson, Lars (3)
Lubberink, Mark (3)
Sörensen, Jens (2)
Mathiassen, Svend Er ... (2)
Ahlstrom, Håkan (2)
Orlova, Anna (2)
Moore, K (2)
Winkel, Jörgen, 1946 (2)
Watanabe, Y. (2)
Palm, Rainer (2)
Koziorowski, Jacek (2)
Holmqvist, K. (2)
Medbo, Lars, 1957 (2)
Bergstrom, Mats (2)
Oberg, Kjell (2)
Langstrom, B (2)
Holmqvist, Kenneth (2)
Bjurling, Pernilla (2)
Sundin, Johanna (2)
Skogseid, Britt (2)
Hartvig, Per (2)
Kadefors, Roland (2)
Hellman, P (2)
Valind, Sven (2)
Fasth, K-J (2)
Lilja, A (2)
Graf, Wilhelm (2)
Mahteme, Haile (2)
Sjölander, S (2)
Bergstrom, M (2)
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University
Uppsala University (52)
Chalmers University of Technology (5)
Lund University (4)
Karolinska Institutet (2)
University of Skövde (1)
Language
English (57)
Swedish (3)
Italian (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (20)
Engineering and Technology (5)

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