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Träfflista för sökning "WFRF:(Tolockiene Egle) srt2:(2010-2014)"

Search: WFRF:(Tolockiene Egle) > (2010-2014)

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  • Toriola, Adetunji T., et al. (author)
  • Free beta- human chorionic gonadotropin, total human chorionic gonadotropin and maternal risk of breast cancer
  • 2014
  • In: Future Oncology. - 1479-6694 .- 1744-8301. ; 10:3, s. 377-384
  • Journal article (peer-reviewed)abstract
    • Background: We investigated whether the free -human chorionic gonadotropin (free -hCG) would provide additional information to that provided by total hCG alone and thus be useful in future epidemiological studies relating hCG to maternal breast cancer risk. Materials & methods: Cases (n = 159) and controls (n = 286) were a subset of our previous study within the Northern Sweden Maternity Cohort on total hCG during primiparous pregnancy and breast cancer risk. Results: The associations between total hCG (hazard ratio: 0.79; 95% CI: 0.49-1.27), free -hCG (hazard ratio: 0.85; 95% CI: 0.33-2.18) and maternal risk of breast cancer were very similar in all analyses and mutual adjustment for either one had minor effects on the risk estimates. Conclusion: In the absence of a reliable assay on intact hCG, total hCG alone can be used in epidemiological studies investigating hCG and breast cancer risk, as free -hCG does not appear to provide any additional information.
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