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Träfflista för sökning "WFRF:(IJzerman H) srt2:(2022)"

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1.	Dorison, CA, et al. (author) In COVID-19 Health Messaging, Loss Framing Increases Anxiety with Little-to-No Concomitant Benefits: Experimental Evidence from 84 Countries 2022 In: Affective science. - : Springer Science and Business Media LLC. - 2662-205X .- 2662-2041. ; 3:3, s. 577-602 Journal article (peer-reviewed)
2.	Wang, K, et al. (author) Author Correction: A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic 2022 In: Nature human behaviour. - : Springer Science and Business Media LLC. - 2397-3374. ; 6:9, s. 1318-1319 Journal article (other academic/artistic)
3.	Bongers, B. J., et al. (author) Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors 2022 In: Scientific Reports. - : Springer Nature. - 2045-2322. ; 12 Journal article (peer-reviewed)abstract G Protein-coupled receptors (GPCRs) are the most frequently exploited drug target family, moreover they are often found mutated in cancer. Here we used a dataset of mutations found in patient samples derived from the Genomic Data Commons and compared it to the natural human variance as exemplified by data from the 1000 genomes project. We explored cancer-related mutation patterns in all GPCR classes combined and individually. While the location of the mutations across the protein domains did not differ significantly in the two datasets, a mutation enrichment in cancer patients was observed among class-specific conserved motifs in GPCRs such as the Class A "DRY" motif. A Two-Entropy Analysis confirmed the correlation between residue conservation and cancer-related mutation frequency. We subsequently created a ranking of high scoring GPCRs, using a multi-objective approach (Pareto Front Ranking). Our approach was confirmed by re-discovery of established cancer targets such as the LPA and mGlu receptor families, but also discovered novel GPCRs which had not been linked to cancer before such as the P2Y Receptor 10 (P2RY10). Overall, this study presents a list of GPCRs that are amenable to experimental follow up to elucidate their role in cancer.
4.	Cuppen, E, et al. (author) Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care 2022 In: JCO precision oncology. - 2473-4284. ; 6, s. e2200245- Journal article (peer-reviewed)
5.	Cuppen, E, et al. (author) Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care 2022 In: JCO precision oncology. - 2473-4284. ; 6, s. e2200245- Journal article (peer-reviewed)
6.	Degeling, K, et al. (author) Comparing Modeling Approaches for Discrete Event Simulations With Competing Risks Based on Censored Individual Patient Data: A Simulation Study and Illustration in Colorectal Cancer 2022 In: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. - : Elsevier BV. - 1524-4733. ; 25:1, s. 104-115 Journal article (peer-reviewed)

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Result 1-6 of 6

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Type of publication: journal article (6)

Type of content: peer-reviewed (5); other academic/artistic (1)

Author/Editor: Wang, K. (2); Urban, J. (2); Becker, M (2); Ivanov, A. (2); McCarthy, R. (2); Suter, L. (2); show more...; Vilar, R. (2); Habib, S. (2); Wolfe, K (2); Evans, K. (2); Stoyanova, A (2); Song, X. (2); Chen, Z. (2); Campo, E (2); Rosenquist, R. (2); Schmidt, K. (2); Ishii, T. (2); Yamada, Y. (2); Moreau, D (2); Wielgus, M. (2); Ahmed, A (2); Feldman, G. (2); Maldonado, MA (2); FERREIRA, A (2); Ahlgren, L (2); Lee, JM (2); Gill, T (2); Westerlund, M. (2); Banik, G. (2); Cuppen, E (2); Nakagawa, H (2); Yu, K (2); Schuh, A (2); Andre, F (2); Oliveira, R. (2); Azevedo, F (2); Voracek, M (2); Hartanto, A. (2); Manley, H. (2); Micheli, L. (2); Arriaga, P. (2); Bernardo, M. (2); Baskin, E (2); Vally, Z. (2); Sirota, M (2); Adamkovic, M (2); Adamus, S (2); Albayrak-Aydemir, N (2); Alves, SG (2); Anjum, G (2); show less...

University: Karolinska Institutet (5); Uppsala University (1); Stockholm University (1)

Language: English (6)

Research subject (UKÄ/SCB): Medical and Health Sciences (1); Social Sciences (1)

Year: 2022 (6)Undo refine

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