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- Helgadottir, Anna, et al.
(author)
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The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm
- 2008
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In: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 40:2, s. 217-224
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Journal article (peer-reviewed)abstract
- Recently, two common sequence variants on 9p21, tagged by rs10757278-G and rs10811661-T, were reported to be associated with coronary artery disease (CAD)(1-4) and type 2 diabetes (T2D)(5-7), respectively. We proceeded to further investigate the contributions of these variants to arterial diseases and T2D. Here we report that rs10757278-G is associated with, in addition to CAD, abdominal aortic aneurysm (AAA; odds ratio (OR) 1.31, P = 1.2 x 10(-12)) and intracranial aneurysm (OR = 1.29, P = 2.5 x 10(-6)), but not with T2D. This variant is the first to be described that affects the risk of AAA and intracranial aneurysm in many populations. The association of rs10811661-T to T2D replicates in our samples, but the variant does not associate with any of the five arterial diseases examined. These findings extend our insight into the role of the sequence variant tagged by rs10757278-G and show that it is not confined to atherosclerotic diseases.
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- Collier, A. B., et al.
(author)
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Correlation between global lightning and whistlers observed at Tihany, Hungary
- 2009
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In: Journal of Geophysical Research. - 0148-0227 .- 2156-2202. ; 114, s. A07210-
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Journal article (peer-reviewed)abstract
- Although the generation and propagation mechanisms for whistlers are fairly well understood, the location and extent of the lightning source region for the whistlers observed at a given station are currently unknown. The correlation of whistler observations against global lightning data allows an estimate of the size and position of the source region. For whistlers detected at Tihany, Hungary, an area of positive correlation with radius of similar to 1000 km was found to be centered on the conjugate point. Although the maximal sample correlation coefficient was relatively low, r = 0.065, it has a high statistical significance, indicating that it is extremely improbable that the whistlers and lightning in this region are actually uncorrelated. Other smaller areas of positive correlation were found further afield in South America and the Maritime Continent. Lightning in the northern hemisphere displayed a negative correlation with whistlers at Tihany.
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- Oster, J., et al.
(author)
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Spatial correlation between lightning strikes and whistler observations from Tihany, Hungary
- 2009
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In: South African Journal of Science. - : Academy of Science of South Africa. - 0038-2353 .- 1996-7489. ; 105:5-6, s. 234-237
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Journal article (peer-reviewed)abstract
- A whistler is a very low frequency (VLF) phenomenon that acquires its characteristics from dispersive propagation in the magnetosphere. Whistlers are derived from the intense VLF radiation produced in lightning strikes, which can travel great distances within the Earth-ionosphere waveguide (EIWG) before penetrating the ionosphere, and exciting a duct. Field-aligned ducts of enhanced plasma density guide the propagation from one hemisphere to the other. The location of the duct, relative to the strike that causes the whistler, is unknown. Whistler time series from Tihany, Hungary, have been cross-correlated with lightning data obtained from the World Wide Lightning Location Network (WWLLN). The results show that whistlers observed at Tihany originate mainly from lightning strikes in an area with a radius of approximately 1 000 km surrounding the magnetic conjugate point in the Indian Ocean just east of East London, South Africa. A clear diurnal distinction was seen in that the correlation is maximised when the whistler station and the source region are in darkness. This is believed to relate to the diurnal variation of the ionosphere, which becomes more transparent to VLF waves at night.
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- Sundberg, K. Å. T., et al.
(author)
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Magnetic field oscillations at SANAE IV related to sudden increases in solar wind dynamic pressure
- 2005
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In: South African Journal of Science. - 0038-2353 .- 1996-7489. ; 101:12-nov, s. 539-543
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Journal article (peer-reviewed)abstract
- The magnetospheric response at times when sudden increases in the solar wind dynamic pressure cause terrestrial magnetic storms has been studied with data from the pulsation magnetometer at the South African Antarctic research base, SANAE IV. For solar wind events that lead to a sudden increase in the terrestrial magnetic field at Hermanus and Kakioka, related pulsations were found in the SANAE IV data. We studied seven solar wind events of special interest between 19 February 2003 and 18 February 2004. The events can be divided into two main pulsation groups: one group had a well-defined frequency and a duration of about 15 minutes, whereas the other had a less well-defined frequency content, longer duration and exhibited large amplitude fluctuations. The analysis confirms the conclusion that the measured response time of the magnetosphere to disturbances in the solar wind is broadly consistent with the propagation speed of magneto-hydrodynamic waves driven by solar wind dynamic pressure.
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