| 11. |
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Glänta
- 2021
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Editorial collection (pop. science, debate, etc.)
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| 12. |
- Hammarsten, Ola, et al.
(author)
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Clinical measurement of cellular DNA damage hypersensitivity in patients with DNA repair defects
- 2022
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In: Orphanet Journal of Rare Diseases. - : Springer Science and Business Media LLC. - 1750-1172. ; 17:1
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Journal article (peer-reviewed)abstract
- Background: DNA repair deficiency disorders are rare inherited diseases arising from pathogenic (disease-causing) variants in genes involved in DNA repair. There are no standardized diagnostic assays for the investigation of pathological significance of unknown variants in DNA repair genes. We hypothesized that our assays for measuring in vitro patient blood cell hypersensitivity to DNA-damaging agents can be used to establish the pathological significance of unknown variants in DNA repair genes. Six patients with variants in the DNA repair genes PRKDC (two siblings), DCLRE1C (two siblings), NBN, and MSH6 were included. Here, we used the cell division assay (CDA) and the gamma-H2AX assay, which were both developed and clinically validated by us, to measure patient cell hypersensitivity in response to ionizing radiation, mitomycin C, cytarabine and doxorubicin. Results: Radiation hypersensitivity was detected in the two patients with variants in the PRKDC gene (p < 0.0001 for both at 3.5 Gy), and the two patients with DCLRE1C variants (p < 0.0001 at 3.5 Gy for sibling 1 and p < 0.0001 at 1 Gy for sibling 2). The cells from the patients with the PRKDC variant were also deficient in removing gamma-H2AX (p < 0.001). The cells from the patient with variants in the NBN gene were hypersensitive to mitomycin C (p = 0.0008) and deficient in both induction and removal of gamma-H2AX in response to radiation. Conclusions: The combination of the CDA and the gamma-H2AX assay is useful in investigating the significance of unknown variants in some DNA repair genes.
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| 13. |
- Hansson, Anna, 1984-, et al.
(author)
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Biogas production in the industrial symbiosis context – facilitating collaboration through digitalization
- 2024
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In: 5THCESUST2024: 5TH SYMPOSIUM ON CIRCULAR ECONOMY AND SUSTAINABILITY.
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Conference paper (peer-reviewed)abstract
- Improving sustainability performance and adapting to circular economy principles in operational business strategies are becoming increasingly prioritized. In this pursuit, the concept of industrial symbiosis (IS) has become increasingly relevant. IS represents a collaborative approach where the interplay of material, residual waste, energy, and infrastructure exchanges aims to yield not only economic and environmental advantages for the participating companies but also substantial societal benefits by using resources more efficiently. Biogas production is such an example, it can reduce greenhouse gas emissions since it can produce heat and electricity, replace renewable fuel for vehicles, or be used as input material for industrial use. The digestate from biogas production can also be used as an effective agricultural fertilizer to replace chemical fertilizers which are produced using fossil energy.Digital tools and platforms in IS can be used to different extent depending on businesses levels of digital maturity (the extent to which businesses adapt to ongoing digital change and integrate digitalization). Digital tools and platforms hold a central role for developing various advantages in biogas-based IS, but since the digital maturity for IS focusing on biogas production is uncertain, the current efficiency obtained by tools and platforms is unknown. Therefore, through semi-structured interviews and study visits, this study assesses stakeholder collaboration and use of digital tools at five IS sites with biogas production in Sweden. It explores (i) current digital maturity and collaboration characteristics amongst established biogas-based IS, and (ii) needs amongst stakeholders for development of digital tools and platforms to promote digital maturity, monitoring, collaboration, and knowledge exchange in current and future IS structures.Preliminary results of the on-going study show that the use of digital tools varies depending on the character and size of resource flows that are included in the collaboration, and due to the internal digital maturity of the involved companies. In general, the use of digital tools for stakeholder interaction is on low or medium level, in which manual handling is required and little is automated. This complies with the sites being relatively small, and the number of stakeholders involved are relatively few. Moreover, the preliminary results show that the interest of future development of digital tools is found to be related to business development and expanded market opportunities through diversified raw material use, increased production, and new distribution channels. In addition, a demand of digital platforms for exchange of experience and competence supply has been identified.
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| 14. |
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| 15. |
- Johansson, Sven Anders, 1968-
(author)
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Den icke-metodiska uppmärksamheten. : Toril Mois Revolutionary of the Ordinary
- 2022
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In: Edda. Nordisk tidsskrift for litteraturforskning. - : Universitetsforlaget. - 0013-0818 .- 1500-1989. ; 109:1, s. 43-46
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Journal article (other academic/artistic)abstract
- Förmodligen har ingen bok påverkat skandinavisk litteraturvetenskap mer, under de senaste fem åren, än Toril Mois Revolution of the Ordinary: Literary Studies after Wittgenstein, Austin, and Cavell. Den statusen gör det angeläget att reflektera både över dess styrkor och eventuella brister. Varför är det en viktig bok? Och vilka invändningar väcker den, fyra år efter utgivningen? Det var också ungefär så uppdraget löd inför det seminarium som först föranledde den här texten: peka ut något positivt, något oklart och något negativt i Mois bok! Eftersom den är så innehållsrik, och eftersom den handlar om frågor som upptagit mig under lång tid, var svårigheten snarast att begränsa sig.
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| 16. |
- Johansson, Sven Anders, 1968-
(author)
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Dialektik
- 2020
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In: Glänta. - : Kulturföreningen Glänta. - 1104-5205. ; :1-2, s. 16-18
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Journal article (other academic/artistic)
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| 17. |
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| 18. |
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| 19. |
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| 20. |
- Johansson, Sven Anders, 1968-
(author)
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”Jag är bara här” : Humanvetenskaperna, klimataktivismen och apatin som möjlighet
- 2024
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In: K & K. - 0905-6998 .- 2246-2589. ; 52:137, s. 87-108
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Journal article (peer-reviewed)abstract
- The article takes as its starting point Leo Tolstoy’s character Pierre Bezukhov. His passive presence at the battle of Borodino, in Tolstoy’s War and Peace, is contrasted with today’s climate activism, exemplified by the Swedish human ecologist Andreas Malm. In his book How to Blow up a Pipeline, Malm argues that global warming forces scientists and scholars to become activists, and activists to turn to violence. This analysis, the article argues, is based on a simplistic notion of action (”one acts or one does not”) and a strong conviction of being right. If this certitude is problematic, it is also typical of our time. Where, then, does this tendency to simplify the complicated, and replace all uncertainty with sureness, come from? One answer is that activism requires determination, which in its turn presupposes access to the truth. Another explanation lies in the binary operations of the digital media we all rely upon. At the most basic level, these operations exclude all approximation, all nuances, all doubt: the options are one or zero. Against this background, it becomes crucial to defend a research practice that refrains from simplifications. In Sloterdijk, the article finds an argument for interrupting the affective impulses that reach us constantly. From Popper, it fetches an understanding of research as an event. Via Marx’s well-known formulation that philosophers must change the world, not just interpret it, the text then moves to Adorno’s defense of theoretical thinking. The question is, however, whether critical theory has any edge left. Has it not just become a part of the academic apparatus it once reacted against? The article finds an answer in Lyotard, and his idea of a theoretical apathy. This idea reminds a lot of the starting point of the article: Pierre Bezukhov’s comic but clear-sighted passivity on the battlefield.
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