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1.	Grosso, G, et al. (author) Thrombin activatable fibrinolysis inhibitor (TAFI) - A possible link between coagulation and complement activation in the antiphospholipid syndrome (APS) 2017 In: Thrombosis research. - : Elsevier BV. - 1879-2472 .- 0049-3848. ; 158, s. 168-173 Journal article (peer-reviewed)
2.	Antovic, A, et al. (author) Thrombin activatable fibrinolysis inhibitor - TAFI as a possible link between coagulation and complement activation in patients with the antiphospholipid syndrome 2015 In: THROMBOSIS RESEARCH. - 0049-3848. ; 135, s. S69-S69 Conference paper (other academic/artistic)
3.	Mobarrez, F, et al. (author) Increased levels of microvesicles containing nuclear molecules and immunoglobulins in patients with systemic lupus erythematosus 2016 In: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. - 0300-9742. ; 45, s. 38-39 Conference paper (other academic/artistic)
4.	Mobarrez, F., et al. (author) The Expression Of Microparticles In The Blood Of Patients With Systemic Lupus Erythematosus (SLE) : Phenotypic Characterization And Clinical Associations 2016 In: Clinical and Experimental Rheumatology. - 0392-856X .- 1593-098X. ; 34:4, s. S70-S70 Journal article (peer-reviewed)
5.	Vikerfors, A, et al. (author) MICROPARTICLES IN 290 SLE PATIENTS AND MATCHED CONTROLS AND THEIR RELATIONSHIP TO VASCULAR DISEASE 2015 In: ANNALS OF THE RHEUMATIC DISEASES. - : BMJ. - 0003-4967 .- 1468-2060. ; 74, s. 798-798 Conference paper (other academic/artistic)
6.	Frodlund, Martina, et al. (author) Immunoglobulin A anti-phospholipid antibodies in Swedish cases of systemic lupus erythematosus : associations with disease phenotypes, vascular events and damage accrual 2018 In: Clinical and Experimental Immunology. - : WILEY. - 0009-9104 .- 1365-2249. ; 194:1, s. 27-38 Journal article (peer-reviewed)abstract Immunoglobulin (Ig) G- and IgM-class anti-cardiolipin antibodies (aCL) and lupus anti-coagulant (LA) are included in the 1997 update of the American College of Rheumatology (ACR-97) systemic lupus erythematosus (SLE) criteria. Despite limited evidence, IgA-aCL and IgA anti-(2)-glycoprotein-I (anti-(2)GPI) were included in the 2012 Systemic Lupus International Collaborating Clinics criteria. The present study aimed to evaluate IgG-/IgA-/IgM-aCL and anti-(2)GPI occurrence in relation to disease phenotype, smoking habits, pharmacotherapy, anti-phospholipid syndrome (APS) and organ damage among 526 Swedish SLE patients meeting ACR-97. Patients with rheumatoid arthritis (n=100), primary Sjogren's syndrome (n=50) and blood donors (n=507) served as controls. Anti-phospholipid antibodies (aPL) were analysed by fluoroenzyme-immunoassays detecting aCL/anti-(2)GPI. Seventy-six (14%) SLE cases fulfilled the Sydney APS-criteria, and 1 aCL/anti-(2)GPI isotype (IgG/IgA/IgM) occurred in 138 SLE patients (26%). Forty-five (9%) of the SLE cases had IgA-aCL, 20 of whom (4%) lacked IgG-/IgM-aCL. Seventy-four (14%) tested positive for IgA anti-(2)GPI, 34 (6%) being seronegative regarding IgG/IgM anti-(2)GPI. Six (1%) had APS manifestations but were seropositive regarding IgA-aCL and/or IgA anti-(2)GPI in the absence of IgG/IgM-aPL and LA. Positive LA and IgG-aPL tests were associated with most APS-related events and organ damage. Exclusive IgA anti-(2)GPI occurrence associated inversely with Caucasian ethnicity [odds ratio (OR)=021, 95% confidence interval (CI)=006-072) and photosensitivity (OR=019, 95% CI=005-072). Nephritis, smoking, LA-positivity and statin/corticosteroid-medication associated strongly with organ damage, whereas hydroxychloroquine-medication was protective. In conclusion, IgA-aPL is not rare in SLE (16%) and IgA-aPL analysis may have additional value among SLE cases with suspected APS testing negative for other isotypes of aPL and LA.
7.	Frodlund, M., et al. (author) Immunoglobulin A anti-phospholipid antibodies in Swedish cases with systemic lupus erythematosus : associations with disease phenotypes, vascular events, and damage accrual 2018 In: Scandinavian Journal of Rheumatology. - : TAYLOR & FRANCIS LTD. - 0300-9742 .- 1502-7732. ; 47, s. 48-48 Journal article (other academic/artistic)

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Result 1-7 of 7

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Type of publication: journal article (4); conference paper (3)

Type of content: other academic/artistic (4); peer-reviewed (3)

Author/Editor: Svenungsson, E (7); Vikerfors, A (7); Gunnarsson, I (4); Gustafsson, J (3); Wallen, H (3); Mobarrez, F (3); show more...; Zickert, A (3); Grosso, G (2); Adam, M (2); Rönnelid, Johan (2); Elvin, K (2); Antovic, A (2); Woodhams, B (2); Pisetsky, D (2); Larsson, Anders (1); Sjowall, C (1); Agren, A (1); Holmstrom, M (1); Dahlström, Örjan (1); Sjöwall, Christopher (1); Bremme, K (1); Skogh, Thomas (1); Kastbom, Alf (1); Bruzelius, M (1); Eelde, A (1); Wetterö, Jonas (1); Frodlund, Martina (1); Frodlund, M. (1); show less...

University: Karolinska Institutet (7); Uppsala University (3); Linköping University (1)

Language: English (7)

Research subject (UKÄ/SCB): Medical and Health Sciences (3)

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