| 11. |
- Abdelzaher, T., et al.
(author)
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The aperiodic multiprocessor utilization bound for liquid tasks
- 2002
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In: 8th IEEE Real-Time and Embedded Technology and Applications Symposium, 2002. Proceedings. - 1545-3421. - 0769517390 ; , s. 173-184
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Conference paper (peer-reviewed)abstract
- Real-time scheduling theory has developed powerful tools for translating conditions on aggregate system utilization into per-task schedulability guarantees. The main breakthrough has been Liu and Layland's utilization bound for schedulability of periodic tasks. In 2001 this bound was generalized by Abdelzaher and Lu to the aperiodic task case. In this paper we further generalize the aperiodic bound to the case of multiprocessors, and present key new insights into schedulability, analysis of aperiodic tasks. We consider a special task model, called the liquid task model, representative of high-performance servers with aperiodic workloads, such as network routers, web servers, proxies, and real-time databases. For this model, we derive the optimal multiprocessor utilization bound, defined on a utilization-like metric we call "synthetic utilization". This bound allows developing constant-time admission control tests that provide utilization-based absolute delay, tees. We show that the real utilization of admitted tasks can be close to unity even when synthetic utilization is kept below the bound. Thus, our results lead to multiprocessor systems which combine constant-time admission control with high utilization while making no periodicity assumptions regarding the task arrival pattern.
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| 12. |
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| 13. |
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| 14. |
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| 15. |
- Al-Khalili, A, et al.
(author)
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Dissociative recombination cross section and branching ratios of protonated dimethyl disulfide and N-methylacetamide
- 2004
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In: Journal of Chemical Physics. - : AIP Publishing. - 0021-9606 .- 1089-7690. ; 121:12, s. 5700-5708
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Journal article (peer-reviewed)abstract
- Dimethyl disulfide (DMDS) and N-methylacetamide are two first choice model systems that represent the disulfide bridge bonding and the peptide bonding in proteins. These molecules are therefore suitable for investigation of the mechanisms involved when proteins fragment under electron capture dissociation (ECD). The dissociative recombination cross sections for both protonated DMDS and protonated N-methylacetamide were determined at electron energies ranging from 0.001 to 0.3 eV. Also, the branching ratios at 0 eV center-of-mass collision energy were determined. The present results give support for the indirect mechanism of ECD, where free hydrogen atoms produced in the initial fragmentation step induce further decomposition. We suggest that both indirect and direct dissociations play a role in ECD.
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| 16. |
- Amarger, V, et al.
(author)
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Comparative sequence analysis of the PRKAG3 region between human and pig : evolution of repetitive sequences and potential new exons
- 2003
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In: Cytogenetic and Genome Research. - : S. Karger AG. - 1424-8581 .- 1424-859X. ; 102:1-4, s. 163-172
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Journal article (peer-reviewed)abstract
- The PRKAG3 gene encodes the gamma3 chain of AMP-activated protein kinase (AMPK). A non-conservative missense mutation in the PRKAG3 gene causes a dominant phenotype involving abnormally high glycogen content in pig skeletal muscle. We have determined >126 kb (in 13 contigs) of porcine genomic sequence surrounding the PRKAG3 gene and the corresponding mouse region covering the gene. A comparison of these PRKAG3 sequences and the human sequence was conducted and used to predict evolutionarily conserved regions, including regulatory regions. A comparison of the human genomic sequence and a porcine BAC sequence containing the PRKAG3 gene, revealed a conserved organization and the presence of three additional genes, CYP27A1 (cytochrome P450, family 27, subfamily A, polypeptide 1), STK36 (Serine Threonine Kinase 36), and the homolog of the unidentified human mRNA KIAA0173. Interspersed repetitive elements constituted 51.4 and 38.6% of this genomic region in human and pig, respectively. We were able to reliably align 12.6 kb of orthologous repeats shared between pig and human and these showed an average sequence identity of 72.4%. Our analysis revealed that the human KIAA0173 gene harbors alternative 5' untranslated exons originating from repetitive elements. This provides an obvious example how transposable elements may affect gene evolution.
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| 17. |
- Andersson, Gerhard, et al.
(author)
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Förekomst av tinnitus i Sverige
- 2002
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In: Läkaresällskapets Rikstämma 27-29 november 2002. ; , s. 130-
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Conference paper (peer-reviewed)
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| 18. |
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| 19. |
- Andersson, Jenny, et al.
(author)
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Absence of the Lhcb1 and Lhcb2 proteins of the light-harvesting complex of photosystem II - effects on photosynthesis, grana stacking and fitness
- 2003
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In: The Plant Journal. - : Wiley. - 0960-7412 .- 1365-313X. ; 35:3, s. 350-361
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Journal article (peer-reviewed)abstract
- We have constructed Arabidopsis thaliana plants that are virtually devoid of the major light-harvesting complex, LHC II. This was accomplished by introducing the Lhcb2.1 coding region in the antisense orientation into the genome by Agrobacterium-mediated transformation. Lhcb1 and Lhcb2 were absent, while Lhcb3, a protein present in LHC II associated with photosystem (PS) II, was retained. Plants had a pale green appearance and showed reduced chlorophyll content and an elevated chlorophyll a/b ratio. The content of PS II reaction centres was unchanged on a leaf area basis, but there was evidence for increases in the relative levels of other light harvesting proteins, notably CP26, associated with PS II, and Lhca4, associated with PS I. Electron microscopy showed the presence of grana. Photosynthetic rates at saturating irradiance were the same in wild-type and antisense plants, but there was a 10-15% reduction in quantum yield that reflected the decrease in light absorption by the leaf. The antisense plants were not able to perform state transitions, and their capacity for non-photochemical quenching was reduced. There was no difference in growth between wild-type and antisense plants under controlled climate conditions, but the antisense plants performed worse compared to the wild type in the field, with decreases in seed production of up to 70%.
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