| 51. |
- Von Proschwitz, Ted
(author)
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Miljöövervakningsstudierav landlevande snäckor på Gotland
- 1998
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Reports (other academic/artistic)abstract
- På uppdrag av Länsstyrelsen i Gotlands län genomfördes under perioden 21-31 oktober 1997 återinventeringar av molluskfaunan på 56 gotländska lokaler Som tidigare (1917-1953) undersökts i samband med Göteborgs Naturhisoriska Museums markfaunainventering. Återinventeringarna ingår i Länsstyrelsens program för övervakning av miljön på Gotland. Undersökningens målsättning var att:1. Återundersöka alla genom markfaunainventeringen kända förekomster i länet för tio särskilt utvalda hotade eller sällsynta landsnäcksarter för att fastställa om dessa kvarlever på lokalerna och att om möjligt bedöma kvarvarande populationers status.2. Om möjligt spåra anledningen till arternas eventuella tillbakagång eller försvinnande.3. Med ledning av resultaten från ovanstående ge rekommendationer om åtgärder för att säkra arternas fortlevnad på Gotland.
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| 52. |
- Kyrönviita, Jonas, 1988, et al.
(author)
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Achieving Blue Growth Post-Weser : a Study of Aquaculture Regulation in the Nordic Region
- 2021
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In: Journal for European Environmental & Planning Law. - : Brill Nijhoff. - 1613-7272 .- 1876-0104. ; 18:3, s. 256-274
-
Journal article (peer-reviewed)abstract
- This article explores how the conflict between the interests of protecting water quality in the coastal waters of the Baltic Sea from nutrient emissions on one hand, and supporting blue growth in the aquaculture sector on the other, has played out in the Nordic legal systems and industry practice. It does so by reviewing the legal and industrial developments in Sweden, Denmark, Finland and the Åland Islands with a focus on interpretation and application of the common EU regulatory framework, mainly the Water Framework Directive and the ecj Weser ruling, and the response from the aquaculture sector. The study shows that the four studied jurisdictions have taken disparate regulatory approaches in balancing ecological status of waters and blue growth. As a consequence of these legal developments, the aquaculture industry faces difficulty in attaining required permits for their operations in all four jurisdictions and significant uncertainty on how to develop the sector to meet the set growth objectives has arisen.
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| 53. |
- Leinsalu, Mall, 1958-, et al.
(author)
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Macroeconomic changes and trends in dental care utilization in Estonia and Lithuania in 2004-2012 : a repeated cross-sectional study
- 2018
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In: BMC Oral Health. - : BioMed Central. - 1472-6831 .- 1472-6831. ; 18:1
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Journal article (peer-reviewed)abstract
- BACKGROUND: The aim of this study was to assess trends and inequalities in dental care utilization in Estonia and Lithuania in relation to large-scale macroeconomic changes in 2004-2012.METHODS: Data on 22,784 individuals in the 20-64 age group were retrieved from nationally representative cross-sectional surveys in 2004, 2006, 2008, 2010 and 2012. Age- and sex-standardized prevalence estimates of past 12-month dental visits were calculated for each study year, stratified by gender, age group, ethnicity, educational level and economic activity. Multivariable logistic regression analysis was used to assess the independent effect of study year and socioeconomic status on dental visits.RESULTS: The age- and sex-standardized prevalence of dental visits in the past 12 months was 46-52% in Estonia and 61-67% in Lithuania. In 2004-2008, the prevalence of dental visits increased by 5.9 percentage points in both countries and fell in 2008-2010 by 3.8 percentage points in Estonia and 4.6 percentage points in Lithuania. In both countries the prevalence of dental care utilization had increased slightly by 2012, although the increase was statistically insignificant. Results from a logistic regression analysis showed that these differences between study years were not explained by differences in socioeconomic status or oral health conditions. Women, the main ethnic group (only in Estonia), and higher educated and employed persons had significantly higher odds of dental visits in both countries, but the odds were lower for 50-64 year olds in Lithuania.CONCLUSIONS: In European Union countries with lower national wealth, the use of dental services is sensitive to macroeconomic changes regardless of the extent of public coverage, at the same time, higher public coverage may not relate to lower inequalities in dental care use.
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| 54. |
- Foran, Susan
(author)
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Medieval Life-Writing
- 2023
-
Conference paper (other academic/artistic)abstract
- Medieval biography or life-writing is often considered within frameworks established by classical and modern biography. This session discusses medieval life-writing traditions within their literary entanglements. How is the individual life presented, and memorialised, in relation to social, political, intellectual or religious institutions, or communities? Is biography defined by an emphasis on the individual, and how far is this a focus on the self, identity, and emotion? How are tensions negotiated through rhetoric, convention, and style? What narrative models and historiographical sources provided inspiration? How are stories disseminated through transnational intellectual communities and martial networks? Sources include royal and chivalric biographies, hagiographies, obituaries, autobiographies, found alone or within chronicles, histories, and romance.
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| 55. |
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| 56. |
- Sturesson, Marine, 1959-, et al.
(author)
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Healthcare encounters and return to work : a qualitative study on sick-listed patients' experiences
- 2014
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In: Primary Health Care Research and Development. - : Cambridge University Press. - 1463-4236 .- 1477-1128. ; 15:4, s. 464-475
-
Journal article (peer-reviewed)abstract
- BACKGROUND: Sickness absence is a complex phenomenon affected by aspects other than disease. One important factor that can affect sick leave is the individual's experience of healthcare encounters. It is therefore essential to consider the quality of the encounter with health professionals and its impact on the patient's rehabilitation and return to work.AIM: The aim was to explore how sick-listed patients in Sweden perceive their contact with healthcare professionals in primary healthcare and to analyse what they view as crucial components for returning to work.METHODS: A qualitative approach was used. Data were collected by semi-structured telephonic interviews with patients who were or had been on sick leave. The transcribed interview text was analysed according to qualitative content analysis.FINDINGS: The analysis revealed two themes that highlight important areas for persons on sick leave in their healthcare encounters. The theme 'Trust in the relationship' contains categories describing the patients' feelings of participation, and of being believed, confirmed, and listened to, and also dedication on the part of healthcare providers. Healthcare encounters that were characterised by professionalism, knowledge, continuity, and a holistic approach seemed to create trust. The theme 'Structure and balance' contains the participants' views on important factors that could support the return-to-work process. All participants stated the importance of follow-up and a plan for rehabilitation. Sick leave itself can make a person passive, and participants in this study asked for support to balance activity, exercise, and work demands, which could facilitate their return to work.CONCLUSION: Healthcare professionals can facilitate sick-listed persons' rehabilitation back to work by providing a clear structure in the process and support in occupational balance. The healthcare encounters must build on a mutual trust.
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| 57. |
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| 58. |
- Hochman, A., et al.
(author)
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Dynamics and predictability of cold spells over the Eastern Mediterranean
- 2022
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In: Climate Dynamics. - : Springer Science and Business Media LLC. - 0930-7575 .- 1432-0894. ; 58:7-8, s. 2047-2064
-
Journal article (peer-reviewed)abstract
- The accurate prediction of extreme weather events is an important and challenging task, and has typically relied on numerical simulations of the atmosphere. Here, we combine insights from numerical forecasts with recent developments in dynamical systems theory, which describe atmospheric states in terms of their persistence (θ−1) and local dimension (d), and inform on how the atmosphere evolves to and from a given state of interest. These metrics are intuitively linked to the intrinsic predictability of the atmosphere: a highly persistent, low-dimensional state will be more predictable than a low-persistence, high-dimensional one. We argue that θ−1 and d, derived from reanalysis sea level pressure (SLP) and geopotential height (Z500) fields, can provide complementary predictive information for mid-latitude extreme weather events. Specifically, signatures of regional extreme weather events might be reflected in the dynamical systems metrics, even when the actual extreme is not well-simulated in numerical forecasting systems. We focus on cold spells in the Eastern Mediterranean, and particularly those associated with snow cover in Jerusalem. These rare events are systematically associated with Cyprus Lows, which are the dominant rain-bearing weather system in the region. In our analysis, we compare the ‘cold spell Cyprus Lows’ to other ‘regular’ Cyprus Low days. Significant differences are found between cold spells and ‘regular’ Cyprus Lows from a dynamical systems perspective. When considering SLP, the intrinsic predictability of cold spells is lowest hours before the onset of snow. We find that the cyclone’s location, depth and magnitude of air-sea fluxes play an important role in determining its intrinsic predictability. The dynamical systems metrics computed on Z500 display a different temporal evolution to their SLP counterparts, highlighting the different characteristics of the atmospheric flow at the different levels. We conclude that the dynamical systems approach, although sometimes challenging to interpret, can complement conventional numerical forecasts and forecast skill measures, such as model spread and absolute error. This methodology outlines an important avenue for future research, which can potentially be fruitfully applied to other regions and other types of weather extremes.
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| 59. |
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| 60. |
- FitzGerald, Edward, et al.
(author)
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Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors
- 2024
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In: SLAS Discovery. - : Elsevier. - 2472-5560 .- 2472-5552. ; :1, s. 40-51
-
Journal article (peer-reviewed)abstract
- Surface plasmon resonance (SPR) biosensor methods are ideally suited for fragment-based lead discovery. However, generally applicable experimental procedures and detailed protocols are lacking, especially for structurally or physico-chemically challenging targets or when tool compounds are not available. Success depends on accounting for the features of both the target and the chemical library, purposely designing screening experiments for identification and validation of hits with desired specificity and mode-of-action, and availability of orthogonal methods capable of confirming fragment hits. The range of targets and libraries amenable to an SPR biosensor-based approach for identifying hits is considerably expanded by adopting multiplexed strategies, using multiple complementary surfaces or experimental conditions. Here we illustrate principles and multiplexed approaches for using flow-based SPR biosensor systems for screening fragment libraries of different sizes (90 and 1056 compounds) against a selection of challenging targets. It shows strategies for the identification of fragments interacting with 1) large and structurally dynamic targets, represented by acetyl choline binding protein (AChBP), a Cys-loop receptor ligand gated ion channel homologue, 2) targets in multi protein complexes, represented by lysine demethylase 1 and a corepressor (LSD1/CoREST), 3) structurally variable or unstable targets, represented by farnesyl pyrophosphate synthase (FPPS), 4) targets containing intrinsically disordered regions, represented by protein tyrosine phosphatase 1B (PTP1B), and 5) aggregation-prone proteins, represented by an engineered form of human tau (tau K18M). Practical considerations and procedures accounting for the characteristics of the proteins and libraries, and that increase robustness, sensitivity, throughput and versatility are highlighted. The study shows that the challenges for addressing these types of targets is not identification of potentially useful fragments per se, but establishing methods for their validation and evolution into leads.
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