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Search: WFRF:(Vissers M.) > (2010-2014)

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1.
  • Frisk Kockum, Anton, 1987, et al. (author)
  • Detailed modelling of the susceptibility of a thermally populated, strongly driven circuit-QED system
  • 2013
  • In: Journal of Physics B: Atomic, Molecular and Optical Physics. - : IOP Publishing. - 1361-6455 .- 0953-4075. ; 46:22
  • Journal article (peer-reviewed)abstract
    • We present measurements and modelling of the susceptibility of a 2D microstrip cavity coupled to a driven transmon qubit. We are able to fit the response of the cavity to a weak probe signal with high accuracy in the strong coupling, low detuning, i.e., non-dispersive, limit over a wide bandwidth. The observed spectrum is rich in multi-photon processes for the doubly dressed transmon. These features are well explained by including the higher transmon levels in the driven Jaynes-Cummings model and solving the full master equation to calculate the susceptibility of the cavity.
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2.
  • Helsmoortel, Celine, et al. (author)
  • A SWI/SNF-related autism syndrome caused by de novo mutations in ADNP
  • 2014
  • In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 46:4, s. 380-
  • Journal article (peer-reviewed)abstract
    • Despite the high heritability of autism spectrum disorders (ASD), characterized by persistent deficits in social communication and interaction and restricted, repetitive patterns of behavior, interests or activities(1), a genetic diagnosis can be established in only a minority of patients. Known genetic causes include chromosomal aberrations, such as the duplication of the 15q11-13 region, and monogenic causes, as in Rett and fragile- X syndromes. The genetic heterogeneity within ASD is striking, with even the most frequent causes responsible for only 1% of cases at the most. Even with the recent developments in nextgeneration sequencing, for the large majority of cases no molecular diagnosis can be established(2-7). Here, we report ten patients with ASD and other shared clinical characteristics, including intellectual disability and facial dysmorphisms caused by a mutation in ADNP, a transcription factor involved in the SWI/ SNF remodeling complex. We estimate this gene to be mutated in at least 0.17% of ASD cases, making it one of the most frequent ASD- associated genes known to date.
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  • Result 1-6 of 6

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