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Träfflista för sökning "WFRF:(Thomas David B) srt2:(2020-2024)"

Search: WFRF:(Thomas David B) > (2020-2024)

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1.
  • Niemi, MEK, et al. (author)
  • 2021
  • swepub:Mat__t
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  • Kanai, M, et al. (author)
  • 2023
  • swepub:Mat__t
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  • Kattge, Jens, et al. (author)
  • TRY plant trait database - enhanced coverage and open access
  • 2020
  • In: Global Change Biology. - : Wiley-Blackwell. - 1354-1013 .- 1365-2486. ; 26:1, s. 119-188
  • Journal article (peer-reviewed)abstract
    • Plant traits-the morphological, anatomical, physiological, biochemical and phenological characteristics of plants-determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits-almost complete coverage for 'plant growth form'. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait-environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives.
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  • Abbafati, Cristiana, et al. (author)
  • 2020
  • Journal article (peer-reviewed)
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10.
  • Mullins, Niamh, et al. (author)
  • Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
  • 2022
  • In: Biological Psychiatry. - : Elsevier. - 0006-3223 .- 1873-2402. ; 91:3, s. 313-327
  • Journal article (peer-reviewed)abstract
    • BACKGROUND: Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders.METHODS: We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) cases and 519,961 controls in the International Suicide Genetics Consortium (ISGC). The GWAS of SA was conditioned on psychiatric disorders using GWAS summary statistics via multitrait-based conditional and joint analysis, to remove genetic effects on SA mediated by psychiatric disorders. We investigated the shared and divergent genetic architectures of SA, psychiatric disorders, and other known risk factors.RESULTS: Two loci reached genome-wide significance for SA: the major histocompatibility complex and an intergenic locus on chromosome 7, the latter of which remained associated with SA after conditioning on psychiatric disorders and replicated in an independent cohort from the Million Veteran Program. This locus has been implicated in risk-taking behavior, smoking, and insomnia. SA showed strong genetic correlation with psychiatric disorders, particularly major depression, and also with smoking, pain, risk-taking behavior, sleep disturbances, lower educational attainment, reproductive traits, lower socioeconomic status, and poorer general health. After conditioning on psychiatric disorders, the genetic correlations between SA and psychiatric disorders decreased, whereas those with nonpsychiatric traits remained largely unchanged.CONCLUSIONS: Our results identify a risk locus that contributes more strongly to SA than other phenotypes and suggest a shared underlying biology between SA and known risk factors that is not mediated by psychiatric disorders.
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  • Result 1-10 of 451
Type of publication
journal article (422)
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peer-reviewed (436)
other academic/artistic (8)
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Author/Editor
Ekelöf, Tord (163)
Brenner, Richard (161)
Bergeås Kuutmann, El ... (160)
Ferrari, Arnaud, 197 ... (160)
Gonzalez Suarez, Reb ... (160)
Mathisen, Thomas (160)
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Ellert, Mattias (159)
Ellajosyula, Venugop ... (159)
Zwalinski, L. (158)
Ripellino, Giulia (155)
Strandberg, Jonas (149)
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Backman, Filip, 1991 ... (136)
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Valdés Santurio, Edu ... (134)
Bohm, Christian, 194 ... (132)
Shaheen, Rabia (127)
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Ördek, Serhat (114)
Asimakopoulou, Eleni ... (110)
Milstead, David A., ... (104)
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Hellman, Sten, 1956- (103)
Lou, Xuanhong, 1995- (103)
Silverstein, Samuel ... (103)
Sjölin, Jörgen, 1968 ... (103)
Steentoft, Jonas (103)
Clément, Christophe, ... (102)
Dunne, Katherine, 19 ... (102)
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Strandberg, Sara, 19 ... (98)
Strübig, Antonia, 19 ... (98)
Leopold, Alexander (96)
Lytken, E. (93)
Hedberg, V. (92)
Konya, B. (92)
Poettgen, R. (92)
Smirnova, O. (92)
Shope, David R. (92)
Richter, Stefan, 198 ... (91)
Aad, G (88)
Kim, Dongwon, 1989- (87)
Lee, Suhyun (86)
Skorda, E. (84)
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Royal Institute of Technology (161)
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Umeå University (54)
University of Gothenburg (36)
Linköping University (22)
Swedish University of Agricultural Sciences (17)
Luleå University of Technology (6)
Stockholm School of Economics (6)
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Högskolan Dalarna (2)
Swedish Museum of Natural History (2)
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IVL Swedish Environmental Research Institute (1)
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Language
English (448)
Swedish (3)
Research subject (UKÄ/SCB)
Natural sciences (307)
Medical and Health Sciences (130)
Social Sciences (25)
Engineering and Technology (18)
Agricultural Sciences (4)
Humanities (4)

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