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Search: WFRF:(Helminen M)

  • Result 1-25 of 33
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1.
  • Aad, G., et al. (author)
  • 2013
  • In: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; :6
  • Journal article (peer-reviewed)
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  • Slimani, Melki, et al. (author)
  • The political dimension in environmental education curricula : Towards an integrative conceptual and analytical framework
  • 2021
  • In: Environmental Education Research. - : Informa UK Limited. - 1350-4622 .- 1469-5871. ; 27:3, s. 354-365
  • Journal article (peer-reviewed)abstract
    • The risk of neutralizing the political dimension in environmental education through the depoliticization of its thematic objects, its intended learning, and its educational purposes, is a curricular phenomenon identified by recent research in the field. The aim of this article is to develop a conceptual and analytical framework to identify clarification of the political dimension. The framework on the political dimension as part of environmental education provides political learning entry that help to avoid the vanishing of this dimension. Nevertheless, this is not without themes and cannot be decoupled from its educational aims. Therefore, establishing a conceptual and analytical framework considering environmental themes, political learning and educational purposes together can effectively support the curricular construction of environmental education’s political dimension. Thus, we define six environmental issue meta-themes by politicization and depoliticization trends that cross them; draw on environmental and political education research to identify political learning components in an environmental education context; and discuss linking political learning to possible educational purposes. We believe that within the dialectic of politicization/depoliticization that crosses the thematic subjects, learning and purposes of environmental education’s political dimension, the path leading to the democratic subjectification of learners guarantees its non-neutralization.
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  • Lorenz, Martin, et al. (author)
  • Relationship between condensed tannin structures and their ability to precipitate feed proteins in the rumen
  • 2014
  • In: Journal of the Science of Food and Agriculture. - : Wiley. - 1097-0010 .- 0022-5142. ; 94:5, s. 963-968
  • Journal article (peer-reviewed)abstract
    • BACKGROUND Tannins can bind to and precipitate protein by forming insoluble complexes resistant to fermentation and with a positive effect on protein utilisation by ruminants. Three protein types, Rubisco, rapeseed protein and bovine serum albumin (a single high-molecular weight protein), were used to test the effects of increasing concentrations of structurally different condensed tannins on protein solubility/precipitation. RESULTS Protein type (PT) influenced solubility after addition of condensed tannins (P < 0.001) in the order: Rubisco < rapeseed < BSA (P < 0.05). The type of condensed tannin (CT) affected protein solubility (P = 0.001) with a CT x PT interaction (P = 0.001). Mean degree of polymerisation, proportions of cis- versus trans-flavanol subunits or prodelphinidins versus procyanidins among CTs could not explain precipitation capacities. Increasing tannin concentration decreased protein solubility (P < 0.001) with a PT x CT concentration interaction. The proportion of low-molecular weight rapeseed proteins remaining in solution increased with CT concentration but not with Rubisco. CONCLUSIONS Results of this study suggest that PT and CT type are both of importance for protein precipitation but that the CT structures investigated did not allow identification of parameters that contribute most to precipitation. It is possible that the three-dimensional structures of tannins and proteins may be more important factors in tannin-protein interactions. (c) 2013 Society of Chemical Industry
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  • Kelhoffer, James Anthony, Professor i Nya testamentets exegetik, 1970- (author)
  • Second Clement
  • 2019. - 1
  • In: The Reception of Jesus in the First Three Centuries. - London : Bloomsbury Academic. - 9780567000194 ; , s. 513-530
  • Book chapter (peer-reviewed)abstract
    • Second Clement is a noteworthy early witness to the reception and creative interpretation of Jesus’s sayings, as compared with sayings preserved in the Gospels of Matthew, Luke, and Thomas. An unusual feature of its Christology is that, aside from “saving” believers, Christ is not said to play any role in their lives prior to the final judgment – for example, in guiding or protecting them.
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  • Haapakangas, Juho, et al. (author)
  • Coke Reactivity in Simulated Blast Furnace Shaft Conditions
  • 2016
  • In: Metallurgical and materials transactions. B, process metallurgy and materials processing science. - : Springer Science and Business Media LLC. - 1073-5615 .- 1543-1916. ; 47:4, s. 2357-2370
  • Journal article (peer-reviewed)abstract
    • Despite the fact that H2 and H2O are always present in the gas atmosphere of a blast furnace shaft, their role in the solution-loss reactions of coke has not been thoroughly examined. This study focuses on how H2 and H2O affect the reaction behavior and whether a strong correlation can be found between reactivity in the conditions of the CRI test (Coke Reactivity Index) and various simulated blast furnace shaft gas atmospheres. Partial replacement of CO/CO2 with H2/H2O was found to significantly increase the reactivity of all seven coke grades at 1373 K (1100 °C). H2 and H2O, however, did not have a significant effect on the threshold temperature of gasification. The reactivity increasing effect was found to be temperature dependent and clearly at its highest at 1373 K (1100 °C). Mathematical models were used to calculate activation energies for the gasification, which were notably lower for H2O gasification compared to CO2 indicating the higher reactivity of H2O. The reactivity results in gas atmospheres with CO2 as the sole gasifying component did not directly correlate with reactivity results in gases also including H2O, which suggests that the widely used CRI test is not entirely accurate for estimating coke reactivity in the blast furnace.
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  • Kaur, Upinder, et al. (author)
  • Reactive Oxygen Species, Redox Signaling and Neuroinflammation in Alzheimers Disease: The NF-kappa B Connection
  • 2015
  • In: Current Topics in Medicinal Chemistry. - : BENTHAM SCIENCE PUBL LTD. - 1568-0266 .- 1873-4294. ; 15:5, s. 446-457
  • Research review (peer-reviewed)abstract
    • Oxidative stress and inflammatory response are important elements of Alzheimers disease (AD) pathogenesis, but the role of redox signaling cascade and its cross-talk with inflammatory mediators have not been elucidated in details in this disorder. The review summarizes the facts about redox-signaling cascade in the cells operating through an array of kinases, phosphatases and transcription factors and their downstream components. The biology of NF-kappa B and its activation by reactive oxygen species (ROS) and proinflammatory cytokines in the pathogenesis of AD have been specially highlighted citing evidence both from post-mortem studies in AD brain and experimental research in animal or cell-based models of AD. The possibility of identifying new disease-modifying drugs for AD targeting NF-kappa B signaling cascade has been discussed in the end.
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  • Vary, J. P., et al. (author)
  • Basis light-front quantization : a new approach to non-perturbative scattering and time-dependent production processes
  • 2013
  • In: Acta Physica Polonica B, Proceedings Supplement. - 1899-2358 .- 2082-7865. ; 6:1, s. 257-262
  • Journal article (peer-reviewed)abstract
    • Hamiltonian light-front quantum field theory constitutes a framework for deriving invariant masses, correlated parton amplitudes of self-bound systems and time-dependent scattering amplitudes. By choosing the lightfront gauge and adopting an orthonormal basis function representation, we obtain a large, sparse, Hamiltonian matrix for mass eigenstates that is solvable by adapting ab initio no-core methods of nuclear many-body theory. In the continuum limit, the infinite matrix limit, we recover full covariance. There is considerable freedom in the choice of the orthonormal and complete set of basis functions with key considerations being convenience and convergence properties. We adopt a two-dimensional harmonic oscillator basis for transverse modes that corresponds with eigensolutions of the soft-wall anti-de Sitter/quantum chromodynamics (AdS/QCD) model obtained from light-front holography. We outline our approach and present preliminary results for non-linear Compton scattering, evaluated non-perturbatively, where a strong (possibly time-dependent) laser field excites an electron that emits a photon.
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11.
  • El-Jawahri, Areej, et al. (author)
  • Impact of pre-transplant depression on outcomes of allogeneic and autologous hematopoietic stem cell transplantation
  • 2017
  • In: Cancer. - : Wiley. - 0008-543X .- 1097-0142. ; 123:10, s. 1828-1838
  • Journal article (peer-reviewed)abstract
    • BACKGROUND: To evaluate the impact of depression before autologous and allogeneic hematopoietic cell transplantation (HCT) on clinical outcomes post-transplantation.METHODS: We analyzed data from the Center for International Blood and Marrow Transplant Research to compare outcomes after autologous (n=3786) or allogeneic (n=7433) HCT for adult patients with hematologic malignancies with an existing diagnosis of pre-HCT depression requiring treatment versus those without pre-HCT depression. Using Cox regression models, we compared overall survival (OS) between patients with or without depression. We compared the number of days alive and out of the hospital in the first 100 days post-HCT using Poisson models. We also compared the incidence of grade 2-4 acute and chronic graft-versus-host disease (GVHD) in allogeneic HCT.RESULTS: The study included 1116 (15%) patients with pre-transplant depression and 6317 (85%) without depression who underwent allogeneic HCT between 2008 and 2012. Pre-transplant depression was associated with lower OS (hazard ratio [HR], 1.13; 95% confidence interval [CI], 1.04-1.23; P=0.004) and a higher incidence of grade 2-4 acute GVHD (HR, 1.25; 95% CI, 1.14-1.37; P<0.0001), but similar incidence of chronic GVHD. Pre-transplant depression was associated with fewer days-alive-and-out-of-the hospital (means ratio [MR]=0.97; 95% CI, 0.95-0.99; P=0.004). There were 512 (13.5%) patients with Pre-transplant depression and 3274 (86.5%) without depression who underwent autologous HCT. Pre-transplant depression in autologous HCT was not associated with OS (HR, 1.15; 95% CI, 0.98-1.34; P=0.096) but was associated with fewer days alive and out of the hospital (MR, 0.98; 95% CI, 0.97-0.99; P=0.002).CONCLUSION: Pre-transplant depression was associated with lower OS and higher risk of acute GVHD among allogeneic HCT recipients and fewer days alive and out of the hospital during the first 100 days after autologous and allogeneic HCT. Patients with pre-transplant depression represent a population that is at risk for post-transplant complications.
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12.
  • Haandrikman, Karen, 1977-, et al. (author)
  • Local Variation in Gendered Family Policy Use : Evidence of Local Gender Contracts?
  • 2021
  • In: Spatial Demography. - : Springer Science and Business Media LLC. - 2364-2289 .- 2164-7070. ; 9, s. 155-186
  • Journal article (peer-reviewed)abstract
    • A central and unique part of Sweden’s family policy programme is care leave that working parents can use when children are sick and cannot attend (pre)school. The gender-equal policy entails that parents may divide the leave as they see fit. However, mothers and fathers do not share care leave equally and care leave patterns may vary geographically. The aim of this paper is to examine the interaction between gendered care leave and geographical context using the theory of gender contracts. We ask how geographical variation in fathers’ share of care leave varies by scale, and how both individual factors and geographical determinants, representing local gender contracts, are associated with fathers’ share of care leave. Distinctive from previous work, we use geocoded full-population register data and individualized neighbourhoods at multiple scales in order to be able to better measure contextual effects on care leave use. We find substantial spatial variation in fathers’ share of care leave, with clustering depending on scale level. Using the nearest 200 fathers with young children, a factor analysis summarizes local gender contracts into three factors labelled as elite, marginalization and private sector. Results show that especially living in local gender contract areas identified as “marginalized” positively affects fathers’ share of care leave. Living in the most segregated neighbourhoods has substantial effects on fathers’ share of care leave, but overall, neighbourhood effects are moderate. A gender contract perspective shows negotiations resulting from locally clustered gendered norms and relative resources between partners influence who stays home with sick children.
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  • Jaarsma, Tiny, et al. (author)
  • Self-care of heart failure patients: practical management recommendations from the Heart Failure Association of the European Society of Cardiology
  • 2021
  • In: European Journal of Heart Failure. - : WILEY. - 1388-9842 .- 1879-0844. ; 23:1, s. 157-174
  • Journal article (peer-reviewed)abstract
    • Self-care is essential in the long-term management of chronic heart failure. Heart failure guidelines stress the importance of patient education on treatment adherence, lifestyle changes, symptom monitoring and adequate response to possible deterioration. Self-care is related to medical and person-centred outcomes in patients with heart failure such as better quality of life as well as lower mortality and readmission rates. Although guidelines give general direction for self-care advice, health care professionals working with patients with heart failure need more specific recommendations. The aim of the management recommendations in this paper is to provide practical advice for health professionals delivering care to patients with heart failure. Recommendations for nutrition, physical activity, medication adherence, psychological status, sleep, leisure and travel, smoking, immunization and preventing infections, symptom monitoring, and symptom management are consistent with information from guidelines, expert consensus documents, recent evidence and expert opinion.
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  • Junquera, Tomas, et al. (author)
  • Design of a New Horizontal Test Cryostat for Scrfcavities at the Uppsala University
  • 2014
  • In: SRF2013: Proceedings of the 16th International Conference on RF Superconductivity. - 9783954501434 ; , s. 325-327
  • Conference paper (other academic/artistic)abstract
    • At Uppsala University, the FREIA facility for researchand development of new accelerators and associatedinstrumentation, is presently in construction. Associatedto a new Helium Liquefier, a Horizontal Test Cryostat willbe used for high power RF tests of completely equippedSC cavities. This paper presents the main characteristicsof the cryostat. Two types of cavities have beenconsidered for test purpose: SC elliptical cavities forfuture free electron lasers and SC cavities for highintensity proton accelerators. A special valve boxincluding a subcooling stage and power coupler coolingwith supercritical Helium supply have been designed, fortemperature operation ranging from 2 K to 4.2 K. Thisfacility will play an essential role in the development andtest of cavities, couplers and cryomodules for the ESSproject. High power RF sources will be installed in orderto allow unique and complete tests of spoke cavities andcryomodules at high nominal peak power.
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  • Norqvist, Mathias, 1971-, et al. (author)
  • Shifts in student attention on algorithmic and creative practice tasks
  • 2023
  • In: Educational Studies in Mathematics. - : Springer. - 0013-1954 .- 1573-0816.
  • Journal article (peer-reviewed)abstract
    • In mathematics classrooms, it is common practice to work through a series of comparable tasks provided in a textbook. A central question in mathematics education is if tasks should be accompanied with solution methods, or if students should construct the solutions themselves. To explore the impact of these two task designs on student behavior during repetitive practice, an eye-tracking study was conducted with 50 upper secondary and university students. Their eye movements were analyzed to study how the two groups shifted their gaze both within and across 10 task sets. The results show that when a solution method was present, the students reread this every time they solved the task, while only giving minute attention to the illustration that carried information supporting mathematical understanding. Students who practiced with tasks without a solution method seemed to construct a solution method by observing the illustration, which later could be retrieved from memory, making this method more efficient in the long run. We discuss the implications for teaching and how tasks without solution methods can increase student focus on important mathematical properties.
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