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- Folia, V, et al.
(author)
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Implicit learning and dyslexia
- 2008
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In: Annals of the New York Academy of Sciences. - : Wiley. - 1749-6632 .- 0077-8923. ; 1145, s. 132-150
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Journal article (peer-reviewed)
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| 3. |
- Hemmingsson, Erik, et al.
(author)
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Increased physical activity in abdominally obese women through support for changed commuting habits : a randomized clinical trial
- 2009
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In: International Journal of Obesity. - : Springer Science and Business Media LLC. - 0307-0565 .- 1476-5497. ; 33:6, s. 645-652
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Journal article (peer-reviewed)abstract
- Background: Abdominally obese women can reduce their health risk through regular physical activity. There is, however, little evidence on the effectiveness of interventions that promote physical activity long-term, such as cycling and walking to and from work. Methods: This intervention focused on physically active commuting (cycling and walking) in middle-aged (30-60 years), abdominally obese (waist circumference >= 88 cm) women (n = 120), recruited by newspaper advertisement. The intervention group was a moderate-intensity programme with physician meetings, physical activity prescriptions, group counselling and bicycles. The control group was a low-intensity group support programme with pedometers. We used a randomized, controlled, 2-armed design with 18 months duration and intention-to-treat analysis (data collection 2005-2006). Treatment success was defined as bicycling >= 2 km/d (primary) or walking 10 000 steps per day (secondary). Results: At baseline, mean (s. d.) age was 48.2 years (7.4), waist circumference 103.8cm (7.8), walking 8471 steps per day (2646), bicycling 0 km per day. Attrition at 18 months was 10% for the intervention group and 25% in the control group (P = 0.03). The intervention group was more likely to achieve treatment success for cycling than controls: 38.7 vs 8.9% (odds ratio (OR) 7.8 (95% confidence interval = 4.0 to 15.0, P < 0.001)), but with no difference for compliance with the walking recommendation: 45.7 vs 39.3% (OR 1.2 (95% CI 0.7 to 2.0, P = 0.50)). Commuting by car and public transport were reduced by 34% (P < 0.01) and 37% (P < 0.001), respectively, with no differences between groups. Both groups attained similar waist reductions (-2.1 and -2.6 cm, P = 0.72). Conclusions: Abdominally obese women can increase PA long-term through moderate-intensity behavioural support aimed at changing commuting habits. International Journal of Obesity (2009) 33, 645-652; doi: 10.1038/ijo.2009.77; published online 5 May 2009
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| 5. |
- P, Nerfeldt, et al.
(author)
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Weight reduction improves nocturnal respiration in obese sleep apnoea patients- : A randomized controlled pilot study
- 2008
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In: Obesity Research and Clinical Practice. - : Elsevier BV. - 1871-403X .- 1878-0318.
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Journal article (peer-reviewed)abstract
- ObjectivesRandomized controlled pilot study of the effect of weight reduction on nocturnal respiratory parameters in obese patients with obstructive sleep apnoea syndrome (OSAS).MethodsTwenty consecutive obese male patients fulfilling OSAS criteria at Karolinska University Hospital were randomized into two groups. Intervention with an 8-week weight reduction programme consisting of a low-calorie diet, together with group meetings, was evaluated compared to expectancy alone for the control group, followed by a crossover. Follow-up at 3 months included anthropometrics and ambulant sleep apnoea recordings.ResultsEleven of twenty men completed the protocol. There were significant differences between the intervention group (n = 6) and the control group (n = 5) in changes of weight (p < 0.01) and oxygen desaturation index (ODI4) (p < 0.05). We also found a significant positive correlation in these 11 males after the crossover between their reduction in weight and their reduction in ODI4 (p < 0.05).ConclusionsThis pilot study indicates that weight reduction improves nocturnal respiration in obese OSAS patients after 3 months’ dietary treatment compared to expectancy.
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| 6. |
- P, Nerfeldt, et al.
(author)
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Weight reduction improves sleep, sleepiness and metabolic status in obese sleep apnoea patients.
- 2008
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In: Obesity Research and Clinical Practice. - : Elsevier BV. - 1871-403X .- 1878-0318. ; 2:4, s. 251-262
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Journal article (peer-reviewed)abstract
- MethodIn this prospective intervention study, 33 obese patients with obstructive sleep apnoea syndrome (OSAS) (24 men, 9 women) were consecutively enrolled for a weight reduction program at the Obesity Unit, Karolinska University Hospital. 23 of 33 patients used OSAS-device, 19 with Continuous Positive Airway Pressure and 4 with Mandibular Retaining Device. The patients were investigated with questionnaires, blood tests and ambulant nocturnal polysomnography before and after a 6-month program. Patients with OSAS-device slept without it during the sleep studies. The intervention consisted of 8 weeks low calorie diet and group meetings, followed by a day-care program of behaviour change support.Results27 of 33 patients (82%, 21 men and 6 women) completed the study. After the intervention there were highly significant decreases (p < 0.001) in Body Mass Index from mean(S.D.) 40(5) to 34(3), apnoea–hypopnoea index from 43(24) to 26(20) and Epworth Sleepiness Scale (ESS)-score from 9(4) to 6(4). Sleep quality (arousal index, sleep efficiency, percentage deep sleep) and metabolic status (blood pressure, blood glucose levels, lipidemia) were also significantly improved. There was a significant correlation between increased percentage deep sleep and reduced ESS-score. There were no differences due to gender or use/no use of OSAS-device.ConclusionThe results suggest that weight loss, induced by low calorie diet and behaviour change support, significantly improves nocturnal respiratory parameters, sleep quality, daytime sleepiness and metabolic status in obese OSAS patients after 6 months.
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