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Träfflista för sökning "WFRF:(Taddei A) srt2:(2001-2004)"

Search: WFRF:(Taddei A) > (2001-2004)

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1.
  • Giraud, Antoine, et al. (author)
  • Costs and benefits of high mutation rates : adaptive evolution of bacteria in the mouse gut.
  • 2001
  • In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 291:5513, s. 2606-8
  • Journal article (peer-reviewed)abstract
    • We have shown that bacterial mutation rates change during the experimental colonization of the mouse gut. A high mutation rate was initially beneficial because it allowed faster adaptation, but this benefit disappeared once adaptation was achieved. Mutator bacteria accumulated mutations that, although neutral in the mouse gut, are often deleterious in secondary environments. Consistently, the competitiveness of mutator bacteria is reduced during transmission to and re-colonization of similar hosts. The short-term advantages and long-term disadvantages of mutator bacteria could account for their frequency in nature.
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2.
  • Giraud, A, et al. (author)
  • The rise and fall of mutator bacteria.
  • 2001
  • In: Current Opinion in Microbiology. - 1369-5274 .- 1879-0364. ; 4:5, s. 582-5
  • Journal article (peer-reviewed)abstract
    • Bacteria with elevated mutation rates are frequently found among natural isolates. This is probably because of their ability to generate genetic variability, the substrate for natural selection. However, such high mutation rates can lead to the loss of vital functions. The evolution of bacterial populations may happen through alternating periods of high and low mutation rates. The cost and benefits of high mutation rates in the course of bacterial adaptive evolution are reviewed.
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  • Result 1-2 of 2
Type of publication
journal article (2)
Type of content
peer-reviewed (2)
Author/Editor
Matic, I (2)
Radman, M (2)
Taddei, F (2)
Giraud, Antoine (1)
Fons, M (1)
Tenaillon, O (1)
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Clara, A (1)
Giraud, A (1)
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University
Uppsala University (2)
Language
English (2)
Research subject (UKÄ/SCB)
Natural sciences (2)
Year
2001 (2)

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