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Träfflista för sökning "WFRF:(Compston A) srt2:(2002-2004)"

Search: WFRF:(Compston A) > (2002-2004)

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1.	Harbo, H.F., et al. (author) Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis 2004 In: TISSUE ANTIGENS. - : Wiley. - 0001-2815 .- 1399-0039. ; 63:3, s. 237-247 Journal article (peer-reviewed)
2.	Akesson, E, et al. (author) A genome-wide screen for linkage in Nordic sib-pairs with multiple sclerosis 2002 In: Genes and Immunity. - : Springer Science and Business Media LLC. - 1476-5470 .- 1466-4879. ; 3:5, s. 279-285 Journal article (peer-reviewed)abstract Genetic factors influence susceptibility to multiple sclerosis but the responsible genes remain largely undefined, association with MHC class II alleles being the only established genetic feature of the disease. The Nordic countries have a high prevalence of multiple sclerosis, and to further explore the genetic background of the disease, we have carried out a genome-wide screen for linkage in 136 sibling-pairs with multiple sclerosis from Denmark, Finland, Norway and Sweden by typing 399 microsatellite markers. Seventeen regions where the lod score exceeds the nominal 5% significance threshold (0.7) were identified-1q11-24, 2q24-32, 3p26.3, 3q21.1, 4q12, 6p25.3, 6p21-22, 6q21, 9q34.3, 10p15, 10p12-13, 11p15.5, 12q21.3, 16p13.3, 17q25.3, 22q12-13 and Xp22.3. Although none of these regions reaches the level of genome-wide significance, the number observed exceeds the 10 that would be expected by chance alone. Our results significantly add to the growing body of linkage data relating to multiple sclerosis.
3.	Harbo, HF, et al. (author) Two genome-wide linkage disequilibrium screens in Scandinavian multiple sclerosis patients 2003 In: Journal of Neuroimmunology. - : Elsevier BV. - 1872-8421 .- 0165-5728. ; 143:1-2, s. 101-106 Journal article (peer-reviewed)abstract We report the first two genome-wide screens for linkage disequilibrium between putative multiple sclerosis (MS) susceptibility genes and genetic markers performed in the genetically homogenous Scandinavian population, using 6000 microsatellite markers and DNA pools of approximately 200 MS cases and 200 controls in each screen. Usable data were achieved from the same 3331 markers in both screens. Nine markers from eight genomic regions (1p33, 3q13, 6p21, 6q14, 7p22, 9p21, 9q21 and Xq22) were identified as potentially associated with MS in both screens. (C) 2003 Elsevier B.V. All rights reserved.
4.	Akesson, E, et al. (author) Refining the linkage analysis on chromosome 10 in 449 sib-pairs with multiple sclerosis 2003 In: Journal of neuroimmunology. - : Elsevier BV. - 0165-5728. ; 143:1-2, s. 31-38 Journal article (peer-reviewed)
5.	Lindvall, Olle, et al. (author) Restoring structure and function in the nigrostriatal system in Parkinson's disease 2002 In: Brain Disease: therapeutic strategies and repair. - 1841840408 - 9781841840406 ; , s. 275-282 Book chapter (other academic/artistic)

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Type of publication: journal article (4); book chapter (1)

Type of content: peer-reviewed (4); other academic/artistic (1)

Author/Editor: Oturai, A (4); Compston, A (4); Sawcer, S (4); Hillert, J (3); Akesson, E (3); Harbo, HF (3); show more...; Sandberg Wollheim, M ... (3); Spurkland, A (3); Svejgaard, A (3); Andersen, O (2); Fredrikson, S (2); Sorensen, PS (2); Laaksonen, M (2); Myhr, KM (2); Ryder, LP (2); Vartdal, F (2); Harbo, H. F. (1); Miller, A (1); Edland, A (1); Hagell, Peter (1); Lindvall, Olle (1); Berg, J (1); Nyland, HI (1); Holmans, P (1); Coraddu, F (1); Marrosu, MG (1); Massacesi, L (1); Hensiek, A (1); Trojano, M (1); Momigliano-Richiardi ... (1); Cocco, E (1); Murru, R (1); Hilbert, J (1); Lie, B. A. (1); Mellgren, S.I. (1); Myhr, K.-M. (1); Andersen, Ole (1); Said, G (1); Celius, EG (1); Datta, P (1); Setakis, E (1); Lorentzen, A. R. (1); Abramsky, O (1); Nyland, H (1); Modin, H. (1); Celius, E.G. (1); Dai, K.-Z. (1); Ryder, L.P. (1); S? ?rensen, P.S. (1); Compston, DAS (1); show less...

University: Lund University (4); Karolinska Institutet (4); University of Gothenburg (1)

Language: English (5)

Research subject (UKÄ/SCB): Medical and Health Sciences (4)

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