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Träfflista för sökning "WFRF:(Yoon J) srt2:(2015-2019)"

Search: WFRF:(Yoon J) > (2015-2019)

  • Result 41-50 of 118
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41.
  • Ahdida, C., et al. (author)
  • The experimental facility for the Search for Hidden Particles at the CERN SPS
  • 2019
  • In: Journal of Instrumentation. - : Institute of Physics Publishing (IOPP). - 1748-0221. ; 14
  • Journal article (peer-reviewed)abstract
    • The Search for Hidden Particles (SHiP) Collaboration has shown that the CERN SPS accelerator with its 400 GeV/c proton beam offers a unique opportunity to explore the Hidden Sector [1-3]. The proposed experiment is an intensity frontier experiment which is capable of searching for hidden particles through both visible decays and through scattering signatures from recoil of electrons or nuclei. The high-intensity experimental facility developed by the SHiP Collaboration is based on a number of key features and developments which provide the possibility of probing a large part of the parameter space for a wide range of models with light long-lived super-weakly interacting particles with masses up to O(10) GeV/c(2) in an environment of extremely clean background conditions. This paper describes the proposal for the experimental facility together with the most important feasibility studies. The paper focuses on the challenging new ideas behind the beam extraction and beam delivery, the proton beam dump, and the suppression of beam-induced background.
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  • Lawrenson, Kate, et al. (author)
  • Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus
  • 2016
  • In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 7
  • Journal article (peer-reviewed)abstract
    • A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 mutation carriers and 73,444 controls and identify 13 candidate causal SNPs associated with serous OC (P=9.2 × 10-20), ER-negative BC (P=1.1 × 10-13), BRCA1-associated BC (P=7.7 × 10-16) and triple negative BC (P-diff=2 × 10-5). Genotype-gene expression associations are identified for candidate target genes ANKLE1 (P=2 × 10-3) and ABHD8 (P<2 × 10-3). Chromosome conformation capture identifies interactions between four candidate SNPs and ABHD8, and luciferase assays indicate six risk alleles increased transactivation of the ADHD8 promoter. Targeted deletion of a region containing risk SNP rs56069439 in a putative enhancer induces ANKLE1 downregulation; and mRNA stability assays indicate functional effects for an ANKLE1 3′-UTR SNP. Altogether, these data suggest that multiple SNPs at 19p13 regulate ABHD8 and perhaps ANKLE1 expression, and indicate common mechanisms underlying breast and ovarian cancer risk.
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  • Result 41-50 of 118
Type of publication
journal article (115)
research review (3)
Type of content
peer-reviewed (116)
other academic/artistic (2)
Author/Editor
Kim, D. (23)
Venketasubramanian, ... (23)
Gupta, R. (22)
Larsson, Anders (22)
Malekzadeh, R (21)
Vos, T (21)
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Yonemoto, N (21)
Dandona, L (20)
Dandona, R (20)
Farzadfar, F (20)
Koyanagi, A (20)
Monasta, L (20)
Moradi-Lakeh, M (20)
Sartorius, B (20)
Shiri, R (20)
Topor-Madry, R (20)
Werdecker, A (20)
Weiderpass, E (19)
Bedi, N (19)
Bikbov, B (19)
Deribe, K (19)
Faro, A (19)
Fischer, F (19)
Karch, A (19)
Kinfu, Y (19)
Lalloo, R (19)
Majeed, A (19)
Meretoja, A (19)
Naghavi, M (19)
Nangia, V (19)
Remuzzi, G (19)
Roshandel, G (19)
Abd-Allah, F (18)
Aboyans, V (18)
Alam, K (18)
Alla, F (18)
Catala-Lopez, F (18)
Das Neves, J (18)
Esteghamati, A (18)
Hamidi, S (18)
Jeemon, P (18)
Leigh, J (18)
Lozano, R (18)
Ortiz, A (18)
Perico, N (18)
Ronfani, L (18)
Sharma, R (18)
Yano, Y (18)
Yip, P (18)
Zodpey, S (18)
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University
Karolinska Institutet (74)
Uppsala University (57)
Lund University (51)
Högskolan Dalarna (25)
University of Gothenburg (23)
Stockholm University (19)
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Umeå University (13)
Chalmers University of Technology (12)
Mid Sweden University (7)
Örebro University (6)
Royal Institute of Technology (5)
Södertörn University (5)
Jönköping University (3)
University of Skövde (3)
Linköping University (2)
Swedish University of Agricultural Sciences (2)
Halmstad University (1)
Linnaeus University (1)
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Language
English (118)
Research subject (UKÄ/SCB)
Medical and Health Sciences (70)
Natural sciences (39)
Social Sciences (5)
Engineering and Technology (3)
Agricultural Sciences (1)

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