SwePub
Sök i SwePub databas

  Extended search

Träfflista för sökning "WFRF:(Turesson Ingemar) srt2:(1990-1994)"

Search: WFRF:(Turesson Ingemar) > (1990-1994)

  • Result 1-2 of 2
Sort/group result
   
EnumerationReferenceCoverFind
1.
  •  
2.
  • Fioretos, Thoas, et al. (author)
  • Clinical impact of breakpoint position within M-bcr in chronic myeloid leukemia
  • 1993
  • In: Leukemia. - 1476-5551. ; 7:8, s. 1225-1231
  • Journal article (peer-reviewed)abstract
    • We have analyzed the M-bcr breakpoint position in 133 Philadelphia-positive chronic myeloid leukemia patients and correlated the findings with clinical, hematologic, and cytogenetic data. We also investigated the splicing pattern of the BCR-ABL mRNA in 30 patients, using reverse transcriptase PCR. No statistically significant differences were found between breakpoint position within M-bcr and clinical parameters at diagnosis, the karyotypic evolution pattern, or the leukemic phenotype during blast crisis. Furthermore, the breakpoint position within M-bcr did not correlate with the duration of chronic phase or survival time. When the splicing pattern of the BCR-ABL mRNA was compared with the results of the genomic breakpoint mapping, it was found that approximately 60% (8/14) of the patients with a 5' break expressed b2a2 fusion mRNA, whereas all patients (10/10) with a 3' break expressed b3a2 BCR-ABL mRNA.
  •  
Skapa referenser, mejla, bekava och länka
  • Result 1-2 of 2

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view