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- Tabar, L, et al.
(author)
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The Swedish two-county trial twenty years later - Updated mortality results and new insights from long-term follow-up
- 2000
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In: The Radiologic clinics of North America. - 0033-8389 .- 1557-8275. ; 38:4, s. 625-
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Journal article (peer-reviewed)abstract
- This article updates the results 20 years later of the Swedish Two-County Trial of mammographic screening for breast cancer. The result remains a substantial and significant 32% reduction in breast cancer mortality in association with an invitation to be screened. It is shown that the effect of screening can be ascribed to a shift in the prognostic character of the tumors diagnosed, that in turn can be used as a measure of the quality of a screening program. The results on prognosis also identify a group of small but high-risk tumors, with fundamental implications for diagnosis and treatment.
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- Thurfjell, M G, et al.
(author)
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Effect on sensitivity and specificity of mammography screening with or without comparison of old mammograms
- 2000
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In: Acta Radiologica. - : SAGE Publications. - 0284-1851 .- 1600-0455. ; 41:1, s. 52-56
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Journal article (peer-reviewed)abstract
- Purpose: To evaluate the effect of old mammograms on the specificity and sensitivity of radiologists in mammography screening. Material and Methods: One hundred and fifty sets of screening mammograms were examined by 3 experienced screeners twice: once without and once in comparison with older mammograms. The films came from a population-based screening done during the first half of 1994 and comprised all 35 cancers detected during screening in 1994, 12/24 interval cancers, 14/34 cancers detected in the following screening and 89 normal mammograms. Results: Without old mammograms, the screeners detected an average of 40.3 cancers (range 37-42), with a specificity of 87% (85-88%). With old mammograms, the screeners detected 37.7 cancers (range 34-42) with a specificity of 96% (94-99%). The change in detection rate was not significant. However, the increase in specificity was significant for each screener (p=0.0002-0.03). Conclusion: Mammography screening with old mammograms available for comparison decreased the false-positive recall rate. The effect on sensitivity, however, was unclear.
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