↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "L773:1545 9993 srt2:(1995-1999)"

Search: L773:1545 9993 > (1995-1999)

Result 1-4 of 4

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Berglund, H, et al. (author) Solution structure of the ribosomal RNA binding protein S15 from Thermus thermophilus 1997 In: Nature structural biology. - : Springer Science and Business Media LLC. - 1072-8368 .- 1545-9993 .- 1545-9985. ; 4:1, s. 20-23 Journal article (other academic/artistic)
2.	HARD, T, et al. (author) Solution structure of a mammalian PCB-binding protein in complex with a PCB 1995 In: Nature structural biology. - : Springer Science and Business Media LLC. - 1072-8368 .- 1545-9993 .- 1545-9985. ; 2:11, s. 983-989 Journal article (peer-reviewed)
3.	Larsson, Gunilla, et al. (author) Crystal structure of the Escherichia coli dUTPase in complex with a substrate analogue (dUDP) 1996 In: Nature Structural & Molecular Biology. - : Springer Science and Business Media LLC. - 1545-9985 .- 1545-9993. ; 3:6, s. 532-538 Journal article (peer-reviewed)abstract We have determined the structure of the homotrimeric dUTPase from Escherichia coli, complexed with an inhibitor and substrate analogue, dUDP. Three molecules of dUDP are found symmetrically bound per trimer, each in a shallow cleft between adjacent subunits, interacting with evolutionary conserved residues. The interactions of the uracil ring and the deoxypentose with the protein are consistent with the high specificity of the enzyme with respect to these groups. The positions of the two phosphate groups and adjacent water molecules are discussed in relation to the mechanism and kinetics of catalysis. The role that dUTPase plays in DNA metabolism makes the enzyme a potential target for chemotherapeutic drugs: the results presented here will aid in the design and development of inhibitory compounds.
4.	Otting, G, et al. (author) NMR identification of hydrophobic cavities with low water occupancies in protein structures using small gas molecules 1997 In: Nature structural biology. - : Springer Science and Business Media LLC. - 1072-8368 .- 1545-9993 .- 1545-9985. ; 4:5, s. 396-404 Journal article (peer-reviewed)

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-4 of 4

Refine your search

Type of publication: journal article (4)

Type of content: peer-reviewed (3); other academic/artistic (1)

Author/Editor: Hard, T (2); Frey, U (1); Larsson, C (1); Lund, J. (1); Svensson, L. Anders (1); Gustafsson, JA (1); show more...; Garber, M (1); Berglund, H (1); Otting, G (1); Liepinsh, E (1); Barnes, HJ (1); Rak, A (1); Serganov, A (1); Nyman, Per-Olof (1); Larsson, Gunilla (1); Halle, B (1); show less...

University: Karolinska Institutet (3); Lund University (1)

Language: English (4)

Research subject (UKÄ/SCB): Natural sciences (1)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view